Class 1. Persistent Pulmonary Hypertension of the Newborn

Prostaglandin-E1 infusion in persistent pulmonary hypertension of the newborn

Stephanie M. Tsoi, Hythem Nawaytou, Hassan Almeneisi, Martina Steurer, Yili Zhao, Jeffrey R. Fineman, Roberta L. KellerUniversity of California San Francisco.United States Pediatric PulmonologyPediatr Pulmonol 2023; DOI: 10.1002/ppul.26759 AbstractBackground: Neonates with persistent pulmonary hypertension of the newborn (PPHN) can present with hypoxia and right ventricular dysfunction with resultant inadequate oxygen delivery and end-organ damage. This study describes […]

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Impact of persistent pulmonary hypertension and oxygenation on brain injury in neonates with neonatal encephalopathy treated with therapeutic hypothermia

Keira C. Kilmartin, Asim Al Balushi, Gabriel Altit, Anie Lapointe, Emmanouil Rampakakis, Stephanie Barbosa Vargas, Julie Maluorni, Pia WintermarkMontreal Children’s Hospital and McGill University. National Heart Centre. University of Montreal. Canada and Oman Journal of PerinatologyJ Perinatol 2023; DOI: 10.1038/s41372-023-01805-2 AbstractObjective: To investigate the effects of persistent pulmonary hypertension (PPHN) and oxygenation on outcome of neonates with

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Successful Weaning From Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO) After Initiation of Inhaled Epoprostenol in a Neonate With Refractory Persistent Pulmonary Hypertension of the Newborn (PPHN)

Irfan Shehzad, Ashish Banker, Bibhuti Das, Adil Humayun, Hale Wills, Muppala Raju, Niraj VoraBaylor Scott & White Health.United States CureusCureus 2023; DOI: 10.7759/cureus.45595 AbstractDespite improvements in the medical management of persistent pulmonary hypertension of the newborn (PPHN), a significant number of patients persist with inadequate gas exchange and are treated with extracorporeal membrane oxygenation (ECMO). Prolonged

Successful Weaning From Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO) After Initiation of Inhaled Epoprostenol in a Neonate With Refractory Persistent Pulmonary Hypertension of the Newborn (PPHN) Read More »

A Neonate With Cytokine Storm Managed With Steroids, Therapeutic Plasma Exchange, and Tocilizumab

Amy LiKamWa, Kaitlin Kobaitri, Balagangadhar R. TotapallyHerbert Wertheim College of Medicine. Nicklaus Children’s Hospital.United States CureusCureus 2023; 15DOI: 10.7759/cureus.45138 AbstractNeonatal cytokine storms, though rare, can induce hyperinflammation due to elevated interleukin-6 (IL-6), triggering multiorgan failure. We present the case of a term male neonate necessitating extracorporeal membrane oxygenation (ECMO) post-birth for persistent pulmonary hypertension due to

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Incidence and types of congenital heart disease at a referral hospital in Jordan: retrospective study from a tertiary center

Abeer A. Hasan, Naser Aldain A. Abu Lehyah, Moath K. Al Tarawneh, Mahmoud Y. Abbad, Areen G. Fraijat, Razan A. Al-Jammal, Dania M. Moamar, Qasem A. Shersheer, Scott O. Guthrie, Joseph R. StarnesMaternity and Children’s Hospital at Al Bashir Hospital. Vanderbilt University Medical Center, Nashville.Jordan and United States Frontiers in PediatricsFront Pediatr 2023; 11DOI: 10.3389/fped.2023.1261130 AbstractBackground: Congenital

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Risk factors and neonatal outcomes of pulmonary air leak syndrome in extremely preterm infants: A nationwide descriptive cohort study

Seong Hee Oh, Hyun-Seung Jin, Chan-Hoo ParkUniversity of Ulsan College of Medicine and Gangneung Asan Hospital. Gyeongsang National University College of Medicine and Gyeongsang National University Changwon Hospital.Republic of Korea MedicineMedicine 2023; 102DOI: 10.1097/MD.0000000000034759 AbstractMost extremely preterm infants (EPIs), who were born before 28 weeks of gestation, with pulmonary air leak syndrome (ALS) are symptomatic, often

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Inhaled nitric oxide use in newborns

Souvik Mitra, Gabriel AltitCanadian Paediatric Society.Canada Paediatrics and Child HealthPaediatr Child Health 2023; 28: 119-127DOI: 10.1093/pch/pxac107 AbstractInhaled nitric oxide (iNO), a selective pulmonary vasodilator, is used as a therapeutic modality in infants with hypoxemic respiratory failure (HRF) associated with persistent pulmonary hypertension of the newborn (PPHN). iNO should ideally be initiated following echocardiographic confirmation of PPHN.

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Short-time mortality and severe complications of very premature infants-a multicenter retrospective cohort study from Jiangsu Province during 2019-2021

Ya Pan, Huaiyan Wang, Yan Xu, Xiaohua Zhang, Xiaoqing Chen, Xueting Liu, Songlin Liu, Yan Gao, Weiwei Hou, Zhaojun Pan, Xinping Wu, Mei Xue, Mingfu Wu, Huimin Ju, Weimin Wu, Shuping HanWomen’s Hospital of Nanjing Medical University and Nanjing Maternity and Child Health Care Hospital. Changzhou Maternity and Child Health Care Hospital. Affiliated Hospital of

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Intravenous sildenafil for treatment of early pulmonary hypertension in preterm infants

Lukas Schroeder, Paulina Monno, Brigitte Strizek, Till Dresbach, Andreas Mueller, Florian KipfmuellerUniversity Children’s Hospital Bonn and University Hospital Bonn.Germany Scientific ReportsSci Rep 2023; 13DOI: 10.1038/s41598-023-35387-y AbstractData is lacking on the effect of continuous intravenous sildenafil treatment in preterm infants with early pulmonary hypertension (PH), especially in very low birth weight (VLBW) infants. Preterm infants (< 37

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Neonatal Outcomes of Term Infants Born with Meconium-Stained Amniotic Fluid

Carlo Dani, Martina Ciarcià1, Vittoria Barone, Mariarosaria Di Tommaso, Federico Mecacci, Lucia Pasquini, Simone PratesiCareggi University Hospital, Largo Brambilla. University of Florence. Italy ChildrenChildren 2023; 10 DOI: 10.3390/children10050780 AbstractBackground Meconium-stained amniotic fluid (MSAF) is considered an alarming sign of possible fetal compromise and it has recently been reported that neonatal outcome correlates with the degree of meconium

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