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A germline chimeric KANK1-DMRT1 transcript derived from a complex structural variant is associated with a congenital heart defect segregating across five generations

Silvia Souza da Costa, Veniaminn Fishman, Mara Pinheiro, Andre Rodrigueiro, Maria Teresa Sanseverino, Paulo Zielinsky, Claudia M. B. Carvalho, Carla Rosenberg, Ana Cristina Victorino KrepischiUniversity of São Paulo. Siberian Branch of the Russian Academy of Sciences. Uniscience do Brasil. Hospital de Clínicas de Porto Alegre. Pontifícia Universidade Catolica do Rio Grande Do Sul. Federal University […]

A germline chimeric KANK1-DMRT1 transcript derived from a complex structural variant is associated with a congenital heart defect segregating across five generations Read More »

Right ventricular fibrosis in adults with uncorrected secundum atrial septal defect and pulmonary hypertension: a cardiovascular magnetic resonance study with late gadolinium enhancement, native T1 and extracellular volume

Fatwiadi Apulita Ginting Munte, Elen Elen,Olfi Lelya, Estu Rudiktyo, Radityo Prakoso, Oktavia LilyasarUniversity of Indonesia. Indonesia Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2024; DOI: 10.3389/fcvm.2024.1395382 AbstractIntroduction: Right ventricular (RV) fibrosis represents both adaptive and maladaptive responses to the overloaded RV condition. Its role in pulmonary hypertension (PH) associated with secundum atrial septal defect (ASD), which is the

Right ventricular fibrosis in adults with uncorrected secundum atrial septal defect and pulmonary hypertension: a cardiovascular magnetic resonance study with late gadolinium enhancement, native T1 and extracellular volume Read More »

Viscosity Corrected Pulmonary Resistance Index in Paediatric Pulmonary Arterial Hypertension

Zhouyuan Xu, Qiangqiang Li, Chen Zhang, Qiang Wang, Hong Gu, Yihua HeBeijing An Zhen Hospital. China American Journal of Respiratory and Critical Care MedicineAm J Respir Crit Care Med 2024; DOI: 10.1164/rccm.202401-0234LE AbstractAbstract Not Available CategoryDiagnostic Testing for Pulmonary Vascular Disease. Invasive Testing Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Filed (PHiled). Greater

Viscosity Corrected Pulmonary Resistance Index in Paediatric Pulmonary Arterial Hypertension Read More »

Pulmonary hypertension in the intensive care unit after pediatric allogeneic hematopoietic stem cell transplant: incidence, risk factors, and outcomes

Michael A. Smith, Geoffrey Cheng, Rachel Phelan, Ruta Brazauskas, Joelle Strom, Kwang Woo Ahn, Betty Ky Hamilton, Andrew Peterson, Bipin Savani, Hélène Schoemans, Michelle L. Schoettler, Mohamed Sorror, Roberta L. Keller, Christine S. Higham, Christopher C. Dvorak, Jeffrey R. Fineman, Matt S. ZinterUniversity of California, San Francisco. Medical College of Wisconsin. Cleveland Clinic. Vanderbilt University

Pulmonary hypertension in the intensive care unit after pediatric allogeneic hematopoietic stem cell transplant: incidence, risk factors, and outcomes Read More »

Collagen 18A1/Endostatin Expression in the Progression of Right Ventricular Remodeling and Dysfunction in Pulmonary Arterial Hypertension

Anjira S. Ambade, Mario Naranjo, Tijana Tuhy, Rose Yu, Mery Marimoutou, Allen D. Everett, Larissa A. Shimoda, Stefean L. Zimmerman, Ilton M. Cubero Salazar, Catherine E. Simpson, Ryan J. Tedford, Steven Hsu, Paul M. Hassoun, Rachel L. DamicoJohns Hopkins University. Temple University. Johns Hopkins Community Physicians. Institute for In Vitro Sciences Inc. Medical University of

Collagen 18A1/Endostatin Expression in the Progression of Right Ventricular Remodeling and Dysfunction in Pulmonary Arterial Hypertension Read More »

Elevated pulmonary capillary wedge pressure, higher blood pressure, and lower cardiac index in infants with bronchopulmonary dysplasia

Cathereine M. Avitable, Xuemei Zhang, Steve Ampah, Yan Wang, Devon Ash, Kathleen Nilan, Jennifer E. Tingo, David B. Frank, Erik A. Jensen, Krithika Lingappan, Kathleen A. GibbsThe Children’s Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania. United States Internation Journal of CardiologyInt J Cardiol 2024; DOI: 10.1016/j.ijcard.2024.132246 AbstractBackground: Left ventricular diastolic dysfunction

Elevated pulmonary capillary wedge pressure, higher blood pressure, and lower cardiac index in infants with bronchopulmonary dysplasia Read More »

Pediatric high-altitude pulmonary edema and acute mountain sickness: Clinical features and risk determinants

Yu-Mei Mi, Wei-Lin Hu, Hua-Mao Chao, Chun-Zhen Hua, Zhi-Min ChenChildren’s Hospital and Zhejiang University School of Medicine. People’s Hospital of Haixi Autonomous Prefecture of Qinghai Province. China Pediatric PulmonologyPediatr Pulmonol 2024; DOI: 10.1002/ppul.27101 AbstractObjective: This investigation aimed to delineate the clinical manifestations associated with high-altitude pulmonary edema (HAPE) and acute mountain sickness (AMS) in pediatric populations and

Pediatric high-altitude pulmonary edema and acute mountain sickness: Clinical features and risk determinants Read More »

Cardiorenal Syndrome in Right Heart Failure Due to Pulmonary Arterial Hypertension-The Right Ventricle as a Therapeutic Target to Improve Renal Function

Kenzo Ichimura, Adam Gross, Roy O. Mathew, Loay Salman, Sushma Reddy, Edda Spiekerkoetter, Mandeep S. SidhuStanford University. Albany Medical College. Loma Linda VA Health Care System. United States Cardiovascular Drugs and TherapyCardiovasc Drugs Ther 2024; DOI: 10.1007/s10557-024-07588-8 AbstractCardiorenal syndrome (CRS) due to right ventricular (RV) failure is a disease entity emerging as a key indicator of

Cardiorenal Syndrome in Right Heart Failure Due to Pulmonary Arterial Hypertension-The Right Ventricle as a Therapeutic Target to Improve Renal Function Read More »

Resistin predicts disease severity and survival in patients with pulmonary arterial hypertension

Li Gao, John Skinner, Tanmay Nath, Qing Lin, Megan Griffiths, Rachel L. Damico, Michael W. Pauciulo, William Nichols, Paul M. Hassoun, Allen Everett, Roger A. JohnsJohns Hopkins University School of Medicine. University of Texas Southwestern Medical Center. Cincinnati Children’s Hospital Medical Center and University of Cincinnati. United States Respiratory ResearchRespir Res 2024; 25: DOI: 10.1186/s12931-024-02861-8 AbstractBackground: Abnormal

Resistin predicts disease severity and survival in patients with pulmonary arterial hypertension Read More »

Aberrant PGC-1α signaling in a lamb model of persistent pulmonary hypertension of the newborn

Emily A. Mooers, Hollis M. Johnson, Teresa Michalkiewicz, Ujala Rana, Chintamani Joshi, Adeleye J. Afolayan, Ru-Jeng Teng, Girija G. KonduriMedical College of Wisconsin.United States Pediatric ResearchPediatr Res 2024; DOI: 10.1038/s41390-024-03223-2 AbstractBackground: Persistent Pulmonary Hypertension of the Newborn (PPHN) is characterized by elevated pulmonary vascular resistance (PVR), resulting in hypoxemia. Impaired angiogenesis contributes to high PVR. Pulmonary artery

Aberrant PGC-1α signaling in a lamb model of persistent pulmonary hypertension of the newborn Read More »

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