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An intronic variant in TBX4 in a single family with variable and severe pulmonary manifestations

Frances O. Flanagan, Alexander M. Holtz, Sara O. Vargas, Casie A. Genetti, Klaus Schmitz-Abe, Alicia Casey, John C. Kennedy, Benjamin A. Raby, Mary P. Mullen, Martha P. Fishman, Pankaj B. AgrawalBoston Children’s Hospital and Harvard Medical School. University of Miami Miller School of Medicine.United States Nature Partner Journals Genomic MedicineNPJ Genom Med 2023; 8: DOI: 10.1038/s41525-023-00350-3

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Role of Sildenafil in Management of Pediatric Acute Respiratory Distress Syndrome

Monika Janagill, Puneet Aulakh Pooni, Siddharth Bhargava, Shibba Takkar ChhabraDayanand Medical College and Hospital.India Journal of Pediatric Intensive CareJ Pediatr Int Care 2021; 12: 148-153DOI: 10.1055/s-0041-1730900 AbstractAcute respiratory distress syndrome (ARDS) has high mortality and multiple therapeutic strategies have been used to improve the outcome. Inhaled nitric oxide (INO), a pulmonary vasodilator, is used to improve

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Outpatient respiratory outcomes in children with BPD on supplemental oxygen

Julianne R. McGlynn, Brianna C. Aoyama, Amanda Martin, Joseph M. Collaco, Sharon A. McGrath-MorrowChildren’s Hospital of Philadelphia and University of Pennsylvania. Johns Hopkins University School of Medicine.United States Pediatric PulmonologyPediatr Pulmonol 2023; 58: 1535-1541DOI: 10.1002/ppul.26356 AbstractIntroduction: Preterm children with bronchopulmonary dysplasia (BPD) frequently require supplemental oxygen in the outpatient setting. In this study, we sought to determine

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Descriptive images and features of pulmonary vascular disease in a child with a FOXF1 variant

Ronald W. Day, Khanh V. Lai, Hailey N. Baisch, Isabel C. LauUniversity of Utah and Primary Children’s Hospital. St. Luke’s Children’s Treasure Valley Pediatrics. Mountainstar Ogden Pediatrics.United States Pediatric PulmonologyPediatr Pulmonol 2023; DOI: 10.1002/ppul.26480 AbstractNo abstract CategoryClass III. Pulmonary Hypertension Associated with Developmental Diseases of the LungGenetic Factors Associated with Pulmonary Vascular DiseaseDiagnostic Testing for Pulmonary

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Neonatal outcomes in pregnant women with pulmonary arterial hypertension associated with heart disease

Jianglin Ma, Fang Luo, Lingling YanThe First Affiliated Hospital, College of Medicine, Zhejiang University.China Pediatrics and NeonatologyPediatr Neonatol 2023; DOI: 10.1016/j.pedneo.2022.11.008 AbstractBackground: As an increasing number of women with pulmonary arterial hypertension (PAH) choose to become pregnant, outcomes in newborns have become a priority. The main purpose of this study was to compare the neonatal outcomes in

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Inhaled Nitric Oxide Promotes Angiogenesis in the Rodent Developing Brain

Gauthier Loron, Julien Pansiot, Paul Olivier, Christiane Charriaut-Marlangue, Olivier BaudUniversité de Reims Champagne-Ardenne. Université Paris Cité. Children’s University Hospital of Geneva.France and Switzerland International Journal of Molecular SciencesInt J Mol Sci 2023; 24: DOI: 10.3390/ijms24065871 AbstractInhaled nitric oxide (iNO) is a therapy used in neonates with pulmonary hypertension. Some evidence of its neuroprotective properties has been

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Inhaled nitric oxide in preterm neonates with preterm prelabour rupture of membranes, a systematic review

Rachel Mullaly, Naomi McCallion, Afif El-KhuffashThe Rotunda Hospital. University of Southampton. Royal College of Surgeons of Ireland.Ireland and United Kingdom Acta PediatricaActa Pediar 2023; 112: 358-371DOI: 10.1111/apa.16596 AbstractAim: To perform a systematic literature review to determine the effect of inhaled nitric oxide (iNO) on oxygenation, mortality and morbidity in preterm neonates with preterm prelabour rupture of membranes

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Novel FOXF1-Stabilizing Compound TanFe Stimulates Lung Angiogenesis in Alveolar Capillary Dysplasia

Arun Pradhan, Lixiao Che, Vladimir Ustiyan, Abid A. Reza, Nicole M. Pek, Yufang Zhang, Andrea B. Alber, Timothy R. Kalin, Jennifer A. Wambach, Mingxia Gu, Darrell N. Kotton, Matthew E. Siefert, Assem G. Ziady, Tanya V. Kalin, Vladimir V. KalinichenkoBoston University and Boston Medical Center. University of Cincinnati. Washington University in St. Louis School of

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Regulatory B cells protect against chronic hypoxia-induced pulmonary hypertension by modulating the Tfh/Tfr immune balance

Cheng Li, Pingping Liu, Huiling Yao, Hao Zhu, Shaoze Zhang, Famg Meng, San Li, Guang Li, Yanping Peng, Jing Gu, Liming Zhu, Yongliang Jiang, Aiguo DaiHunan Provincial People’s Hospital and The First Affiliated Hospital of Hunan Normal University. Hunan Children’s Hospital. Hunan University of Chinese Medicine. Hunan Province Key Laboratory of Vascular Biology and Translational

Regulatory B cells protect against chronic hypoxia-induced pulmonary hypertension by modulating the Tfh/Tfr immune balance Read More »

Computed tomographic parenchymal lung findings in premature infants with pulmonary vein stenosis

Barry O’Callaghan, Jenny E. Zablah, Jason P. Weinman, Erin K. Englund, Gareth J. Morgan, D. Dunbar Ivy, Benjamin S. Frank, David Andrew Mong, LaDonna J. Malone, Lorna P. BrowneChildren’s Hospital Colorado, Aurora and University of Colorado Medical SchoolUnited States Pediatric RadiologyPediatr Radiol 2023; DOI: 10.1007/s00247-023-05673-y AbstractBackground: Developmental pulmonary vein pulmonary vein stenosis in the setting of prematurity

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