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Deep Learning Based Prediction of Pulmonary Hypertension in Newborns Using Echocardiograms

Hanna Ragnarsdottir, Ece Ozkan, Holger Michel, Kieran Chin-Cheong, Laura Manduchi, Sven Wellmann, Julia E. VoETH Zurich. Massachusetts Institute of Technology. University Children’s Hospital Regensburg (KUNO), Hospital St. Hedwig of the Order of St. John and University of Regensburg.Switzerland, United States and Germany International Journal of Computer VisionInt J Comput Vis 2024; 132: 2567–2584DOI: 10.1007/s11263-024-01996-x AbstractPulmonary hypertension […]

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Post-treatment with Resolvin D1 attenuates pulmonary hypertension by inhibiting endothelial-to-mesenchymal transition

Xinyu Lia, Hui Li, Bo Feng, Xiaoyan Chen, Ting Chen, Jiafei Lu, Huating Xie, Nana Su, Houlin Chen, Chenghao Lou, Runxin Zhuang, Xi Chen, Shengwei Jin, Yu HaoSecond Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University. Ruijin Hospital and Shanghai Jiao Tong University School of Medicine. China Biomedicine and PharmacotherapyBiomed Pharmacother 2024; DOI: 10.1016/j.biopha.2024.117023

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Prognostic Value of Serial Risk Stratification in Adult and Pediatric Pulmonary Arterial Hypertension: A Systematic Review

Chantal Lokhorst, Sjoukje van der Werf, Rolf M. F. Berger, Johannes M. DouwesBeatrix Children’s Hospital, University Medical Center Groningen and University of GroningenNetherlands Journal of the American Heart AssociationJ Am Heart Assoc 2024; DOI: 10.1161/JAHA.123.034151 AbstractBackground: In pulmonary arterial hypertension, it is recommended to base therapeutic decisions on risk stratification. This systematic review aims to report the prognostic value of serial risk

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Identification of endothelial and mesenchymal FOXF1 enhancers involved in alveolar capillary dysplasia

Guolun Wang, Bingqiang Wen, cMinzhe Guo, Enhong Li, Yufang Zhang, Jeffrey A. Whitsett, Vladimir V. KalinichenkoCincinnati Children’s Research Foundation and University of Cincinnati College of Medicine. University of Arizona, College of Medicine, Phoenix Children’s Research Institute and Phoenix Children’s Hospital.United States Nature CommunicationsNat Commun 2024; 15: DOI: 10.1038/s41467-024-49477-6 Abstract Mutations in the FOXF1 gene, a key

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Growth of the Branch Pulmonary Arteries After Employing ‘Shunt-Only’ Strategy for Neonates With Pulmonary Atresia or Stenosis

Eun Seok Choi, Dong-Hee Kim, Bo Sang Kwon, Chun Soo Park, Tae-Jin YunAsan Medical Center and University of Ulsan College of Medicine. Republic of Korea Seminars in Thoracic and Cardiovascular SurgerySemin Thorac Cardiovasc Surg 2021; 33: 1095-1102DOI: 10.1053/j.semtcvs.2021.03.047 AbstractWe sought to determine the impact of juxtaductal stenosis (JDS) on branch pulmonary artery (PA) growth after systemic-to-pulmonary

Growth of the Branch Pulmonary Arteries After Employing ‘Shunt-Only’ Strategy for Neonates With Pulmonary Atresia or Stenosis Read More »

Williams Syndrome and Neonatal Cardiac Surgery for Congenital Single Ventricle

Taylor E. Katt, Robert L. Spicer, Anji T. Yetman, Ali N. Ibrahimiye, James M. Hammel, Jeffrey A. RobinsonUniversity of Nebraska Medical Center and Children’s Hospital and Medical Center.United States Journal of the American College of Cardiology Case ReportsJACC Case Rep 2020; 2: 1716-1719DOI: 10.1016/j.jaccas.2020.05.098 AbstractWilliams syndrome (WS) is an arteriopathic derangement associated with supravalvular aortic stenosis

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Endothelial-to-Mesenchymal Transition in an Hereditary Hemorrhagic Telangiectasia-like Pediatric Case of Multiple Pulmonary Arteriovenous Malformations

Laura Lorente-Herraiz, Angel M. Cuesta, Lucía Recio-Poveda, Luisa M. Botella, Virginia AlbiñanaCentro de Investigaciones Biológicas Margarita Salas, CIB-CSIC. Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER). Universidad Complutense de Madrid. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC).Spain International Journal of Molecular SciencesInt J Mol Sci 2024; 25: DOI: 10.3390/ijms25116163 AbstractPulmonary arteriovenous

Endothelial-to-Mesenchymal Transition in an Hereditary Hemorrhagic Telangiectasia-like Pediatric Case of Multiple Pulmonary Arteriovenous Malformations Read More »

Fibroblasts in Pulmonary Hypertension: Roles and Molecular Mechanisms

Hui Zhang, Min Li, Cheng-Jun Hu, Kurt R. StenmarkUniversity of Colorado School of Medicine and School of Dental Medicine.United States CellsCells 2024; 13: DOI: 10.3390/cells13110914 AbstractFibroblasts, among the most prevalent and widely distributed cell types in the human body, play a crucial role in defining tissue structure. They do this by depositing and remodeling extracellular matrixes

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Echocardiographic Predictors of Ductal Tissue-Related Branch Pulmonary Artery Stenosis in Pulmonary Atresia

Marisha McClean, Deliwe Ngwezi, Timothy Colen, Kandice Mah, Mohammed Al-Aklabi, Lisa HornbergerStollery Children’s Hospital and University of Alberta. Children’s Hospital LHSC and Western University. Canada Pediatric CardiologyPediatr Cardiol 2022; 43: 878-886DOI: 10.1007/s00246-021-02799-4 AbstractBranch pulmonary artery (PA) stenosis due to ductus arteriosus (DA) tissue (DA-PS) contributes to the morbidity associated with pulmonary atresia (PAtr). We sought to

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Preoperative Computed Tomographic Angiography Can Predict Need for Branch Pulmonary Artery Intervention in Patients With Ductal-Dependent Pulmonary Blood Flow

Kirsten Graff, Anthony M. Hlavacek, Nicholas Aizcorbe, Scott M. Bradley, Shahryar M. ChowdhuryMedical University of South Carolina.United States World Journal of Pediatric and Congenital Heart SurgeryWorld J Pediatr Congenit Heart Surg 2023; 14: 275-281DOI: 10.1177/21501351221151050 AbstractBackground: Neonates with ductal-dependent pulmonary blood flow (DD-PBF) are at risk for pulmonary artery (PA) stenosis. The objective of this study was

Preoperative Computed Tomographic Angiography Can Predict Need for Branch Pulmonary Artery Intervention in Patients With Ductal-Dependent Pulmonary Blood Flow Read More »

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