Class 1. Drug-induced and Toxin-induced Pulmonary Hypertension

Pharmacological Gq inhibition induces strong pulmonary vasorelaxation and reverses pulmonary hypertension

Alexander Seidinger, Richard Roberts, Yan Bai, Marion Müller, Eva Pfeil, Michaela Matthey, Sarah Rieck, Judith Alenfelder, Gabriele M. KUonig, Alexander Pfeifer, Evi Kostenis, Anna Klinke, Bernd K. Fleischmann, Daniela WenzelUniversity Hospital of the Ruhr University of Bochum and Ruhr University of Bochum. University Hospital of Nottingham. Massachusetts General Hospital and Harvard Medical School. University of […]

Pharmacological Gq inhibition induces strong pulmonary vasorelaxation and reverses pulmonary hypertension Read More »

Post-treatment with Resolvin D1 attenuates pulmonary hypertension by inhibiting endothelial-to-mesenchymal transition

Xinyu Lia, Hui Li, Bo Feng, Xiaoyan Chen, Ting Chen, Jiafei Lu, Huating Xie, Nana Su, Houlin Chen, Chenghao Lou, Runxin Zhuang, Xi Chen, Shengwei Jin, Yu HaoSecond Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University. Ruijin Hospital and Shanghai Jiao Tong University School of Medicine. China Biomedicine and PharmacotherapyBiomed Pharmacother 2024; DOI: 10.1016/j.biopha.2024.117023

Post-treatment with Resolvin D1 attenuates pulmonary hypertension by inhibiting endothelial-to-mesenchymal transition Read More »

Pneumonectomy combined with SU5416 or monocrotaline pyrrole does not cause severe pulmonary hypertension in mice

Xiao-Qing Sun, Timothy Klouda, Suzanne Barnasconi, Ingrid Schalij, Janne Schwab, Anders Hammer Nielsen-Kudsk, Julie Sørensen Axelsen, Asger Andersen, Jurjan Aman, Frances S. de Man, Harm Jan Bogaard, Ke Yuan, Keimei YoshidaAmsterdam UMC. Boston Children’s Hospital. Aarhus University Hospital.Netherlands, United States and Denmark American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell

Pneumonectomy combined with SU5416 or monocrotaline pyrrole does not cause severe pulmonary hypertension in mice Read More »

Dasatinib-induced pleural effusions, pericardial effusion and pulmonary arterial hypertension: a case report

Wei Zhao, Kai Wang, Liting Yu, Ying Guo, Zhiling LiShanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine.China Translational PediatricsTransl Pediatr 2024; 13: 673-681DOI: 10.21037/tp-23-517 AbstractBackground: Pleural effusion, pericardial effusion, and pulmonary arterial hypertension have been shown to have potential associations with the use of dasatinib in adults. However, due to the limited data

Dasatinib-induced pleural effusions, pericardial effusion and pulmonary arterial hypertension: a case report Read More »

GLI1+ Cells Contribute to Vascular Remodeling in Pulmonary Hypertension

Xuran Chu, Vahid Kheirollahi, Arun Lingampally, Prakash Chelladurai, Chanil Valasarajan, Ana Ivonne Vasquez-Armendariz, Stefan Hadzic, Ali Khadim, Oleg Pak, Stefano Rivetti, Jochen Wilhelm, Marek Bartkuhn, Slaven Crnkovic, Alena Moiseenko, Mohika Heiner, Simone Kraut, Leila Sotoodeh, Janine Koepke, Guilherme Valente, Clemens Ruppert, Thomas Braun, Christos SamakovlisIoannis Alexopoulos, MAria Looso, Cho-Mong Chao, Susanne Herold, Werner Seeger, Grazyna

GLI1+ Cells Contribute to Vascular Remodeling in Pulmonary Hypertension Read More »

Tumor Necrosis Factor-α-Induced Protein-8-like 2 Transfected Adipose-Derived Stem Cells Regulated the Dysfunction of Monocrotaline Pyrrole-Induced Pulmonary Arterial Smooth Muscle Cells and Pulmonary Arterial Endothelial Cells

Jing Li, Xin He, Feng Liu, Kinglong Zheng, Jing JiangFirst Affiliated Hospital of Xi’an Jiaotong University. Fourth Military Medical University.China Journal of Cardiovascular PharmacologyJ Cardiovasc Pharmacol 2024; 83:73-85DOI: 10.1097/FJC.0000000000001505 AbstractPulmonary arterial hypertension (PAH) is characterized by pulmonary arterial endothelial cell (PAEC) dysfunction and pulmonary arterial smooth muscle cell (PASMC) activation. For decades, the therapies for PAH

Tumor Necrosis Factor-α-Induced Protein-8-like 2 Transfected Adipose-Derived Stem Cells Regulated the Dysfunction of Monocrotaline Pyrrole-Induced Pulmonary Arterial Smooth Muscle Cells and Pulmonary Arterial Endothelial Cells Read More »

Maternal treatment with selective serotonin reuptake inhibitors during pregnancy and delayed neonatal adaptation: a population-based cohort study

Marie-Coralie Cornet, Yvonne W. Wu, Heather Forquer, Lyndsay A. Avalos, Achyuth Sriram, Aaron W. Scheffler, Thomas B. Newman, Michael W. KuzniewiczUniversity of California San Francisco. Kaiser Permanente Northern California.United States Archives of Disease in Children Fetal and Neonatal EditionArch Dis Child Fetal Neonatal Ed 2023; DOI: 10.1136/archdischild-2023-326049 AbstractObjective: Selective serotonin reuptake inhibitor (SSRI) use is common in

Maternal treatment with selective serotonin reuptake inhibitors during pregnancy and delayed neonatal adaptation: a population-based cohort study Read More »

Low-dose diazoxide is safe and effective in infants with transient hyperinsulinism

Neha Malhotra, Daphne Yau, Annaruby Cunjamalay, Buddhi Gunasekara, Athanasakopoulou S., Clare Gilbert, Kate Morgan, Mehul Dattani, Antonia DastamaniGreat Ormond Street Hospital for Children. University of Saskatchewan. Medical School of Queen Mary University.United Kingdom and Canada Clinical EndocrinologyClin Endocrinol 2023; DOI: 10.1111/cen.14987 AbstractObjective: Transient hyperinsulinism (THI) is the most common form of recurrent hypoglycaemia in neonates beyond the

Low-dose diazoxide is safe and effective in infants with transient hyperinsulinism Read More »

Fenfluramine in the treatment of Dravet syndrome: Results of a third randomized, placebo-controlled clinical trial

Joseph Sullivan, Lieven Lagae, J. Helen Cross, Orrin Devinsky, Renzo Guerrini, Kelly G. Knupp, Linda Laux, Marina Nikanorova, Tilman Polster, Dinesh Talwar, Berten Ceulemans, Rima Nabbout, Gail M. Farfel, Bradley S. Galer, Arnaold R. Gammaitoni, Michael Lock, Anupam Agarwal, Ingrid E. Scheffer, The FAiRE DS Study GroupUniversity of California San Francisco. University of Leuven. Great

Fenfluramine in the treatment of Dravet syndrome: Results of a third randomized, placebo-controlled clinical trial Read More »

Dasatinib-induced pulmonary arterial hypertension in pediatric acute lymphoblastic leukemia with Philadelphia chromosome: A report of two cases

Sujie Tang, Hao Xiong, Zhi Chen, Li Yang, Ming Sun, Wenjie Lu, Zhuo Wang, Fang Tao, Min Wu, Linlin Luo, Zuofeng LiJianghan University. Wuhan Children’s Hospital. Medical College of Wuhan University of Science and Technology.China Pediatric Blood and CancerPediatr Blood Cancer 2023; DOI: 10.1002/pbc.30349 AbstractNo Abstract CategoryClass I. Drug-induced and Toxin-induced Pulmonary Hypertension Age Focus: Pediatric

Dasatinib-induced pulmonary arterial hypertension in pediatric acute lymphoblastic leukemia with Philadelphia chromosome: A report of two cases Read More »

Scroll to Top