Class 1. Persistent Pulmonary Hypertension of the Newborn

Intravenous sildenafil for treatment of early pulmonary hypertension in preterm infants

Lukas Schroeder, Paulina Monno, Brigitte Strizek, Till Dresbach, Andreas Mueller, Florian KipfmuellerUniversity Children’s Hospital Bonn and University Hospital Bonn.Germany Scientific ReportsSci Rep 2023; 13DOI: 10.1038/s41598-023-35387-y AbstractData is lacking on the effect of continuous intravenous sildenafil treatment in preterm infants with early pulmonary hypertension (PH), especially in very low birth weight (VLBW) infants. Preterm infants (< 37 […]

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Neonatal Outcomes of Term Infants Born with Meconium-Stained Amniotic Fluid

Carlo Dani, Martina Ciarcià1, Vittoria Barone, Mariarosaria Di Tommaso, Federico Mecacci, Lucia Pasquini, Simone PratesiCareggi University Hospital, Largo Brambilla. University of Florence. Italy ChildrenChildren 2023; 10 DOI: 10.3390/children10050780 AbstractBackground Meconium-stained amniotic fluid (MSAF) is considered an alarming sign of possible fetal compromise and it has recently been reported that neonatal outcome correlates with the degree of meconium

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Novel scoring tool of hypoxemic respiratory failure and pulmonary hypertension for defining severity of persistent pulmonary hypertension of newborn

Sage Timberline, Avni Bhatt, Sherzana Sunderji, Daniel J. Tancredi, Satyan Lakshminrusimha, Heather SiefkesUniversity of Virginia. University of California, Davis. United States Journal of PerinatologyJ Perinatol 2023; DOI: 10.1038/s41372-023-01762-w AbstractObjective: To obtain preliminary validity data for a hypoxemic respiratory failure/pulmonary hypertension (HRF/PH) score for classifying persistent pulmonary hypertension of the newborn (PPHN).Study design: Retrospective chart review of 100 consecutive

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Evaluation of Postnatal Complications in Clinical and Histological Chorioamnionitis in Extremely Preterm Infants: A Japanese Cohort Study

Shuji Ishida, Hidehiko Nakanishi, Rika Sekiya, Kohei Kawada, Yukako Kosaka, Ayano Yamaguchi, Mari Ooka, On befalf of the Neonatal Research Network of JapanKitasato University.Japan American Journal of PerinatologyAm J Perinatol 2023; DOI: 10.1055/a-2113-4332 AbstractObjective: Terminating pregnancy appropriately before the intrauterine infection has progressed may have an improved prognosis for preterm infants. We evaluate how the combination of histological chorioamnionitis (hCAM) and clinical chorioamnionitis

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Diastolic ventricular function in persistent pulmonary hypertension of the newborn

Kévin Le Duc, Thameur Rakza, Jean Benoit Baudelet, Mohamed Riadh Boukhris, Sébastien Mur, Ali Houeijeh, Laurent StormePôle Femme-Mère-Nouveau-Né, Hôpital Jeanne de Flandre, Centre Hospitalier Universitaire de Lille and University of Lille. France Frontiers in PediatricsFront Pediatr 2023;DOI: 10.3389/fped.2023.1175178 AbstractBackground: Persistent pulmonary hypertension of the newborn (PPHN) is usually considered a consequence of impaired pulmonary circulation. However, little

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Practices and Outcomes from a Prospective, Multicenter Registry for Preterm Newborns with Pulmonary Hypertension

Nicolle Fernandez Dyess, Claire Palmer, Roger F. Soll, Reese H. Clark, Steven H. Abman, John P. Kinsella and the Preterm Newborn Pulmonary Hypertension Registry Study Group with Multiple Collaborating InvestigatorsUniversity of Colorado School of Medicine. University of Vermont. Pediatrix Center for Research. Multiple Collaborating Institutions.United States Journal of PediatricsJ Pediatr 2023; DOI: 10.1016/j.jpeds.2023.113614 AbstractObjective: To describe current

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Risk factors of transient tachypnea of the newborn developing into pulmonary hypertension of the newborn: a case-control study

Gunlawadee Maneenil, Waricha Janjindamai, Supaporn Dissaneevate, Anucha ThatrimontrichaiPrince of Songkla UniversityThailand Asian BiomedicineAsian Biomed 2023; 16: 310-315DOI: 10.2478/abm-2022-0034 AbstractBackground: Transient tachypnea of the newborn (TTN) is the consequence of delayed resorption of lung fluid. When TTN develops, the infant may develop severe hypoxemia and progress to persistent pulmonary hypertension of the newborn (PPHN).Objectives: To examine factors associated with

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Association between immediate oxygenation response and survival in preterm infants receiving rescue inhaled nitric oxide therapy for hypoxemia from pulmonary hypertension: A systematic review and meta-analysis

Michelle Baczynski, Bonny Jasani, Charmaine De Castro, Carlo Dani, Nimish V. Subhedar, Praveen Chandrasekharan, Satvan Lakshminrusimha, Patrick J. McNamara, Adrianne R. Bishchoff, Amish JainMount Sinai Hospital. Hospital for Sick Children. Careggi University Hospital of Florence and University of Florence. Liverpool Women’s Hospital. University at Buffalo. UC Davis Children’s Hospital. University of Iowa. Canada, Italy, United

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Meconium aspiration syndrome: a comprehensive review

Ahmed Osman, Cecilie Halling, Mary Crume, Hayat Al Tabosh, Namrita Odackal, Molly K. BallThe Ohio State University and Nationwide Children’s Hospital. United States Journal of PerinatologyJ Perinatol 2023; DOI: 10.1038/s41372-023-01708-2 AbstractMeconium aspiration syndrome (MAS) is a complex respiratory disease that continues to be associated with significant morbidities and mortality. The pathophysiological mechanisms of MAS include airway

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Pulmonary hypertension associated with acute or chronic lung diseases in the preterm and term neonate and infant. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK

Anne Hilgendorff, Christian Apitz, Damien Bonnet, Georg HansmannDr von Haunersche Children’s Hospital. Children’s Hospital, University of Ulm. Hôpital Necker Enfants Malades, APHP, Université Paris Descartes. Hannover Medical School. Germany and France HeartHeart 2016; 102 Suppl 2: ii49-56DOI: 10.1136/heartjnl-2015-308591 AbstractPersistent pulmonary hypertension of the newborn (PPHN) is the most common neonatal form and mostly reversible after a few days

Pulmonary hypertension associated with acute or chronic lung diseases in the preterm and term neonate and infant. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK Read More »

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