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Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990-2021): results from the global burden of disease study

Lili Deng, Jingxuan Xiong, Jiaoli Xu, Qinhong Li, Zugen ChengKunming Children’s Hospital. First Affiliated Hospital of Kunming Medical University. China Frontiers in PediatricsFront Pediatr 2025; DOI: 10.3389/fped.2025.1527281 AbstractIntroduction: Pediatric pulmonary arterial hypertension (PAH) is a rare and severe disorder characterized by obstructive vascular changes that can lead to right heart failure. The clinical presentation and underlying causes […]

Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990-2021): results from the global burden of disease study Read More »

Adaptation of ACMG/AMP Guidelines for Clinical Classification of BMPR2 Variants in Pulmonary Arterial Hypertension Resolves Variants of Unclear Pathogenicity in ClinVar

Christina A. Eichstaedt, Gabriel Maldonado-Velez, Rajiv D. Machado, Stefan Gräf, Dennis Dooijes, Srimmitha Balachandar, Florence Coulet,Kristina Day, Melanie Eyries, Daniela Macaya, Memoona Shaukat, Laura Southgate, Jair Tenorio-Castano, Wendy K. Chung, Carrie L. Welch, Micheala A. AldredThoraxklinik-Heidelberg gGmbH, Heidelberg University Hospital and Translational Lung Research Center (TLRC), German Center for Lung Research (DZL).  Indiana University School

Adaptation of ACMG/AMP Guidelines for Clinical Classification of BMPR2 Variants in Pulmonary Arterial Hypertension Resolves Variants of Unclear Pathogenicity in ClinVar Read More »

Initial Survival and Short-term Pulmonary Comorbidities in Infants with Congenital Diaphragmatic Hernia of Differing Indices of Social Determinants of Health

Yeu Sanz Wu, Alysala Malik, Chunhui Wang, Christian Welch, Caitlin J. Cain-Trivette, Christopher Nemeh, Nicholas Schmoke, Paul Kurlansky, Usha S. Krishnan, Avila De, Vincent Duron Columbia University Irving Medical Center/NewYork Presbyterian Morgan Stanley Children’s Hospital and Columbia University Vagelos College of Physicians & Surgeons. United States Journal of Pediatric SurgeryJ Pediatr Surg 2025; DOI: 10.1016/j.jpedsurg.2025.162460 AbstractPurpose: To

Initial Survival and Short-term Pulmonary Comorbidities in Infants with Congenital Diaphragmatic Hernia of Differing Indices of Social Determinants of Health Read More »

Variability in Home Oxygen Therapy Practices for Bronchopulmonary Dysplasia in Japan: A Questionnaire Survey

Ryo Ogawa, Masaki Hasebe, Tomohiko Nakamura, Fumihiko NambaNagano Children’s Hospital. Saitama Medical Center and Saitama Medical University.Japan Journal of Paediatrics and Child HealthJ Paediatr Child Health 2025; DOI: 10.1111/jpc.70150 AbstractAim: To examine variations in home oxygen therapy (HOT) initiation and management practices for bronchopulmonary dysplasia (BPD) among perinatal medical centres in Japan.Methods: A questionnaire survey was distributed to

Variability in Home Oxygen Therapy Practices for Bronchopulmonary Dysplasia in Japan: A Questionnaire Survey Read More »

Predicting Outcomes in Pediatric Intraluminal Pulmonary Vein Stenosis Using a Comprehensive Standardized Catheterization Assessment: A Prospective Study

Ryan Callahan, Kimberlee Gauvreau, Mirjam Keochakian, Jesse J. Esch, Diego Porras, Lisa Bergersen, Rebecca Beroukhim, Michael Farias, David M. Harrild, Christina M. Ireland, Neha Kwatra, Kathy J. JenkinsChildren’s Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine. Boston Children’s Hospital and Harvard Medical School. United States Circulation Cardiovascular InterventionsCirc Cardiovasc Interv 2025; DOI: 10.1161/CIRCINTERVENTIONS.124.015002

Predicting Outcomes in Pediatric Intraluminal Pulmonary Vein Stenosis Using a Comprehensive Standardized Catheterization Assessment: A Prospective Study Read More »

Biventricular electromechanical dysfunction and molecular remodeling in a rat model of advanced pulmonary arterial hypertension

Francesco Paolo Lo Muzio, Alessia Caputo, Rosario Statello, Mirko Hu, Roberta Maestri, Giovanna Pelà, Aderville Cabassi, Margherita Burattini, Giacomo Rozzi, Silvia Berrettoni, Barbara Montanini, Stefano Rossi, Lorenzo Fassina, Giovanni Battista Luciani, Gianluigi Condorelli, Michele MiragoliUniversity of Parma. Deutsches Herzzentrum Der Charité, Campus Virchow-Klinikum. University of Verona. University of Pavia. IRCCS Humanitas Research Hospital. Italy and

Biventricular electromechanical dysfunction and molecular remodeling in a rat model of advanced pulmonary arterial hypertension Read More »

Persistent Pulmonary Hypertension of the Newborn in Very Low Birth Weight Infants: Risk Factors and Clinical Outcomes from a Matched Case-Control Study

Anucha Thatrimontrichai, Pattima Pakhathirathien, Manapat Praditaukrit, Gunlawadee Maneenil, Supaporn Dissaneevate, Ploypailin Jantarawongpisal, Jenjira SaechanPrince of Songkla University.Thailand Journal of Clinical MedicineJ Clin Med 2025; 14: DOI: 10.3390/jcm14134759 AbstractBackground/Objectives: To identify the risk factors and clinical outcomes of persistent pulmonary hypertension of the newborn (PPHN) in very low birth weight (VLBW) infants in a resource-limited setting. Methods: We

Persistent Pulmonary Hypertension of the Newborn in Very Low Birth Weight Infants: Risk Factors and Clinical Outcomes from a Matched Case-Control Study Read More »

Mortality Risk Factors and Survival Outcomes in Infants with Persistent Pulmonary Hypertension of the Newborn

Kokaew Chuaikaew, Gunlawadee Maneenil, Anucha Thatrimontrichai, Supaporn Dissaneevate, Manapat PraditaukritPrince of Songkla University.Thailand Journal of Clinical MedicineJ Clin Med 2025; 14: DOI: 10.3390/jcm14134502 AbstractBackground/Objectives: Persistent pulmonary hypertension of the newborn (PPHN) is characterized by increased pulmonary vascular resistance, resulting in severe hypoxemia. This study determined the factors associated with increased risk of mortality and survival rate

Mortality Risk Factors and Survival Outcomes in Infants with Persistent Pulmonary Hypertension of the Newborn Read More »

Computed Tomography Angiography in Pediatric Pulmonary Hypertension: Evaluating MPA-to-Aortic Ratios as Diagnostic Markers

Ali Nazım Güzelbag, Serap Ba, Demet Kangel, Muhammet Hamza Halil Toprak, Ahmet Saki Oguz, Selin Saglam, Ibrahim Cansaran Tanıdır, Erkut ÖzturkSaglik Bilimleri University and Basaksehir Cam and Sakura City Hospital. Turkey DiagnosticsDiagnostics 2025; 15: DOI: 10.3390/diagnostics15131614 AbstractBackground: Pulmonary hypertension (PHT) is a rare but serious condition in children, requiring early diagnosis to prevent right ventricular failure. Non-invasive

Computed Tomography Angiography in Pediatric Pulmonary Hypertension: Evaluating MPA-to-Aortic Ratios as Diagnostic Markers Read More »

Allergy and atopic phenotype are associated with earlier gestation and severity of respiratory symptoms in bronchopulmonary dysplasia

Brianna C. Aoyama, Joseph M. Collaco, Amit Agarwal, Gangaram Akangire, Eric D. Austin, Manvi Bansal, Anita Bhandari, A. Ioana Critea, Lystra P. Hayden, Jonathan C. Levin, Winston M. Manimtim, Audrey N. Miller, Paul E. Moore, Antonia P. Popova, Lawrence M. Rhein, Catherine A. Sheils, Steven H. Abman, Christopher D. Baker, Sara K. Dawson, Mehtap Haktanir

Allergy and atopic phenotype are associated with earlier gestation and severity of respiratory symptoms in bronchopulmonary dysplasia Read More »

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