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Hospital outcomes in pediatric patients with Prader-Willi syndrome (PWS) undergoing orthopedic surgery: A 12-year analysis of national trends in surgical management and inpatient hospital outcomes

Kade S. McQuivey, Andrew S. Chung, Michael R. Jones, Justin L. Makovicka, Zachary K. Christopher, Joseph C. Brinkman, Mohan BelthurMayo Clinic Arizona. Midwestern University College of Osteopathic Medicine. Phoenix Children Hospital.United States Journal of Orthopaedic ScienceJ Orthop Sci 2022; 27: 1304-1308DOI: 10.1016/j.jos.2021.08.005 AbstractBackground: The incidence of orthopedic disorders amongst patients with Prader-Willi Syndrome (PWS) is high when […]

Hospital outcomes in pediatric patients with Prader-Willi syndrome (PWS) undergoing orthopedic surgery: A 12-year analysis of national trends in surgical management and inpatient hospital outcomes Read More »

A multicentric evaluation of pediatric lung transplantation in Italy

Marco Schiavon, Stafania Camgni, Federico Venuta, Lorenzo Rosso, Massimo Boffini, Francesco Parisi, Alessandro Bertani, Federica Meloni, Piero Paladini, Eleonora Faccioli, Michele Colledan, Daniele Diso, Margherita Cattaneo, Fabrizio Scalini, Sara Alfieri, Domenica Giunta, Monica Morosini, Luca Luzzi, Giulia Lorenzoni, Andrea Dell’Amore, Federico ReaUniversity Hospital of Padova. ASST Giovanni XXIII. University of Rome. University of Milan. University

A multicentric evaluation of pediatric lung transplantation in Italy Read More »

Hypoxic preconditioning improves the survival and pro-angiogenic capacity of transplanted human umbilical cord mesenchymal stem cells via HIF-1α signaling in a rat model of bronchopulmonary dysplasia

Chang Hao, Jingyi You, Huijun Qiu, Ou Zhou, Jiang Liu, Wenjing Zou, Ke Yeng, Zhou Fu, Lin ZouChildren’s Hospital of Chongqing Medical University. China Biochemical and Biophysical Research CommunicationsBiochem Biophys Res Commun 2022; 605: 111-118DOI: 10.1016/j.bbrc.2022.03.044 AbstractBronchopulmonary dysplasia (BPD) is a serious chronic respiratory disease that predominates in the neonatal period. Currently, efficacious and effective specific

Hypoxic preconditioning improves the survival and pro-angiogenic capacity of transplanted human umbilical cord mesenchymal stem cells via HIF-1α signaling in a rat model of bronchopulmonary dysplasia Read More »

Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant

Motaharehsadat Heydarian, Prajakta Oak, Xin Zhang, Nona Kamgari, Alida Kindt, Markus Koschlig, Tina Pritzke, Erika Gonzalez- Rodriguez, Kai Förster, Rory E Morty, Friederike Häfner, Christoph Hübener, Andreas W Flemmer, Ali Oender Yildirim, Deepti Sudheendra, Xuefei Tian, Agnese Petrera, Holger Kirsten, Peter Ahnert, Nick Morrell, Tushar J Desai, Jennifer Sucre, Edda Spiekerkoetter, Anne HilgendorffHelmholtz Zentrum München.

Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant Read More »

The long-term outcome following thoraco-amniotic shunting for congenital lung malformations

Ancuta Muntean, Ramona Cazacu, Niyi Ade-Ajayi, Shailesh B Patel, Kypros Nicolaides, Mark DavenportKings College Hospital. United Kingdom Journal of Pediatric SurgeryJ Pediatr Surg 2023; 58: 213-217DOI: 10.1016/j.jpedsurg.2022.10.028 AbstractAim of the study: Insertion of a thoraco amniotic shunt (TAS) during fetal life is a therapeutic option where there is a high risk of death secondary to large congenital

The long-term outcome following thoraco-amniotic shunting for congenital lung malformations Read More »

Vascular Reactions of the Diving Reflex in Men and Women Carrying Different ADRA1A Genotypes

Tatyana Baranova, Ekaterina Podyacheva, Tatyana Zemlyanukhina, Dmitrii Berlov, Maria Danilova, Oleg Glotov, Andrey GlotovSaint Petersburg State University. D.O. Ott’s Institute of Obstetrics. Pediatric Research and Clinical Center for Infectious Diseases.Russia International Journal of Molecular SciencesInt J Mol Sci 2022; 23: DOI: 10.3390/ijms23169433 AbstractThe diving reflex is an oxygen-saving mechanism which is accompanied by apnea, reflex bradycardia

Vascular Reactions of the Diving Reflex in Men and Women Carrying Different ADRA1A Genotypes Read More »

Notch signalling in healthy and diseased vasculature

Francesca Del Gaudio, Dongli Liu, Urban LendahlKarolinska Institutet. The First Affiliated Hospital of Guangxi Medical University.Sweden and China Open BiologyOpen Biol 2022; 12: DOI: 10.1098/rsob.220004 AbstractNotch signalling is an evolutionarily highly conserved signalling mechanism governing differentiation and regulating homeostasis in many tissues. In this review, we discuss recent advances in our understanding of the roles that

Notch signalling in healthy and diseased vasculature Read More »

Hippo signaling pathway and respiratory diseases

Weifeng Tang, Min Li, Xiaoting Yangzhong, Xifeng Zhang, Anju Zu, Yunjiao Hou, Lin Li, Shibo SunFirst Affiliated Hospital and Kunming Medical University. China Cell Death DiscoveryCell Death Discov 2022; 8: DOI: 10.1038/s41420-022-01020-6 AbstractThe hippo signaling pathway is a highly conserved evolutionary signaling pathway that plays an important role in regulating cell proliferation, organ size, tissue development,

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Physiologically based pharmacokinetic modelling of treprostinil after intravenous injection and extended-release oral tablet administration in healthy volunteers: An extrapolation to other patient populations including patients with hepatic impairment

Xuemei Wu, Xiaohan Zhang, Ruichao Xu, Imam Hussain Shaik, Raman VenkataramananUniversity of Pittsburgh School of Pharmacy. Fujian Medical University Union Hospital. University of Virginia. University of Pittsburgh School of Medicine.United States and China British Journal of Clinical PharmacologyBrit J Clin Pharmacol 2022; 88: 587-599DOI: 10.1111/bcp.14966 AbstractAims: Pulmonary arterial hypertension (PAH) is characterized by increased pulmonary arterial pressure,

Physiologically based pharmacokinetic modelling of treprostinil after intravenous injection and extended-release oral tablet administration in healthy volunteers: An extrapolation to other patient populations including patients with hepatic impairment Read More »

Risk factors that affect the degree of bronchopulmonary dysplasia in very preterm infants: a 5-year retrospective study

Tingting Yang, Qianqian Shen, Siyu Wang, Tianfang Dong, Liang Liang, Fan Xu, Youfang He, Chunlei Li, Fang Luo, Jiahong Liang, Chunhui Tang, Jinghui YangKunming University of Science and Technology. The First People’s Hospital of Yunnan Province. Dali University. The First Hospital of Kunming. Yunnan University of Traditional Chinese Medicine. The Affiliated Hospital of Kunming University

Risk factors that affect the degree of bronchopulmonary dysplasia in very preterm infants: a 5-year retrospective study Read More »

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