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Airway Anomalies Predict Risk of Pediatric Pulmonary Hypertension

Elana R. Kriegel, Aditya Srinivasen, Luke Mammen, Harini Venkataganesh, Jess T. Randall, Lara ReichertAlbany Medical College and Albany Medical Center.United States Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.71028 AbstractIntroduction: Pediatric pulmonary hypertension (PH) significantly contributes to morbidity and mortality due to the progressive nature of the disease in some subtypes, which leads to severe right heart failure, […]

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Clinical characteristics and impact of exchange transfusion in infant pertussis with extreme leukocytosis

Yuanyuan Wu, Chuan GanSecond Affiliated Hospital of Chongqing Medical University, Children’s Hospital of Chongqing Medical University and Chongqing Medical University. Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity.China Italian Journal of PediatricsItal J Pediatr 2025; 51: DOI: 10.1186/s13052-025-01933-9 AbstractBackground: Extreme leukocytosis in pertussis is a rare condition, and without effective interventions to reduce white

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Right Atrial Dysfunction Is Prevalent in Pediatric Acute Respiratory Distress Syndrome and Reflects Pulmonary Hypertension and Right Ventricular Dysfunction

Nathan D. Markiewitz, Yan Wang, Robert A. Berg, Nadir Yehya, Celeste Dixon, Laura Mercer-Rosa, Adam S. HimebauchChildren’s Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania. United States Critical Care ExplorationsCrit Care Exp 2025; 7: DOI: 10.1097/CCE.0000000000001230 AbstractImportance: Right atrial (RA) dysfunction is associated with worse outcomes in some populations with pulmonary hypertension

Right Atrial Dysfunction Is Prevalent in Pediatric Acute Respiratory Distress Syndrome and Reflects Pulmonary Hypertension and Right Ventricular Dysfunction Read More »

Management of Obstructed Complete Left Partial Anomalous Pulmonary Venous Return in a Preterm Infant

Timothy R. Harris, Joiliana Lecointe, Thomas P. Doyle, Nhue L. Do, Dana R. Janssen, Garrett N. CoyanVanderbilt University Medical Center. University of Arizona. Meharry Medical College.United States Annals of Thoracic Surgery Short ReportsAnn Thorac Surg Short Rep 2025; 3: 106-108DOI: 10.1016/j.atssr.2024.09.006 AbstractA 25-week preterm neonate was born with complete left-sided partial anomalous pulmonary venous drainage with

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Macitentan: Pediatric First Approval

Susan J. KeamSpringer Nature.New Zealand Paediatric DrugsPaediatr Drugs 2025; DOI: 10.1007/s40272-025-00692-8 AbstractMacitentan (Opsumit®), an endothelin receptor antagonist (ERA) developed by Johnson & Johnson, is well established worldwide as monotherapy or combination therapy for the long-term treatment of pulmonary arterial hypertension (PAH). In September 2024, based on phase 3 clinical data in patients aged < 18 years,

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A maternal hypoxia mouse model to study the effect of late gestational hypoxia on offspring lung outcomes

Thi-Tina N. Nguyen, Caitlin V. Lewis, Daniel Colon Hidalgo, Janelle N. Posey, Mariah Jordan, Timothy E. Porfilio, Maya R. Grayck, Clyde J. Wright, Cassidy Delaney, Eva S. NozikUniversity of Colorado Anschutz Medical Campus. United States Frontiers in PhysiologyFront Physiol 2025; 16: DOI: 10.3389/fphys.2025.1513703 AbstractExtremely preterm birth predisposes infants to bronchopulmonary dysplasia and associated pulmonary hypertension (PH).

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Concurrent Bronchopulmonary Sequestration in Congenital Diaphragmatic Hernia: Is Frequency Increasing or Are We Better at Diagnosis?

Michelle J. Yang, Christian C. Yost, Martha Monson, Paula J. Woodward, Anne M. Kennedy, Stephen J. Fenton, Katie W. Russell, Janice L. B. Byrne, Bradley A. YoderPrimary Children’s Hospital and University of Utah School of Medicine.United States Journal of Pediatrics: Clinical PracticeJ Pediatr Clin Pract 2025; DOI: 10.1016/j.jpedcp.2025.200141 AbstractObjective: To assess the incidence and clinical outcomes of

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Recanalization and interventional stenting of a closed ductus arteriosus in pulmonary hypertension associated with von Hippel-Lindau disease: a case report

Emine Gülsah Torun, Denizhan Bagrul, Ibrahim EceAnkara Bilkent City Hospital.Turkey Cardiology in the YoungCardiol Young 2025; DOI: 10.1017/S1047951125001374 AbstractPulmonary arterial hypertension remains a progressive, life-threatening condition despite advances in medical treatments. We report the first case of the interventional creation of a reverse Potts shunt by stenting a closed ductus arteriosus in a four-year-old child with

Recanalization and interventional stenting of a closed ductus arteriosus in pulmonary hypertension associated with von Hippel-Lindau disease: a case report Read More »

Differences in Pulmonary Artery Stiffness Measured by CMR in Preterm-Born Young Adults With and Without Bronchopulmonary Dysplasia

Wouter J. van Genuchten, Jarno J. Steenhorst, Gabrielle M. J. W. van Tussenbroek, Nikki van der Velde, Lieke S. Kamphuis, Irwin K. M. Reiss, Daphne Merkus, Willem A. Helbing, Alexander HirschErasmus MC. University Hospital Munich.Netherlands and Germany Circulation Cardiovascular ImagingCirc Cardiovasc Imaging 2025; DOI: 10.1161/CIRCIMAGING.124.017791 AbstractBackground: Very preterm-born infants are at risk for developing bronchopulmonary dysplasia (BPD), a chronic lung disease. Nowadays, the majority of these infants reach adulthood.

Differences in Pulmonary Artery Stiffness Measured by CMR in Preterm-Born Young Adults With and Without Bronchopulmonary Dysplasia Read More »

A machine learning approach to predict mortality and neonatal persistent pulmonary hypertension in newborns with congenital diaphragmatic hernia. A retrospective observational cohort study

Luana Conte, Ilaria Amodeo, Giorgio De Nunzio, Genny Rafaeli, Irene Borzani, Nicola Persico, Alice Griggio, Giuseppe Como, Mariarosa Colnaghi, Monica Fumagalli, Donato Cascio, Giacomo CavallaroUniversità Degli Studi Di Palermo. Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico. Laboratory of Interdisciplinary Research Applied to Medicine (DReAM). “E. De Giorgi”, University of Salento. Università Degli Studi Di Milano.

A machine learning approach to predict mortality and neonatal persistent pulmonary hypertension in newborns with congenital diaphragmatic hernia. A retrospective observational cohort study Read More »

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