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Clinical impact of subcutaneous treprostinil in trisomy 21 patient with pulmonary arterial hypertension associated with CHD

Ryusuke Numata, Kiyohiro Takigiku, Kouta TakeiNagano Children’s HospitalJapan Cardiology in the YoungCardiol Young 2022; DOI: 10.1017/S1047951121005096 AbstractSubcutaneous treprostinil is commonly used to improve idiopathic pulmonary arterial hypertension in children. However, its effectiveness has not been reported in trisomy 21. We report the case of 9-year-old boy in trisomy 21 with CHD-pulmonary artery hypertension after surgical correction […]

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A Study on the Molecular Mechanism of High Altitude Heart Disease in Children

Qu-Zhen Tashi, Sang-Bu Tsering, Na-Ni Zhou, Yi Zhang, Yu-Juan Huang, Jia Jia, Ting-Jun LiShigatse Peopel’s Hospital. Fujungenetics Technologies Inc. Children’s Hospital of Shanghai.China Pharmacogenomics and Personalized MedicinePharmgenomica Pers Med 2022; 15: 721-731DOI: 10.2147/PGPM.S356206 AbstractObjective: High altitude heart disease (HAHD) is a common pediatric disease in high altitude areas. It usually occurs in people who have lived for

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Seven-day in vivo testing of a novel, low-resistance, pumpless pediatric artificial lung for long-term support

Brian P. Fallon, Alex J. Thompson, Aaron R. Prater, Skylar Buchan, Trevor Alberts, Mark Hoenerhoff, Alvaro Rojas-Pena, Robert H. Bartlett, Ronald B. HirschlUniversity of Michigan Medical School and Michigan Medicine.United States Journal of Pediatric SurgeryJ Pediatr Surg 2022; 57: 614-623DOI: 10.1016/j.jpedsurg.2022.07.006 AbstractIntroduction: For children with end-stage lung disease that cannot wean from extracorporeal life support (ECLS), a

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Quantitative cardiopulmonary magnetic resonance imaging in neonatal congenital diaphragmatic hernia

Jean A. Tkach, Nara S. Higano, Michael D. Taylor, Ryan A. Moore, Monir Hossain, Guixia Huang, David R. Spielberg, Sean B. Fain, Paul S. Kingma, Jason C. WoodsCincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine. Texas Children’s Hospital. University of Iowa. University of Wisconsin.United States Pediatric RadiologyPediatr Radiol 2022; 52: 2306-2318DOI: 10.1007/s00247-022-05384-w

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Eisenmenger Syndrome Among Children with Unrepaired Congenital Heart Defects in Yunnan, China

Fangqi Guo, Ruey-Kang Chang, Robert C. DetranoUniversity of California Irvine. Harbor-UCLA Medical Center. China California Heart Watch.United States and China Pediatric CardiologyPediatr Cardiol 2022; 43: 1848-1856DOI: 10.1007/s00246-022-02922-z AbstractEisenmenger syndrome is a life-threatening complication of congenital heart defects (CHD). Since Eisenmenger syndrome among children of repaired CHD is rare, very few studies have had the necessary data

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COL18A1 genotypic associations with endostatin levels and clinical features in pulmonary arterial hypertension: a quantitative trait association study

Catherine E. Simpson, Megan Griffiths, Jun Yang, Melanie K. Nies, Dhananjay Vaidya, Stephanie Brandal, Lisa J. Martin, Michael W. Pauciulo, Katie A. Lutz, Anna W. Coleman, Eric D. Austin, D. Dunbar Ivy, William C. Nichols, Allen D. Everett, Paul M. Hassoun, Rachel L. DamicoJohns Hopkins University. Cincinnati Children’s Hospital Medical Center and University of Cincinnati

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Non-criteria antiphospholipid antibodies and pediatric rheumatic disease: a case series

Shawn A. Mahmud, Danielle R. Bullock, Colleen K. Correll, Patricia M. Hobday, Mona M. Riskalla, Richard K. Vehe, Bryce A. BinstadtUniversity of Minnesota. United States Pediatric RheumatologyPediatr Rheumatol 2022; 20: DOI: 10.1186/s12969-022-00732-4 AbstractBackground: Non-criteria antiphospholipid antibodies (NC-aPL) are a relatively undefined subgroup of antiphospholipid antibodies (aPL). Knowledge about NC-aPL in adults is limited and even less is

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Primary graft dysfunction grade 3 following pediatric lung transplantation is associated with chronic lung allograft dysfunction

Wai Wong, Brandy Johnson, Pi Chun Cheng, Maureen B. Josephson, Katsuhide Maeda, Robert A. Berg. Steven M. Kawut, Michael O. Harhay, Samuel B. Goldfarb, Nadir Yehya, Adam S. HimebauchHarvard Medical School and Boston Children’s Hospital, Boston. Perelman School of Medicine at the University of Pennsylvania and Children’s Hospital of Philadelphia. Indiana University School of Medicine

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Doppler Echocardiographic Features of Pulmonary Vein Stenosis in Ex-Preterm Children

Yalin Lin, Alena K. Amin, Roberta L. Keller, David F. Teitel, Hythem M. NawaytouUniversity of California, San Francisco.United States Journal of the American Society of EchocardiographyJ Am Soc Echocardiogr 2022; 35: 435-442DOI: 10.1016/j.echo.2021.12.015 AbstractBackground: Echocardiography is used to screen for the presence of pulmonary vein stenosis (PVS) in ex-preterm infants and children. However, there are no standard

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Predicting the Severity and Outcome of Persistent Pulmonary Hypertension of the Newborn Using New Echocardiography Parameters

Muhammad Umer Butt, Ahmad Jabri, Hani Hamade, Ahmad Al Abdouh, Mohammed Mhanna, Faris Haddadin, Farhan Nasser, Nour Hammad, Deaa Abu Jazar, Ahmad J. Toumar, Aisha Siraj, Kathir Balakumaran, Michel IlbawiMetrohealth Medical Center. St. Agnes Hospital. University of Toledo. Baylor College of Medicine. University Hospitals Cleveland Medical Centers. University of Texas Medical Branch. Kent Hospital. Advocate Children’s

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