Class 1. Persistent Pulmonary Hypertension of the Newborn

Circulating Intercellular Adhesion Molecule as a Novel Marker of Pulmonary Hypertension in Newborn

Antoine Fakhry AbdelMassih, Sherif ElAnwary, Nourhan Taha, Noha Radwan, Mahmoud Othman AbouDeifCairo University Children Hospital and Cairo University. Sheikh Khalifa Medical City. Egypt and United Arab Emirates Indian PediatricsIndian Pediatr 2025;DOI: 10.1007/s13312-025-00037-1 AbstractBackground: IntercellularAQ1 adhesion molecules (ICAMs) are released from the endothelium in response to shear stress. Their role in persistent pulmonary hypertension (PPHN) remains un-investigated.Methodology: Sixty neonates […]

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Characteristics and outcomes of preterm infants with early pulmonary hypertension

Rachel Mullaly, Aisling Smith, Claire Murphy, Seán Armstrong, Orla Franklin, Naomi McCallion, Afif EL-KhuffashRotunda Hospital. Royal College of Surgeons in Ireland. Children’s Health Ireland at Crumlin.Ireland Journal of PerinatologyJ Perinatol 2025; DOI: 10.1038/s41372-025-02295-0 AbstractObjective: This study investigates incidence, outcomes and echocardiographic characteristics of preterm infants with early pulmonary hypertension (PH) compared to those without.Study design: A prospective observational

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miR-29 inhibits endothelial-to-mesenchymal transition in pulmonary hypertension of the newborn by regulating LRP6

Yingjie Wang, Le Sun, Xianxian Jia, Miao Yang, Wei XuShengjing Hospital of China Medical University.China FASEB JournalFASEB J 2025; 39:DOI: 10.1096/fj.202401069RRR AbstractPulmonary hypertension of the newborn (PHN) is a common pulmonary vascular disease in newborns, affecting the prognosis of affected infants and even leading to death. Currently, there is still no specific targeted prevention and treatment

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Prolonged postnatal adaptation and enhanced prevalence of congenital heart diseases due to altitude may contribute to newborn mortality in Bolivia

Alexandra Heath, Inge von Alvensleben, Jesús Ardiles Spielvogel, Pablo Freudenthal, Johannes Trapp, Ivanna Noya, Miguel Gálvez, Fanny Mendizábal, Mariana Gonzales, Ceylan Apaza, Leibniz Sanga, Erin Mc Cann, Colleen G. JulianKardiozentrum. University of Witten. University of Munich. Hospital ‘Arco Iris’. Hospital Municipal Boliviano Holandés. University of Cincinnati. University of Colorado.Bolivia, Germany and United States Experimental PhysiologyExp

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Meconium aspiration syndrome and associated factors among neonates admitted at neonatal intensive care unit at Northwest Ethiopia comprehensive specialized hospitals Northwest Ethiopia 2023

Marta Adugna, Kibret Asmare, Amare WondimUniversity of Gondar. Ethiopia BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-024-05181-4 AbstractIntroduction: Meconium aspiration syndrome is a life-threatening respiratory disease due to the aspiration of meconium-stained amniotic fluid into the lungs, resulting in neonatal morbidity and mortality. Impacts of meconium aspiration syndrome include respiratory failure, intellectual disability, persistent pulmonary hypertension, and

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Prevalence and outcomes of air leak syndrome and subtypes in neonates in the United States

Adam Beaton, Prithvi Sendi, Paul A. Martinez, Balagangadhar R. TotapallyCohen Children’s Medical Center. Nicklaus Children’s Hospital. Florida International University. United States Journal of Neonatal-Perinatal MedicineJ Neonatal Perinatal Med 2025; 17: 846-857DOI: 10.1177/19345798241308491 AbstractObjectives: To describe the prevalence, risk factors, and outcomes for neonatal air leak syndrome and its subtypes (pneumothorax, pneumomediastinum, pneumopericardium, pulmonary interstitial emphysema, and pneumoperitoneum), evaluate variables associated with the development

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Prospective Evaluation of Pulse Oximetry Screening for Critical Congenital Heart Disease in a Jordanian Tertiary Hospital: High Incidence and Early Detection Challenges

Naser Aldain A. Abu Lehyah, Abeer A. Hasan, Mahmoud Y. Abbad, Razan A. Al-Jammal, Moath K. Al Tarawneh, Dima Abu Nasrieh, Haneen A. Banihani, Saif N. Aburumman, Areen G. Fraijat, Heba M. Alhawamdeh, Qasem A. Shersheer, Milad Kh. Al-Awawdeh, Scott O. Guthrie, Joseph R. StarnesWomen’s and Children’s Hospital of Al Bashir Hospitals. King Abdullah University

Prospective Evaluation of Pulse Oximetry Screening for Critical Congenital Heart Disease in a Jordanian Tertiary Hospital: High Incidence and Early Detection Challenges Read More »

Developing a Neonatal Pulmonary Hypertension Core Outcome Set (NeoPH COS)-A Study Protocol

Cara Ellen Morgan, Kerry Woolfall, Natasharazia Aikman, Crhistopher Gale, Nimish Subhedar, the RePHyNeConsortiumLiverpool Women’s NHS Trust and Univeristy of Liverppool. Imperial College London.United Kingdom Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70052 AbstractPulmonary hypertension (PH) in newborn babies is a relatively rare, heterogeneous condition that has high associated mortality in the neonatal period and beyond. There are

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Screening For Critical Congenital Heart Disease Using Pulse-Oximetry, The First Egyptian Multicentre Study

Mohammad Eltahlawi, Alaa Elghamrawy, Maiy Hamdy Elsayed, Mona Hafez, Asmaa Elmesiry, Mohamed Bayomy, Hani Adel, Mahmoud Elfayoumy, Sahbaa Hafez, Said Morsy, Mahmoud Elhady, Baher Nashy, Mohamed Abo ElelaZagazig University. Ministry of Health. Ain Shams University. Mansoura University. Tanta University. Alazhar University. Alexandria University. Benha University. Assuit University.Egypt Cardiology in the YoungCardiol Young 2025; DOI: 10.1017/S1047951125000289 AbstractBackground: Congenital

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Response to Inhaled Nitric Oxide and Mortality Among Very Preterm Neonates With Pulmonary Hypertension

Michelle Baczynski, Dany Weisz, Laura Thomas, Stephanie Fevrier, Michael Castaldo, Amuchou Soraisham, Abbas Hyderi, Rula Agarushi, Soume Bhattacharya, Renjini Lalitha, Amneet Sidhu, Muzafar Gani Abdul Wahab, Gabriel Altit, Audrey Hébert, Deepak Louis, Yasser Elsayed, Souvik Mitra, Poorva Deshpande, Ashraf Kharrat, Faith Zhu, Joseph Ting, Eugene Yoon, Prakesh S. Shah, Amish Jain for the Canadian Neonatal

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