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Neonatal Outcomes of Term Infants Born with Meconium-Stained Amniotic Fluid

Carlo Dani, Martina Ciarcià1, Vittoria Barone, Mariarosaria Di Tommaso, Federico Mecacci, Lucia Pasquini, Simone PratesiCareggi University Hospital, Largo Brambilla. University of Florence. Italy ChildrenChildren 2023; 10 DOI: 10.3390/children10050780 AbstractBackground Meconium-stained amniotic fluid (MSAF) is considered an alarming sign of possible fetal compromise and it has recently been reported that neonatal outcome correlates with the degree of meconium

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Pediatric pulmonary arterial hypertension due to a novel homozygous GDF2 missense variant affecting BMP9 processing and activity

L. Chomette, E. Hupkens, M. Romitti, L. Dewachter, J. L.Vachiéry, S. Bailly, S. Costagliola, G. Smits, E. Tillet, Antoine BondueHôpital Erasme, Hôpital Universitaire de Bruxelles and Université Libre de Bruxelles. Laboratory BioSanté and Université Grenoble Alpes.Belgium and France American Journal of Medical GeneticsAm J Med Genet 2023; 191(8):2064-2073DOI: 10.1002/ajmg.a.63236 AbstractPulmonary arterial hypertension (PAH) is a rare

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Evaluation of preterm infants having bronchopulmonary dysplasia with echocardiography and serum biomarkers

O. Pamukcu, N. Narin, S. Sunkak, A. TuncayErciyes University School of Medicıne.Turkey Cardiology in the YoungCardiol Young 2023; DOI: 10.1017/S1047951123001361 AbstractBackground and objectives: Pulmonary hypertension is frequent in infants with bronchopulmonary dysplasia. Echocardiography is easy to perform, non-invasive, and recommended by guidelines even though solely it is not enough. Catheterisation is gold standard but invasive, expensive, and

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Severe Pulmonary Arterial Hypertension in Healthy Young Infants: Single Center Experience

Shrikiran Aroor, Koushik Handattu, Suneel C. Mundkur, Aditya Verma, Praveen C. Samuel, Akkatai S. Teli, Gujan BangaKasturba Medical College. India Indian PediatricsIndian Pediatr 2023; AbstractObjectives: We studied the clinical presentation and management of acute pulmonary arterial hypertension (PAH) in healthy young infants, and the effect thiamine therapy.Methods: Review of hospital records was conducted for 56 healthy infants

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Macitentan in the Young-Mid-term Outcomes of Patients with Pulmonary Hypertensive Vascular Disease treated in a Pediatric Tertiary Care Center

Sulaima Albinni, Julian Heno, Imre Pavo, Erwin Kitzmueller, Manfred Marx, Ina Michel‑BehnkeMedical University of Vienna.Austria Paediatric DrugsPaediatr Drugs 2023; 25: 467-481DOI: 10.1007/s40272-023-00573-y AbstractBackground: Pulmonary hypertension (PH) is a severe hemodynamic condition with high morbidity and mortality. Approved targeted therapies are limited for pediatric subjects, and treatments are widely adopted from adult algorithms. Macitentan is a safe and effective drug used for adult PH,

Macitentan in the Young-Mid-term Outcomes of Patients with Pulmonary Hypertensive Vascular Disease treated in a Pediatric Tertiary Care Center Read More »

Novel scoring tool of hypoxemic respiratory failure and pulmonary hypertension for defining severity of persistent pulmonary hypertension of newborn

Sage Timberline, Avni Bhatt, Sherzana Sunderji, Daniel J. Tancredi, Satyan Lakshminrusimha, Heather SiefkesUniversity of Virginia. University of California, Davis. United States Journal of PerinatologyJ Perinatol 2023; DOI: 10.1038/s41372-023-01762-w AbstractObjective: To obtain preliminary validity data for a hypoxemic respiratory failure/pulmonary hypertension (HRF/PH) score for classifying persistent pulmonary hypertension of the newborn (PPHN).Study design: Retrospective chart review of 100 consecutive

Novel scoring tool of hypoxemic respiratory failure and pulmonary hypertension for defining severity of persistent pulmonary hypertension of newborn Read More »

Efficacy of Sildenafil in Infants with Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension

Kacie Dillon, Vineet Lamba, Ranjit R. Philip, Mark F. Weems, Ajay J. Talati University of Tennessee Health Science Center.United States ChildrenChildren 2023; DOI: 10.3390/children10081397 AbstractBackground: Pulmonary hypertension (PH) is a common comorbidity in infants with bronchopulmonary dysplasia (BPD). Sildenafil is a widely recognized therapy for PH, but its efficacy in infants with BPD is questionable. We propose

Efficacy of Sildenafil in Infants with Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension Read More »

Outcomes of pregnancy in mice with pulmonary hypertension induced by Hypoxia/SU5416

Yang Liu, Jing Deng, Yichen Zhao, Kemin Liu, Wenbo Zhang, Qiang Wang, Jiangang Wang, Chunmei PiaoBeijing Anzhen Hospital Affiliated to Capital Medical University. Yanbian University. Beijing Institute of Heart Lung and Blood Vessel Diseases. China Biochemical and Biophysical Research CommunicationsBiochem Biophys Res Commun 2023; 669: 128-133DOI: 10.1016/j.bbrc.2023.05.051 AbstractBackground: Pulmonary hypertension (PH) seriously affects the health of patients.

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Infantile hemangiomatosis, a rare cause of high-output heart failure and pulmonary hypertension in the newborn baby: a case report

Nurdan Erol, Abdullah Alpinar, Nihan Uygur KulcuHealth Sciences University Zeynep Kamil Women and Children Diseases Training and Research Hospital.Turkey Cardiology in the YoungCardiol Young 2023; DOI: 10.1017/S1047951123001488 AbstractInfantile hemangiomatosis is among the most common vascular tumours of childhood that is generally accepted as benign. Some cases may have multiple hemangiomas with organ involvement, especially of the

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Intrapulmonary arterial contraction assay reveals region-specific deregulation of vasoreactivity to lung injuries

Yan Bai, Guang Li, Laiming Yung, Paul B. Yu, Xingbin AiMassachusetts General Hospital and Harvard Medical School. Brigham and Women’s Hospital. Renmin Hospital and Wuhan University. United States and China American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2023; 325: L114-L124DOI: 10.1152/ajplung.00293.2022 AbstractIntrapulmonary arteries located in the proximal lung

Intrapulmonary arterial contraction assay reveals region-specific deregulation of vasoreactivity to lung injuries Read More »

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