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Inhibiting Serotonin Synthesis for the Treatment of Pulmonary Arterial Hypertension

Georg Hansmann, Michael BaderFriedrich-Alexander-University Erlangen-Nürnberg. Trypto Therapeutics. Charité-Universitätsmedizin. University of LübeckGermany Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70100 AbstractAbstract Not Available CategoryMedical Therapy. Efficacy or Lack of EfficacyMedical Therapy. Adverse Effects or Lack of Adverse Effects Age Focus: No Age-Related Focus Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication Article Access Free […]

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Embolization of Acquired Pulmonary Arteriovenous Malformations Resulting from Metastatic Gestational Trophoblastic Neoplasia

Gretchen A. Ferber, Sarah Khoncarly, James J. Buchino, Janice D. McDanielUniversity of Pittsburgh Medical Center. Case Western Reserve University MetroHealth Medical Center. Cleveland Clinic Akron General Hospital. Akron Children’s Hospital.United States Journal of Vascular and Interventional RadiologyJ Vasc Interv Radiol 2020; 31: 1890-1892DOI: 10.1016/j.jvir.2020.01.021 AbstractAbstract Not Available CategoryPulmonary Arteriovenous Malformations Age Focus: Pediatric Pulmonary Vascular Disease

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The clinical and genetic features of hereditary haemorrhagic telangiectasia (HHT) in central South Africa-three novel pathogenic variants

Tendaishe T. Mutize, Riaz Y. Seedat, Johannes K. Ploos van Amstel, Johannes J. Mager, Stephen C. Brown, Fekade Gebremariam, Marius J. CoetzeeUniversity of the Free State nd Universitas Academic Hospital. Utrecht University. Shelly Beach Hospital. National Health Laboratory Service.South Africa and Netherlands Molecular Biology ReportsMol Biol Rep 2020; 47: 9967-9972DOI: 10.1007/s11033-020-05985-4 AbstractHereditary haemorrhagic telangiectasia (HHT) is

The clinical and genetic features of hereditary haemorrhagic telangiectasia (HHT) in central South Africa-three novel pathogenic variants Read More »

Comparative study between nebulized and intravenous magnesium sulfate for treatment of persistent pulmonary hypertension in neonates

Nashwa Farouk Mohamed, Osama Abu El Fetouch Zaki El Feky, Heba Morsy Saad El Din El Ganady, Walid Abd Elatif Abd El HalimBenha University.Egypt Journal of Neonatal-Perinatal MedicineJ Neonatal Perinatal Med 2025; 18: 246-254DOI: 10.1177/19345798251325510 AbstractBackground: Persistent pulmonary hypertension of the newborn (PPHN) is a life-threatening condition resulting from elevated pulmonary vascular resistance, causing severe hypoxemia.

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Pulmonary arteriole narrowing in end-stage cystic fibrosis lungs occurs with and without small airway disease

Astrid Vermaut, Gitte Aerts, Lynn Willems, Vincent Geudens, Charlotte Hooft, Pieterjan Kerckhof, Lise Vanvuchelen, Marta Zapata-Ortega, Hanne Beeckmans, Xin Jin, Yousry Mohamady, Jan Van Slambrouck, Lucia Aversa, Janne Verhaegen, Emanuela E. Cortesi, Charlotte De Fays, Birgit Weynand,Dirk E. Van Raemdonck, Laurens J. Ceulemans, Wim A. Wuyts, Marianne Carlon, Robin Vos, Natalie Lorent, Ghislaine Gayan-Ramirez, Laurent

Pulmonary arteriole narrowing in end-stage cystic fibrosis lungs occurs with and without small airway disease Read More »

A rare cause of newborn central cyanosis

Anna Waldoch, Robert Sabiniewicz, Joanna KwiatkowskaMedical University in Gdansk.Poland EchocardiographyEchocardiography 2020; 37: 1524-1525DOI: 10.1111/echo.14809 AbstractPulmonary arteriovenous malformations are rare congenital vascular anomalies. They are usually associated with congenital hemorrhagic hemangioma. The hemodynamic effect of fistulas depends on their size, as well as the location. The most common manifestations include central cyanosis, ischemic stroke, murmur over the

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Deficiency of arginase2 attenuates hyperoxia-induced inflammation and airway hyperreactivity in neonatal mice

Yi Jin, Bernadette Chen, Yusen Liu, Leif D. NelinNationwide Children’s Hospital and Ohio State University.United States American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2025; DOI: 10.1152/ajplung.00202.2024 AbstractBronchopulmonary dysplasia (BPD) is a common chronic lung disease in pediatrics. Neonatal mice placed in hyperoxia (85% oxygen, HYP) develop lung injury

Deficiency of arginase2 attenuates hyperoxia-induced inflammation and airway hyperreactivity in neonatal mice Read More »

Restoration of pp60Src Re-Establishes Electron Transport Chain Complex I Activity in Pulmonary Hypertensive Endothelial Cells

Manivannan Yegambaram, Marissa D. Pokharel, Xutong Sun, Qing Lu, Jamie Soto, Saurabh Aggarwal, Emin Maltepe, Jeffery R. Fineman, Ting Wang, Stephen M. BlackFlorida International University. University of California San Francisco. United States International Journal of Molecular SciencesInt J Mol Sci 2025; 26: DOI: 10.3390/ijms26083815 AbstractIt is well-established that mitochondrial dysfunction plays a critical role in the

Restoration of pp60Src Re-Establishes Electron Transport Chain Complex I Activity in Pulmonary Hypertensive Endothelial Cells Read More »

Vascular EC-SOD limits the accumulation, proinflammatory profibrotic reprogramming, and hyaluronan binding of interstitial macrophages in hypoxia

Caitlin V. Lewis, Thi-Tina N. Nguyen, Timothy Porfilio, Samuel D. Burciaga, Janelle N. Posey, Mariah Jordan, Daniel Colon Hidalgo, Kurt R. Stenmark, Claudia Mickael, Christina Sul, Rebecca E. Oberley-Deegan, Cassidy Delaney, Eva S. NozikUniversity of Colorado, University of Colorado Anschutz Medical Campus and Children’s Hospital Colorado. University of Nebraska Medical Center.United States American Journal of

Vascular EC-SOD limits the accumulation, proinflammatory profibrotic reprogramming, and hyaluronan binding of interstitial macrophages in hypoxia Read More »

Congenital portosystemic shunts: diagnosis and treatment

Stéphanie Franchi-Abella, Emmanuel Gonzales, Oanez Ackermann, Sophie Banchereau, Daniéle Pariente, Florent Guérin, International Registry of Congenital Poertosystemic Shunt MembersHôpital Bicêtre, Hôpitaux Universitaire Paris-Sud and Assistance Publique Hôpitaux de Paris. National Reference Centre for Rare Pediatric Liver Diseases and Filfoie. University Paris -Sud. France Abdominal RadiologyAbd Radiol 2018; 43: 2023-2036DOI: 10.1007/s00261-018-1619-8 AbstractCongenital portosystemic shunts (CPSS) are rare

Congenital portosystemic shunts: diagnosis and treatment Read More »

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