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Elastin stabilization prevents impaired biomechanics in human pulmonary arteries and pulmonary hypertension in rats with left heart disease

Mariya M. Kucherenko, Pengchao Sang, Juquan Yao, Tara Gransar, Saphala Dhital, Jana Grune, Szandor Simmons, Laura Michalick, Dag Wulsten, Mario Thiele, Orr Shomroni, Felix Hennig, Ruhi Yeter, Natalia Solowjowa, Gabriela Salinas, Georg N. Duda, Volkmar Falk, Naren R. Vyavahare, Wolfgang M. Kuebler, Christoph KnosallaDeutsches Herzzentrum der Charité. Charité-Universitätsmedizin Berlin. Freie Universität Berlin and Humboldt-Universität zu […]

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Pathogenesis, clinical features, and phenotypes of pulmonary hypertension associated with interstitial lung disease: A consensus statement from the Pulmonary Vascular Research Institute’s Innovative Drug Development Initiative – Group 3 Pulmonary Hypertension

Lucilla Piccari, Brian Allwood, Katerina Antoniou, Jonathan H. Chung, Paul M. Hassoun, Sylvia M. Nikkho, Rajan Saggar, Oksana A. Shlobin, Patrizio Vitulo, Steven D. Nathan, Stephen John WortHospital del Mar. Stellenbosch University and Tygerberg Hospital. University of Crete School of Medicine. The University of Chicago. Johns Hopkins University. Bayer AG. University of California Los Angeles

Pathogenesis, clinical features, and phenotypes of pulmonary hypertension associated with interstitial lung disease: A consensus statement from the Pulmonary Vascular Research Institute’s Innovative Drug Development Initiative – Group 3 Pulmonary Hypertension Read More »

Inhaled nitric oxide use in newborns

Souvik Mitra, Gabriel AltitCanadian Paediatric Society.Canada Paediatrics and Child HealthPaediatr Child Health 2023; 28: 119-127DOI: 10.1093/pch/pxac107 AbstractInhaled nitric oxide (iNO), a selective pulmonary vasodilator, is used as a therapeutic modality in infants with hypoxemic respiratory failure (HRF) associated with persistent pulmonary hypertension of the newborn (PPHN). iNO should ideally be initiated following echocardiographic confirmation of PPHN.

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Management of pulmonary arterial hypertension during pregnancy

Kaushiga Krishnathasan, Andrew Constantine, Isma Rafiq, Ana Barradas Pires, Hannah Douglas, Laura C. Price, Konstantinos DimopoulosRoyal Brompton Hospital and Royal Brompton & Harefield Hospitals. Imperial College. St Thomas’ Hospital. King’s College.United Kingdom Expert Review of Respiratory MedicineExpert Rev Respir Med 2023; 17: 413-423DOI: 10.1080/17476348.2023.2210838 AbstractIntroduction: Pulmonary arterial hypertension (PAH) is defined as a mean pulmonary artery pressure

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Impact of the COVID-19 pandemic on chronic disease management and patient reported outcomes in patients with pulmonary hypertension: The Pulmonary Hypertension Association Registry

Megan Mayer, David B. Badesch, Kelly H. Nielsen, Steven Kawut, Todd Bull, John J. Ryan, Jeffrey Sager, Sula Mazimba, Anna Hemnes, James Klinger, James Runo, John W. McConnell, Teresa DeMarco, Murali M. Chakinala, Delphine Yung, Jean Elwing, Adolfo Kaplan, Rahul Argula, Raymond Pomponio, Ryan Peterson, Peter HountrasUniversity of Colorado. University of Pennsylvania. University of Utah.

Impact of the COVID-19 pandemic on chronic disease management and patient reported outcomes in patients with pulmonary hypertension: The Pulmonary Hypertension Association Registry Read More »

Pulmonary Hypertension in Chronic Lung Diseases: What Role Do Radiologists Play?

Adele Valentini, Paola Franchi, Giuseppe Cicchetti, Gaia Messana, Greta Chiffi, CeciliaStrappa, Lucio Calandriello, Annemiliadel Ciello, Alessandra Farchione, Lorenzo Preda, Anna Rita LariciFondazione IRCCS Policlinico San Matteo. G. Mazzini Hospital. Fondazione Policlinico Universitario. University of Pavia. Università Cattolica del Sacro Cuore. Italy DiagnosticsDiagnostics 2023; 13: DOI: 10.3390/diagnostics13091607 AbstractPulmonary hypertension (PH) is a pathophysiological disorder, defined by a

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Prenatal MRI assessment of mediastinal shift angle as a feasible and effective risk stratification tool in isolated right-sided congenital diaphragmatic hernia

Wen Ding, Yuanyuan Gu, Kaiyu Wang, Huiying Wu, Xiachun Zhang, Rui Zhang, Hongying Wang, Li Huang, Junjian Lv, Bo Xia, Wei Zhong, Qiuming He, Longlong HouGuangzhou Women and Children’s Medical Center and Guangzhou Medical University. China European RadiologyEur Radiol 2023; DOI: 10.1007/s00330-023-10178-1 AbstractObjectives: To develop a mediastinal shift angle (MSA) measurement method applicable to right-sided congenital diaphragmatic

Prenatal MRI assessment of mediastinal shift angle as a feasible and effective risk stratification tool in isolated right-sided congenital diaphragmatic hernia Read More »

NT-proBNP Is a Predictor of Mortality in Adults with Pulmonary Arterial Hypertension Associated with Congenital Heart Disease

Susanne J. Maurer, Veronika Habdank, Jürgen Hörer, Peter Ewert, Oktay TutarelGerman Heart Centre Munich and Technical University of Munich. Ludwig-Maximilians Universität.Germany Journal of Clinical MedicineJ Clin Med 2023; 12DOI: 10.3390/jcm12093101 AbstractBackground: About 5-10% of adults with congenital heart disease (ACHD) will develop pulmonary arterial hypertension (PAH), which is associated with significant mortality. Studies on risk factors for

NT-proBNP Is a Predictor of Mortality in Adults with Pulmonary Arterial Hypertension Associated with Congenital Heart Disease Read More »

Short-time mortality and severe complications of very premature infants-a multicenter retrospective cohort study from Jiangsu Province during 2019-2021

Ya Pan, Huaiyan Wang, Yan Xu, Xiaohua Zhang, Xiaoqing Chen, Xueting Liu, Songlin Liu, Yan Gao, Weiwei Hou, Zhaojun Pan, Xinping Wu, Mei Xue, Mingfu Wu, Huimin Ju, Weimin Wu, Shuping HanWomen’s Hospital of Nanjing Medical University and Nanjing Maternity and Child Health Care Hospital. Changzhou Maternity and Child Health Care Hospital. Affiliated Hospital of

Short-time mortality and severe complications of very premature infants-a multicenter retrospective cohort study from Jiangsu Province during 2019-2021 Read More »

Cardiac Magnetic Resonance Derived Left Ventricular Eccentricity Index and Right Ventricular Mass Measurements Predict Outcome in Children with Pulmonary Arterial Hypertension

Meindina G. Haarman, Iris Coenraad, Quint A. J. Hagdorn, Hans L. Hillege, Tineke P. Willems, Rolf M. F. Berger, Johannes M. DouwesBeatrix Children’s Hospital and University Medical Center Groningen. Netherlands ChildrenChildren 2023; 10DOI: 10.3390/children10040756 AbstractPulmonary arterial hypertension (PAH) is associated with increased right ventricular (RV) afterload, affecting RV remodeling and RV performance, a major determinant of

Cardiac Magnetic Resonance Derived Left Ventricular Eccentricity Index and Right Ventricular Mass Measurements Predict Outcome in Children with Pulmonary Arterial Hypertension Read More »

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