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Identification of the Key Pathways and Genes in Hypoxia Pulmonary Arterial Hypertension Following Intrauterine Growth Retardation

Weifen Zhu, Ziming Zhang, Weiwei Gui, Zheng Shen, Yixin Chen, Xueyao Yin, Li Liang, Lin LiThe Affiliated Sir Run Run Shaw Hospital, Children’s Hospital and The First Affiliated Hospital of Zhejiang University.China Frontiers in Molecular BiosciencesFront Mol Biosci 2022; DOI: 10.3389/fmolb.2022.789736 AbstractHigh-throughput sequencing and weighted gene co-expression network analysis (WGCNA) were used to identify susceptibility modules […]

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Long-term outcomes of living-donor lobar lung transplantation

Seiichiro Sugimoto, Hiroshi Date, Kentaroh Miyoshi, Shinji Otani, Megumi Ishihara, Masaomi Yamane, Shinichi ToyookaOkayama University Hospital. Kyoto University Graduate School of Medicine.Japan Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2022; 164: 440-448DOI: 10.1016/j.jtcvs.2021.08.090 AbstractObjective: Although living-donor lobar lung transplantation (LDLLT) enables an intermediate survival similar to cadaveric lung transplantation, the long-term outcome remains unknown. We

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Home High-Flow Nasal Cannula Therapy in Children with Congenital Heart Disease

Yuka Hanaki, Jun Muneuchi, Junko Yamamoto, Chie Yokota, Junya Ohmura, Hiroki Ezaki, Miwa Yoshino, Ryoko Nakamura, Miho Takeichi, Yuichiro Sugitani, Ryouhei Matsuoka, Hirohito Doi, Mamie Watanabe, Yasukiko TakahashiKyushu Hospital and Japan Community Healthcare Organization. Japan Pediatric CardiologyPediatr Cardiol 2022; 43: 1131-1135DOI: 10.1007/s00246-022-02834-y AbstractHigh-flow nasal cannula (HFNC) therapy has been applied in the perioperative respiratory care for

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Bleeding Complications in Neonates Receiving Extracorporeal Membrane Oxygenation and Controlled Hypothermia

Swosti Joshi, Vilmaris Quinones Cardona, Erica Poletto, Ogechukwu MenkitiDrexel University College of Medicine Philadelphia. Saint Christopher’s Hospital for Children.United States American Journal of PerinatologyAm J Perinatol 2022; DOI: 10.1055/a-1786-8688 AbstractObjective: Safety and efficacy data on controlled hypothermia (CH) for neonates with moderate to severe hypoxic ischemic encephalopathy has been extrapolated to a subgroup of these patients who

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Cardiorespiratory adaptation to low-dose dexamethasone for lung disease in extremely preterm infants: A prospective echocardiographic study

Arvind Sehgal, Marcel F. Nold, Calum T. Roberts, Samuel MenahemMonash Children’s Hospital, Monash Medical Centre and Monash University. Hudson Institute of Medical Research.Australia Journal of PhysiologyJ Physiol 2022; 600: 4361-4373DOI: 10.1113/JP282973 AbstractThe cardiovascular impact of dexamethasone (Dex) is not well understood. Most data are obtained from a 6 week, high-dose regimen, and are limited to findings

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Identification of SOX2 Interacting Proteins in the Developing Mouse Lung With Potential Implications for Congenital Diaphragmatic Hernia

Kim A. A. Schilders, Gabriëla G. Edel, Evelien Eenjes, Bianca Oresta, Judith Birkhoff, Anne Boerema-de Munck, Marjon Buscop-van Kempen, Panagiotis Liakopoulos, Petros Kolovos, Jeroen A. A. Demmers, Raymond Poot, Rene M. H. Wijnen, Dick Tibboel and Robbert J. RottierErasmus Medical Center and Sophia Children’s Hospital. Democritus University of Thrace. Netherlands and Greece Frontiers in PediatricsFront

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Pulmonary vasodilator therapies in pulmonary arterial hypertension associated with CHD: a systematic review and network meta-analysis

Jun Yasuhara, Kae Watanabe, Atsuyuki Watanabe, Takuro Shirasu, Yuichi Matsuzaki, Hirofumi Watanabe, Hisato Takagi, Naokata Sumitomo, Toshiki KunoNationwide Children’s Hospital. Ann & Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg School of Medicine. University of Tsukuba Hospital. University of Virginia. McGill University. Medical University of South Carolina. Shizuoka Medical Center. Saitama Medical

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Implementation of an Inhaled Nitric Oxide Weaning Protocol and Stewardship in a Level 4 NICU to Decrease Inappropriate Use

Walid A. Hussain, Deborah S. Bondi, Pooja Shah, Sherwin E. Morgan, Sudhir Sriram, Michael D. SchreiberLoyola University Medical Center. University of Chicago Medicine Comer Children’s Hospital. United States Journal of Pediatric Pharmacology and TherapeuticsJ Pediatr Pharmacol Ther 2022; 27: 284-291DOI: 10.5863/1551-6776-27.3.284 AbstractObjective: Inhaled nitric oxide (iNO) is an effective but expensive treatment of pulmonary hypertension in newborns,

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Expanding ACTA2 genotypes with corresponding phenotypes overlapping with smooth muscle dysfunction syndrome

Anita Kaw, Kaveeta Kaw, Ellen M. Hostetler, Ana Beleza-Meireles, Adam Smith-Collins, Catherine Armstrong, Ingrid Scurr, Timothy Cotts, Rajani Aatre, Michael J. Bamshad, Dawn Earl, Abraham Groner, Katherine Agre, Yehuda Raveh, Callie S. Kwartler, Dianna M. MilewiczMcGovern Medical School, University of Texas Health Science Center at Houston. St Michael’s Hospital. Bristol Royal Hospital for Children. University

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Vitamin D Levels and Cardiopulmonary Status in Infants with Acute Bronchiolitis

Ana Estalella-Mendoza, Ana Castellano-Martinez, Jose Carlos Flores-Gonzalez, Lorena Estepapedregosa, Patricia Rodriguez-Campoy, Moises Rodriguez-GonzalezPuerta del Mar University Hospital. Spain Indian PediatricsIndian Pediatr 2022; 59: 384-387DOI: Not Available AbstractBackground: To assess association of Vitamin D deficiency with cardiac and pulmonary status in infants with acute bronchiolitis.Methods: Infants hospitalized with acute bronchiolitis were enrolled and classified as those with serum

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