All Categories Archives - Page 52 of 208

Deficiency of the Deubiquitinase UCHL1 Attenuates Pulmonary Arterial Hypertension

Haiyang Tang, Akash Gupta, Seth A. Morrisroe, Changlei Bao, Tae-Hwi Schwantes-An, Geetanjali Gupta, Shuxin Liang, Yanan Sun, Aiai Chu, Ang Luo, Venkateswaran Ramamoorthi Elangovan, Shreya Sangam, Yinan Shi, Samisubbu R. Naidu, Jia-Rong Jheng, Sultan Ciftci-Yilmaz, Noel A. Warfel, Louise Hecker, Sumegha Mitra, Anna W. Coleman, Katie A. Lutz, Michael W. Pauciulo, Yen-Chun Lai, Ali Javaheri, […]

Deficiency of the Deubiquitinase UCHL1 Attenuates Pulmonary Arterial Hypertension Read More »

ECMO Bridge to Lung Transplant in Children with Idiopathic Pulmonary Arterial Hypertension

Hosam F. Ahmed, David L. S. Morales, Don Hayes, JrCincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine.United States LungLung 2024; DOI: 10.1007/s00408-024-00703-4 AbstractIdiopathic pulmonary arterial hypertension (IPAH) represents an important clinical indication for lung transplant (LTx) in children. Recent trends show fewer children with IPAH are undergoing LTx nowadays compared to previous

ECMO Bridge to Lung Transplant in Children with Idiopathic Pulmonary Arterial Hypertension Read More »

Pediatric Lung Transplantations: New Possibilities and Challenges in Treatment of Children With End-Stage Respiratory Failure

Marek Ochman, Dagmara Galle, Agnieszka Goryczka, Alicja Gałeczka-Turkiewicz, Fryderyk Zawadzki, Karol Chorazy, Tomasz Stacel, Maciej Urlik, Tomasz HrapkowiczMediacl University of Silesia in Katowice. Medical University of Vienna.Poland and Austria Transplantation ProceedingsTransplant Proc 2024; DOI: 10.1016/j.transproceed.2024.03.017 AbstractIntroduction: Lung transplantation (LTx) is the last treatment option for children with end-stage respiratory failure. According to the literature, cystic fibrosis remains

Pediatric Lung Transplantations: New Possibilities and Challenges in Treatment of Children With End-Stage Respiratory Failure Read More »

Pediatric Pulmonary Hypertension

Raysa Morales-Demori, Ryan Coleman, George B. MalloryTexas Children’s Hospital and Baylor College of Medicine.United States Pediatrics in ReviewPediatr Rev 2024; 45: 251-259DOI: 10.1542/pir.2023-006010 AbstractAbstract Not Available CategoryReview Articles Concerning Pulmonary Vascular Disease Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication Article Access Free PDF File or

Pediatric Pulmonary Hypertension Read More »

Single cell transcriptomic analyses reveal diverse and dynamic changes of distinct populations of lung interstitial macrophages in hypoxia-induced pulmonary hypertension

Sushil Kumar, Claudia Mickael, Rahul Kumar, Ram Raj Prasad, Nzali V. Campbell, Hui Zhang, Min Li, B. Alexandre McKeon, Thaddeus E. Allen, Brian B. Graham, Yen-Rei A. Yu, Kurt R. StenmarkUniversity of Colorado School of Medicine. University of California San Francisco. Zuckerberg San Francisco General Hospital.United States Frontiers in ImmunologyFront Immunol 2024; 15: DOI: 10.3389/fimmu.2024.1372959 AbstractIntroduction: Hypoxia

Single cell transcriptomic analyses reveal diverse and dynamic changes of distinct populations of lung interstitial macrophages in hypoxia-induced pulmonary hypertension Read More »

Successful Atrial Septal Defect Closure Subsequent to Medical Pulmonary Preconditioning in an Infant With Severe Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia

Maki Sato, Hirofumi Saiki, Kanchi Saito, Akira Sato, Seiko Kuwata, Satoshi Nakano, Junichi Koizumi, Kotaro Oyama, Manami AkasakaIwate Medical University. Michinoku Medical Center on Disability and Health.Japan CureusCureus 2024; 16: DOI: 10.7759/cureus.57290 AbstractWhile atrial septal defect (ASD) may contribute to right ventricular decompression in patients with severe pulmonary hypertension (PH), the pulmonary vasculature might be compromised

Successful Atrial Septal Defect Closure Subsequent to Medical Pulmonary Preconditioning in an Infant With Severe Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia Read More »

The Xanthine Derivative KMUP-1 Inhibits Hypoxia-Induced TRPC1 Expression and Store-Operated Ca2+ Entry in Pulmonary Arterial Smooth Muscle Cells

Zen-Kong Dai, Yi-Chen Chen, Su-Ling Hsieh, Jwu-Lai Yeh, Jong-Hau Hsu, Bin-Nan WuKaohsiung Medical University and Kaohsiung Medical University Hospital. Taiwan PharmaceuticalsPharmaceuticals 2024; 17:DOI: 10.3390/ph17040440 AbstractExposure to hypoxia results in the development of pulmonary arterial hypertension (PAH). An increase in the intracellular Ca2+ concentration ([Ca2+]i) in pulmonary artery smooth muscle cells (PASMCs) is a major trigger for pulmonary

The Xanthine Derivative KMUP-1 Inhibits Hypoxia-Induced TRPC1 Expression and Store-Operated Ca2+ Entry in Pulmonary Arterial Smooth Muscle Cells Read More »

Duct Stenting in Duct-Dependent Systemic Blood Flow, Past, Present, and Future

Dietmar SchranzUniversity Clinic Frankfurt and Johann-Wolfgang-Goethe University Clinic.Germany Pediatric CardiologyPediatr Cardiol 2024;DOI: 10.1007/s00246-024-03492-y AbstractArterial duct stenting, pioneered in the early 1990s for newborns with a duct-dependent pulmonary and systemic circulation, has evolved significantly over the past decades. This progressive technique has led to the development of novel therapeutic strategies, including the Hybrid approach introduced three decades

Duct Stenting in Duct-Dependent Systemic Blood Flow, Past, Present, and Future Read More »