All Categories Archives - Page 18 of 290

H2S Donor Therapy Reverses Established Pulmonary Arterial Hypertension and Pulmonary Vascular Structural Remodeling in Rats

Jie Zheng, Yanan Zhang, Boyang Lv, Yuanyuan Ma, Xuecong Zhong, Junbao Du, Hongfang Jin, Yaqian HuangPeking University First Hospital and Peking University.China BiomedicinesBiomedicines 2026;DOI: 10.3390/biomedicines14040760 AbstractObjectives: Downregulation of the endogenous gasotransmitter hydrogen sulfide (H2S) contributes to the pathogenesis of pulmonary arterial hypertension (PAH). While prophylactic H2S supplementation prevents PAH initiation in different rat models, its ability […]

H2S Donor Therapy Reverses Established Pulmonary Arterial Hypertension and Pulmonary Vascular Structural Remodeling in Rats Read More »

Extracorporeal membrane oxygenation as a bridge to cardiac catheterization in a pediatric patient with pulmonary arteriovenous malformation: A case report and literature review

Mohammed Alzaid, Nada Aljassim, Turki Alshahrani, Abubaker Alkalifa, Anfal Alsalhi, Mohammed AlGhoshimi, Omar AltamimiChildren’s Specialized Hospital, King Fahad Medical City. Saudi Arabia Respiratory Medicine Case ReportsRespir Med Case Rep 2026; DOI: 10.1016/j.rmcr.2026.102417 AbstractIntroduction: Pulmonary arteriovenous malformations (PAVMs) are rare vascular anomalies that can present with profound hypoxemia in children. While transcatheter embolization is the treatment of choice,

Extracorporeal membrane oxygenation as a bridge to cardiac catheterization in a pediatric patient with pulmonary arteriovenous malformation: A case report and literature review Read More »

Efficacy and safety of fenfluramine in Dravet syndrome; A monocentric, observational study focused on initial dose, blood concentration, and reduction of concomitant medications

Akihiro Iguchi, Tokito Yamaguchi, Yu Tsuyusaki, Hideyuki Otani, Satoshi Mizutani, Mitsuhiro Miyashita, Manami Yabe, Katsumi ImaiNHO Shizuoka Institute of Epilepsy and Neurological Disorders and Asahi General Hospital. Japan Epilepsy and BehaviorEpilepsy Behav 2026; DOI: 10.1016/j.yebeh.2026.111070 AbstractObjective: To evaluate the optimal initial dose, efficacy, and adverse events of fenfluramine (FFA) in the treatment of intractable epilepsy in Dravet

Efficacy and safety of fenfluramine in Dravet syndrome; A monocentric, observational study focused on initial dose, blood concentration, and reduction of concomitant medications Read More »

A child with cobalamin C deficiency caused by complex heterozygous variation of c.567dupT and c.80A > G complicated with pulmonary arterial hypertension and hydrocephalus: A case report and literature review

Cui, Xuxia, Zhong, Yajing, Yin, ChongjuanFirst Hospital of Shanxi Medical University.China MedicineMedicine 2026; 105: DOI: 10.1097/MD.0000000000048340 AbstractRationale: Cobalamin C (cblC) deficiency is one of the most common congenital vitamin B12 metabolic abnormalities, and may cause severe neurologic symptoms, gastrointestinal and nephritic symptoms.Patient concerns: A 9-month-old boy presented with a 10-day history of progressive dyspnea and weak cough, accompanied by

A child with cobalamin C deficiency caused by complex heterozygous variation of c.567dupT and c.80A > G complicated with pulmonary arterial hypertension and hydrocephalus: A case report and literature review Read More »

Parental knowledge and awareness of complications of recurrent adenotonsillitis and its surgical management in children in the Jazan region, Saudi Arabia: a cross-sectional study

Abdulelah A. Otaif, Ramzi M. Dighriri, Abdulrahman A. Otaif, Riyadh A. Jahlan, Osama A. Alotayf, Ali Y. Shaikh, Saud N. Alwadani, Raghad M. Alnami, Asma M. SoweediJazan University, Jazan. Armed Forces Hospital.Saudi Arabia Frontiers in PediatricsFront Pediatr 2026; DOI: 10.3389/fped.2026.1761634 AbstractBackground: Recurrent adenotonsillitis is a frequent pediatric condition with complications affecting sleep, growth, hearing, and behavior. Parental

Parental knowledge and awareness of complications of recurrent adenotonsillitis and its surgical management in children in the Jazan region, Saudi Arabia: a cross-sectional study Read More »

Bronchopulmonary Dysplasia: A Contemporary Review for Pediatric Practice

Marie Berg, Silvia Maria del Rocio Delgado-Villalta, Catalina BazacliuUniversity of Florida College of Medicine. United States Pediatrics in ReviewPediatr in Rev 2026; DOI: 10.1542/pir.2024-006701 AbstractBronchopulmonary dysplasia (BPD) remains a significant source of morbidity and mortality among preterm infants, especially those born before 28 weeks gestation. Although the survival of preterm infants has improved, the incidence of

Bronchopulmonary Dysplasia: A Contemporary Review for Pediatric Practice Read More »

Lactobacillus Is Associated With Disease in Pulmonary Arterial Hypertension: A Prospective Cohort Study

Arun Jose, Senu Apewokin, Nicholas J. Ollberding, Qing Duan, Jennifer Trannguyen, Sasha Z. Prisco, Thenappan Thenappan, Anna R. Hemnes, Jean M. ElwinUniversity of Cincinnati and Cincinnati Children’s Hospital Medical Center. University of Minnesota. Vanderbilt University.United States Comprehensive PhysiologyComp Physiol 2026; 16: DOI: 10.1002/cph4.70161 AbstractBackground: Gut dysbiosis and gut-derived metabolites have been linked to pulmonary arterial hypertension. However,

Lactobacillus Is Associated With Disease in Pulmonary Arterial Hypertension: A Prospective Cohort Study Read More »

Plasma Asymmetric Dimethylarginine as a Biomarker of Disease Severity and Therapeutic Response in Neonatal Persistent Pulmonary Hypertension: An Observational Prospective Case-Control Study

Rania M Abdou, Maged A. El Wakeel, Ghada M. El-Kassas, Walaa H. Ali, Hend M. Ahmed, Mohamed Agha, Mohamed Abdel Atti Abdel Fatah, Ramy Saleh Abdelghany, Kareem Salah Eldin Fekry Madbouly, Haidy Badei Mohamad, Iman Shawky Hassan, Mohamed Abdelsalam Mohamed Ahmed, Heba T. Okda, Hatem Attia Mostafa Ismail Ain Shams University. Child Health Department, National

Plasma Asymmetric Dimethylarginine as a Biomarker of Disease Severity and Therapeutic Response in Neonatal Persistent Pulmonary Hypertension: An Observational Prospective Case-Control Study Read More »

Inflachromene attenuates monocrotaline-induced pulmonary arterial hypertension by suppressing the HMGB1-TLR4/RAGE-NF-κB signaling pathway

Yueru Wang, Dina Nuerlan, Bilali Paizula, Yimuran Kawulijiang, Jiyao Chen, Hong Zhu, Wentao Xiao, Zhayier Tueraili, Guoming ZhangFirst Affiliated Hospital of Xinjiang Medical University. Second Affiliated Hospital of Xinjiang Medical University. First Affiliated Hospital of Shihezi University.China International ImmunopharmacologyInt Immunopharmacol 2026; DOI: 10.1016/j.intimp.2026.116712 AbstractPulmonary arterial hypertension (PAH) is a debilitating and fatal cardiovascular disorder marked by

Inflachromene attenuates monocrotaline-induced pulmonary arterial hypertension by suppressing the HMGB1-TLR4/RAGE-NF-κB signaling pathway Read More »