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Decreased endothelial cell retinoic acid signaling accelerates progression of single ventricle pulmonary arteriovenous malformations

Henry Rousseau, Tina Wan, Nhi Nguyen, Jaime Wendt Andrae, Michael Tschannen, Angela J. Mathison, Victor Jin, Olivia Groh, Xingyan Zhou, Stryder M. Meadows, Ramani Ramchandran,Igor Shmarakov, Amy Y. Pan, Andrew D. SpearmanMedical College of Wisconsin and Children’s Wisconsin. Rutgers University. Tulane University. United States bioRxivbioRxiv 2025; DOI: 10.64898/2025.12.08.693095 AbstractBackground: Pulmonary arteriovenous malformations (PAVMs) are vascular complications that

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Effects of altitude and exercise on pulmonary capillary integrity: evidence for subclinical high-altitude pulmonary edema

Marlowe W. Eldridge, Ruedi K. Braun, Ken Y. Yoneda, William F. WalbyUniversity of Wisconsin.United States Journal of Applied PhysiologyJ Appl Physiol 2006; 100: 972-980 DOI: 10.1152/japplphysiol.01048.2005 AbstractStrenuous exercise may be a significant contributing factor for development of high-altitude pulmonary edema, particularly at low or moderate altitudes. Thus we investigated the effects of heavy cycle ergometer exercise (90%

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Interventions for preventing high altitude illness: Part 2. Less commonly-used drugs

Alejandro G Gonzalez Garay, Daniel Molano Franco, Víctor H Nieto Estrada, Arturo J Martí-Carvajal, Ingrid Arevalo-RodriguezNational Institute of Pediatrics.Mexico Cochrane Database of Systemic ReviewsCochrane Database Syst Rev 2018; 3: DOI: 10.1002/14651858.CD012983 AbstractBackground: High altitude illness (HAI) is a term used to describe a group of mainly cerebral and pulmonary syndromes that can occur during travel to elevations

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Pulmonary hemodynamics in children living at high altitudes

Dante Penaloza, Francisco Sime, Luis RuizUniversity Cayetano Heredia.Peru High Altitude Medicine and BiologyHigh Altit Med Biol 2008; 9: 199-207DOI: 10.1089/ham.2008.1004 AbstractThere are numerous publications on altitude-related diseases in adults. In addition, an International Consensus Statement published in 2001 deals with altitude-related illnesses occurring in lowland children who travel to high altitudes. However, despite the millions of

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Right ventricular adaptation in congenital heart disease: Does the type of right ventricular overload matter?

Renee S. Joosen, Gregor J. Krings, Heleen B. van der Zwaan, Nefise Karaman, Marco Guglielmo, Lucas R. Celant, Marco J. W. G€otte, Michael G. Dickinson, Michiel Voskuil, Marielle C. van de Veerdonk, Johannes M. P. J. BreurUniversity Medical Center Utrecht. Amsterdam University Medical Center and University of Amsterdam. Netherlands Journal of Thoracic and Cardiovascular Surgery

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Neonatologist-Performed Echocardiography in Neonatal Pulmonary Hypertension: A Narrative Review of the Literature

Anna Chiara Titolo, Mandy Ferrocino, Eleonora Biagi, Luisa Rizzo, Hajrie Seferi, Valentina Dell’Orto, Serafina Perrone, Susanna EspositoParma University Hospital and University of Parma.Italy DiagnosticsDiagnostics 2025; 15: DOI: 10.3390/diagnostics15243154 AbstractNeonatal pulmonary hypertension (PH) is a major cause of illness and death in newborns. Neonatologist-performed echocardiography (NPE) is increasingly used as a bedside tool to assess heart function,

Neonatologist-Performed Echocardiography in Neonatal Pulmonary Hypertension: A Narrative Review of the Literature Read More »

Construction of an early diagnostic model for pulmonary hypertension based on aging-related signature genes and identification of potential therapeutic targets

MengzeWang, Jiafei Lu, Xinyu Li, Huating Xie, Junjie Liang, Jun Luo, Xishu Deng, Guoquan Pan, Bowen Ji, Xiaojie DingKunming Children’s Hospital. Southern Medical University. Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University. Taizhou Central Hospital (Taizhou University Hospital). Second Hospital of Jiaxing and Second Affiliated Hospital of Jiaxing University. Zhejiang Rongjun Hospital.

Construction of an early diagnostic model for pulmonary hypertension based on aging-related signature genes and identification of potential therapeutic targets Read More »

Child health and living at high altitude

Susan Niermeyer, P. Andrade Mollinedo, L. HuichoUniversity of Colorado School of Medicine and Children’s Hospital of Colorado. Caja Nacional de Salud and Clínica del Sur and Clínica Alemana. Universidad Nacional Mayor de San Marcos and Universidad Peruana Cayetano Heredia.United States, Bolivia and Peru Archives of Disease in ChildrenArch Dis Child 2009; 94: 806-811DOI: 10.1136/adc.2008.141838 AbstractThe health of

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Clinical manifestations and long-term follow-up in pediatric patients living at altitude with isolated pulmonary artery of ductal origin

Shinichi Takatsuki, Jeffrey Darst, Bibhuti B. Das, Thomas E. Fagan, Robert Wolfe, David Dunbar IvyChildren’s Hospital Colorado and University of Colorado Denver.United States Pediatric CardiologyPediatr Cardiol 2012; 33: 775-781DOI: 10.1007/s00246-012-0213-z AbstractThis study’s aim was to define the clinical manifestations and long-term outcome of pediatric patients living at altitude with isolated pulmonary artery (PA) of ductal origin

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Pediatric Lung Transplantation in Israel: 29 Cases from a Single Center’s Experience

Eyal Jacobi, Moshe Heching, Osnat Shtraichman, Dror Rosengarten, Barak Pertzov, Ophir Bar-On, Hagit Levine, Ofer Schiller, Yury Peysakhovich, Dario Prais, Yaron Barac, Mordechai Reuven KramerSchneider Children’s Medical Center, Rabin Medical Center, Gray Faculty of Medical and Health Sciences and Tel Aviv University. Israel Israel Medical Association JournalIsrael Med Assoc J 2025; 27: 778-782DOI: Not Available

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