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Incidence and risk factors of pulmonary hypertension in neonates with congenital diaphragmatic hernia: a systematic review and meta-analysis

Rebeca Lopes Figueira, Fabian Doktor, Nazgol Moheimani, Giuseppe Lauriti, Jessie Lu, Giuseppe Speziale, Augusto ZaniHospital for Sick Children. Washington University School of Medicine. University of Leipzig Medical Center. “G. d’Annunzio” University of Chieti-Pescara, “Spirito Santo” Hospital of Pescara. Canada, United States, Germany and Italy Pediatric Surgery InternationalPediatr Surg Int 2025; 42: DOI: 10.1007/s00383-025-06247-9 AbstractPurpose: Pulmonary hypertension secondary […]

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Mitophagy-associated biomarkers and macrophage involvement in pulmonary arterial hypertension: identification and functional implications

Xiaoyu Zhang, Liming Cheng, Jiahui Xie, Xuejuan Ma, Wenting Gui, Jiaxiang Chen, Kai Liu, Runwei MaFuwai Yunnan Hospital, Kunming Children’s Hospital, Chinese Academy of Medical Sciences and Affiliated Cardiovascular Hospital of Kunming Medical University. China Frontiers in PhysiologyFront Physiol 2025; 14: DOI: 10.3389/fphys.2025.1673181 AbstractBackground: Pulmonary arterial hypertension (PAH) is a progressive disorder characterized by pulmonary vascular remodeling

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Secondary pulmonary hypertension in an adult patient with Ebstein anomaly post-atrial septal defect closure; can it be reversible? A case report

Ahmed Kheiwa, Vandad Saadat, Joseph Chung, Stephen Nageotte, Anees RazzoukLoma Linda University Medical Center. European Heart Journal Case ReportsEur Heart J Case Rep 2025; 9: DOI: 10.1093/ehjcr/ytaf527 AbstractBackground: Pulmonary hypertension is often a difficult to diagnose condition, in particular in younger population of patients. Early diagnosis and treatment of this condition is crucial to prevent further morbidity

Secondary pulmonary hypertension in an adult patient with Ebstein anomaly post-atrial septal defect closure; can it be reversible? A case report Read More »

Interaction of circPcmtd1 with HSP90AB1 mediates phosphorylation of AKT to regulate pulmonary arterial hypertension induced by high pulmonary blood flow in rat

Bingbing Ye, Danyan Su, Yuqin Huang, Dongli Liu, Yanyun Huang, Suyuan Qin, Cheng Chen, Yusheng PangFirst Affiliated Hospital of Guangxi Medical University.China Clinical and Experimental HypertensionClin Exp Hypertens 2025; 47: DOI: 10.1080/10641963.2025.2583193 AbstractThis study was designed to elucidate the role of circPcmtd1 in regulating pulmonary artery smooth muscle cells (PASMCs) proliferation and migration, through the HSP90AB1/AKT

Interaction of circPcmtd1 with HSP90AB1 mediates phosphorylation of AKT to regulate pulmonary arterial hypertension induced by high pulmonary blood flow in rat Read More »

Lymphocytes and immunoglobulins in peripheral blood and lymphatic fluid of neonates with chylothorax

Domenico Umberto De Rose, Francesca Landolfo, Flaminia Pugnaloni, Fatima Zahra Gassabi, Ludovica Martini, Alessandra Santisi, Claudia Columbo, Paola Giliberti, Fabia Gazzotti, Ottavia Porzio, Claudia Capponi, Carlo Federico Perno, Maria Paola Ronchetti, Andrea Conforti, Guglielmo Salvatori, Irma Capolupo, Andrea Dotta“Bambino Gesù” Children’s Hospital IRCCS. “Tor Vergata” University of Rome. Italy Frontiers in ImmunologyFront Pediatr 2025; 16:

Lymphocytes and immunoglobulins in peripheral blood and lymphatic fluid of neonates with chylothorax Read More »

KBG syndrome complicated with chylothorax in a newborn: a case report and literature review

Yuqian Wang, Xin Peng, Jing Zhu, Ning Zou, Xiaotong Yu, Liu YangSecond Hospital of Dalian Medical University. Dalian Women and Children’s Medical Group. China Frontiers in PediatricsFront Pediatr 2025; 13: DOI: 10.3389/fped.2025.1690056 AbstractObjective: To discuss a unique case of KBG syndrome (KBGS) in neonates that developed congenital chylothorax and to examine how ANKRD11 gene variations may be related to

KBG syndrome complicated with chylothorax in a newborn: a case report and literature review Read More »

Characterizing Periprocedural Care for Pediatric Patients With Williams Syndrome Undergoing General Anesthesia at a Tertiary Pediatric Hospital

Laura K. Andrews, Reid C. Chamberlain, Susan Silva, Remi Hueckel, Desi Newberry, Warwick Ames, Emily M. FunkUniversity of North Carolina Southeastern Hospital. Duke Children’s Hospital and Health Center and Duke University.United States American Association of Nurse Anesthesiology JournalAANA J 2025; 93: 273-282DOI: 10.70278/AANAJ/.0000001030 AbstractWilliams syndrome is a rare congenital disorder affecting connective tissue and the cardiovascular

Characterizing Periprocedural Care for Pediatric Patients With Williams Syndrome Undergoing General Anesthesia at a Tertiary Pediatric Hospital Read More »

Fetal Ductal Constriction, Pulmonary Hypertension and Atrial Septum Mobility: A Correlation Study

Paulo Zielinsky, Polyanna Henriques, Pedro Van Der Sand, Maria Antonia Saldanha, Gabriela Macelaro, Joana NicolosoFundação Universitária de Cardiologia-IC/FUC. Universidade Federal do Rio Grande do Sul-UFRGS.Brazil Journal of Ultrasound in MedicineJ Ultrasound Med 2025; DOI: 10.1002/jum.70130 AbstractObjectives: Fetuses with ductal constriction (FDC), pulmonary hypertension and right ventricular overload after maternal exposure to PGE2 inhibitors-nonsteroidal anti-inflammatory drugs (NSAIDs) or

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Transthoracic Echocardiographic Markers of Pulmonary Vein Stenosis Requiring Transcatheter Intervention in Premature Infants

Samantha Holmes, Ernesto Meija, Morgan MacBeth, Jenny Zablah, Benjamin S. FrankUniversity of Colorado School of Medicine. Manning Family Children’s. United States Pediatric CardiologyPediatr Cardiol 2025; DOI: 10.1007/s00246-025-04099-7 AbstractPulmonary vein stenosis (PVS) is a challenging diagnosis, especially in premature infants. Echocardiography is often used as the primary screening tool in this population, but its accuracy in identifying

Transthoracic Echocardiographic Markers of Pulmonary Vein Stenosis Requiring Transcatheter Intervention in Premature Infants Read More »

Sepsis in the Structurally-Vulnerable Heart: A Case of Infective Endocarditis Masquerading as a Urinary Tract Infection in Pediatric Rheumatic Heart Disease

Anna Mikami, Michael Sherwood, Abrag Nassar, Jennifer Burnham, Miriam Benavides, Samhrutha Sripathi, Chezhiyan MurugesanKern Medical Center.United States CureusCureus 2025; 17: DOI: 10.7759/cureus.94673 AbstractWe present a case of a six-year-old female patient with a history of rheumatic heart disease (RHD), including mitral stenosis, mitral regurgitation, and pulmonary hypertension, who presented with fever, abdominal pain, and urinary findings.

Sepsis in the Structurally-Vulnerable Heart: A Case of Infective Endocarditis Masquerading as a Urinary Tract Infection in Pediatric Rheumatic Heart Disease Read More »

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