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Beyond classical collagen: basement membrane collagen IV in age-associated lung diseases

Natalia El-Merhie, Claudia A. Staab-Weijnitz, Janette K. Burgess, Grazyna KwapiszewskaJustus Liebig University. University of Colorado Anschutz Medical Campus. University of Groningen, andUniversity Medical Center Groningen. Medical University of Graz. Germany, United States, Netherlands, Austria European Respiratory ReviewsEur Respir Rev 2025; 34: DOI: 10.1183/16000617.0192-2024 AbstractChronic lung diseases such as COPD, asthma, idiopathic pulmonary fibrosis (IPF) and pulmonary […]

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Response to two Janus kinase inhibitors in a boy with SAVI during 2-year follow-up: case report and literature review

Yiting Chen, Wenhe Zang, Haoyuan Zhong, Xianqin Deng, Wenting Zhong, Lianyu Wang, Xinying ChenSecond Affiliated Hospital of Guangzhou University of Chinese Medicine and Guangdong Provincial Hospital of Chinese Medicine.China Frontiers in ImmunologyFront Immunol 2025; 15: DOI: 10.3389/fimmu.2025.1615075 AbstractSTING-associated vasculopathy with onset in infancy (SAVI) represents an identified rare type I interferonopathy, triggered by gain-of-function mutations in

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Outcomes of extremely preterm infants with bronchopulmonary dysplasia: a retrospective cohort study

Ashraf Gad, Rowan Mesilhy, Thomas Maveli, FatimaAli, Noora Jasim, MalazAdam, Tasneim Abdalla, Mohamed Madani, Mohammad Ayman Alkhateeb, Mohammad A. A. BayoumiHamad Medical Corporation. Qatar University. Sidra Medicine. Qatar Scientific ReportsSci Rep 2025; 15: DOI: 10.1038/s41598-025-12066-8 AbstractTo investigate the respiratory and related health outcomes at 18 months for extremely preterm (EP) infants diagnosed with bronchopulmonary dysplasia (BPD).

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Distinctive hemodynamic phenotype in Fontan-type circulation patients with distal esophageal varices

Luis Téllez, Luis, María Toledano, María Álvarez, Elvira Garrido-Lestache, Elena Garrido, Antonio Guerrero, Jesús Donate, Lorenzo Canova, María Torres, Cristian Perna, María Jesús del Cerro, Agustín AlbillosHospital Universitario Ramón y Cajal, IRYCIS, CIBERehd, Universidad de Alcalá. Spain HepatologyHepatology 2025;  DOI: 10.1097/HEP.0000000000001472 AbstractBackground aims: Esophageal varices (EV) are common in adults with Fontan-type circulation and may arise via

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Fetal left pulmonary artery-to-left atrial fistula with aplasia of the left lung: successful postnatal transcatheter closure

Bilgehan Betül Biçer, Hayrettin Hakan Aykan, Tevfik Karagöz, Ercan TutarHacettepe University and a Private Clinic.Turkey Cardiology in the YoungCardiol Young 2025; DOI: 10.1017/S1047951125001714 AbstractIntroduction: In the presence of fetal cardiomegaly, when there is no cardiac malformation or dysfunction, systemic or pulmonary arteriovenous malformations that may cause volume loading should be sought. We aimed to present a fetus

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A large pulmonary arteriovenous malformation in an adolescent girl – timely diagnosis and treatment: a case report

Shilpa Krishnapura Lakshiminarayana, Bangalore Srinivas Pranathi, Dhanalakshmi Kumble, Mallesh Kariyappa, Usha Mk SastryVani Vilas Hospital and Bangalore Medical College and Research Institute. Sri Jayadeva Institute of Cardiovascular Sciences and Research.India Paediatrics and International Child HealthPaediatr Int Child Health 2025; DOI: 10.1080/20469047.2025.2515723 AbstractPulmonary arteriovenous malformation (PAVM) is a rare, pathological, intrapulmonary, right-to-left shunt resulting from abnormal communication

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Pediatric Pulmonary Arteriovenous Malformations in Patients with Hereditary Hemorrhagic Telangiectasia: Screening, Diagnosis, and Management

Claire S. Kaufman, Minh Anh Nguyen, Amy Bezold, Mark S. ChesnuttOregon Health and Science University. United States Journal of Clinical MedicineJ Clin Med 2025; 14: DOI: 10.3390/jcm14113739 AbstractPulmonary arteriovenous malformations (PAVMs) are abnormal communications between a pulmonary artery and pulmonary vein that bypass the capillary bed, resulting in right-to-left shunting. The majority of PAVMs are associated

Pediatric Pulmonary Arteriovenous Malformations in Patients with Hereditary Hemorrhagic Telangiectasia: Screening, Diagnosis, and Management Read More »

Ten-Year Experience with Pediatric Pulmonary Vein Interventions: Adverse Events and Institutional Strategies for Safety

Daijo Takajo, Paul J. Critser, Amr Matoq, Sarosh P. Batlivala, Shabana Shahanavaz, Russel HirschCincinnati Children’s Hospital Medical Center. University of Cincinnati College of Medicine. United States Pediatric CardiologyPediatr Cardiol 2025; DOI: 10.1007/s00246-025-03955-w AbstractPulmonary vein stenosis (PVS) in pediatric patients is associated with significant morbidity and requires repeated transcatheter interventions to maintain pulmonary vein patency. While these

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The effectiveness of pulmonary hypertension screening in infants born preterm

Stephanie Vachon, Rajiv Devanagondi, Andrew Dylag, Hongyue Wang, Gloria PryhuberUniversity of Rochester Medical Center. University of Iowa Stead Family Department of Pediatrics. United States Early Human DevelopmentEarly Hum Dev 2025; DOI: 10.1016/j.earlhumdev.2025.106342 AbstractObjective: To determine if pulmonary hypertension (PH) screening in at-risk infants born preterm reduces morbidity and/or NICU length of stay.Study design: This single-center retrospective cohort chart

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c-Myc promotes metabolic reprogramming in pulmonary hypertension via the stimulation of glutaminolysis and the reductive tricarboxylic acid cycle

Manivannan Yegambaram, Xutong Sun, Qing Lu, Alejandro Garcia Flores, Marina Zemskova, Jamie Soto, Adam Rauckhorst, Emin Maltepe, Ting Wang, Jeffrey R. Fineman, Stephen M. BlackHerbert Wertheim College of Medicine and Florida International University. University of California San Francisco. United States Redox BiologyRedox Biol 2025; DOI: 10.1016/j.redox.2025.103765 AbstractEndothelial cell (EC) dysfunction is key in initiating and progressing

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