Class 1. Drug-induced and Toxin-induced Pulmonary Hypertension Archives

A Case of Pulmonary Hypertensive Crisis Following Treatment of Retinopathy of Prematurity in an Extremely Preterm Infant

Naofumi Hanyu, Shonosuke Nara, Toshihiro Nakayama, Gaku YamanakaTokyo Medical University.Japan Pediatrics InternationalPediatr Int 2026; 68: DOI: 10.1111/ped.70558 AbstractAbstract Not Available CategoryClass III. Pulmonary Hypertension Associated with Lung DiseaseClass I. Drug-induced and Toxin-induced Pulmonary Hypertension Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication Article Access Free

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Clinical and Hormonal Characteristics and Short-Term Outcomes of Diazoxide Use in Hypoglycemic Neonates: A Retrospective Cohort Study

Sevil Bali, Burcu CebeciHaseki Training and Research Hospital and University of Health Sciences.Turkey ChildrenChildren 2026; 13: DOI: 10.3390/children13091157 AbstractBackground/Objectives: Diazoxide is used for persistent or recurrent hypoglycemia when the clinical and biochemical pattern is compatible with hyperinsulinism, but neonatal treatment populations are heterogeneous. We evaluated the clinical and hormonal characteristics and short-term outcomes associated with

Clinical and Hormonal Characteristics and Short-Term Outcomes of Diazoxide Use in Hypoglycemic Neonates: A Retrospective Cohort Study Read More »

Heterogeneous nuclear ribonucleoprotein A1 as a candidate associated with pulmonary vascular remodeling in pulmonary arterial hypertension

Yoshihito Morimoto, Yoshiaki Sato, Katsuhiro Kato, Hidenori Yamamoto, Kentaro Suzuki, Kiyotaka Go, Yoshie Fukasawa, Naoki Ohashi, Yoshiyuki Takahashi, Taichi KatoNagoya University Graduate School of Medicine and Nagoya University Hospital. National Cerebral and Cardiovascular Center. Japan Journal of Molecular and Cellular Cardiology PlusJ Mol Cell Cardiol Plus 2026; 18: DOI: 10.1016/j.jmccpl.2026.100867 AbstractRationale: Although plexiform lesion (PL)

Heterogeneous nuclear ribonucleoprotein A1 as a candidate associated with pulmonary vascular remodeling in pulmonary arterial hypertension Read More »

The NLRP3 Inflammasome Increases Pulmonary Vascular Remodeling in Experimental Pulmonary Arterial Hypertension

Emmanouil Mavrogiannis, Rebeca Weldeghebreal, Iris R. Schilthuis, Zain K. Fal, Niels J. Kloosterhuis, Mirjam H. Koster, Wim Timens, Johannes M. Douwes, Rolf M. F. Berger, Marit WesterterpBeatrix Children’s Hospital, University Medical Center Groningen and University of Groningen. Netherlands Pulmonary CirculationPulm Circ 2026; 16: DOI: 10.1002/pul2.70354 AbstractPulmonary arterial hypertension (PAH) is a progressive vasculopathy leading to right-sided

The NLRP3 Inflammasome Increases Pulmonary Vascular Remodeling in Experimental Pulmonary Arterial Hypertension Read More »

Neonatal Outcomes Following Selective Serotonin Reuptake Inhibitor Use During Pregnancy

Layla Aref, Jacob J. Hughey, Sherwin Shirazi, Jennifer M. S. Sucre, Lisa BastaracheVanderbilt University Medical Center, Vanderbilt University School of Medicine and Vanderbilt University.United States Journal of the American Medical Association Network OpenJAMA Netw Open 2026; 9: DOI: 10.1001/jamanetworkopen.2026.22790 AbstractImportance: Evaluating the safety of selective serotonin reuptake inhibitors (SSRIs) during pregnancy is challenging due to ethical barriers

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Inhalable extracellular vesicle delivered IL-10 mRNA attenuates pulmonary hypertension in rats

Guoliang Wang, Jie Liu, Peiyi Bai, Hong Jiao, Xiaohui Kong, Zhangke Guo, Gaopeng Li, Aijun LiuBeijing Children’s Hospital, Beijing Pediatric Research Institute, Capital Medical University and National Center for Children’s Health. Shanxi Bethune Hospital, Third Hospital of Shanxi Medical University, Shanxi Academy of Medical Sciences and Tongji Shanxi Hospital. General Hospital of Taiyuan Iron and

Inhalable extracellular vesicle delivered IL-10 mRNA attenuates pulmonary hypertension in rats Read More »

Non-invasive surrogate of main pulmonary artery stiffness is associated with right ventricular function in experimental pulmonary arterial hypertension

John D. Dauz, Bahram Mirani, J. Paul Santerre, Michelle P. Bendeck, Craig A. Simmons, Mark K. FriedbergHospital for Sick Children and University of Toronto. Ted Rogers Centre for Heart Research. Canada American Journal of Physiology Heart and Circulatory PhysiologyAm J Physiol Heart Circ Physiol 2026; DOI: 10.1152/ajpheart.00459.2026 AbstractMain pulmonary artery (MPA) stiffening increases right ventricular (RV)

Non-invasive surrogate of main pulmonary artery stiffness is associated with right ventricular function in experimental pulmonary arterial hypertension Read More »

Reversible Pulmonary Arterial Hypertension Due to Fenfluramine in a Young Child: A Case Report

Uzoma Ndukwe, Adrianne Parkey, Debopam Samanta, Abdelrahman Masri, Erin WillisUniversity of Arkansas for Medical Sciences.United States CureusCureus 2026; 18: DOI: 10.7759/cureus.108354 AbstractFenfluramine is approved for Dravet syndrome and Lennox-Gastaut syndrome (LGS) in children under two years of age and is increasingly used off-label for developmental and epileptic encephalopathies (DEEs). Due to the risk of pulmonary arterial

Reversible Pulmonary Arterial Hypertension Due to Fenfluramine in a Young Child: A Case Report Read More »

[Pulmonary Arterial Hypertension Impairs Duodenal Barrier Integrity in Rats]

Shouei Ishimaru, Satoshi Mizuno, Tomoya Tanada, Daisuke Saito, Keiichi Hirono, Keijiro Ibuki, Masato TaguchiUniversity of Toyama.Japan Yakugaku Zasshi (Journal of the Pharmaceutical Society of Japan)Yakugaku Zasshi 2026; DOI: 10.1248/yakushi.25-00165 AbstractPulmonary arterial hypertension (PAH) is a progressive pulmonary vascular disease that leads to right heart failure and systemic venous congestion. Such congestion can impair multiple organs, including

[Pulmonary Arterial Hypertension Impairs Duodenal Barrier Integrity in Rats] Read More »

Cx43 mediates nicotine-induced enhancement of mouse pulmonary arterial tone by downregulating Kv1.2 and Kv2.1 channels

Xiaomin Hou, Xuelu Jiang, Xin Meng, Jin Zhou, Di Xi, Xiaoxia Ren, Ming Gao, Yong’e Liu, Xiao Luo Yiwei Shi, Xiaojiang QinShanxi Medical University. China-Japan Friendship Hospital. Shanxi Coal Central Hospital. First hospital of Shanxi Medical University. China Food and Chemical ToxicologyFood Chem Toxicol 2026; DOI: 10.1016/j.fct.2026.116182 AbstractPulmonary hypertension (PH) is a chronic and complex condition

Cx43 mediates nicotine-induced enhancement of mouse pulmonary arterial tone by downregulating Kv1.2 and Kv2.1 channels Read More »