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The prediction value of serum anion gap for short-term mortality in pulmonary hypertension patients with sepsis: a retrospective cohort study

Jinhua Zhu, Zeying Zhang, Yefei Lei, Zhenrong Ouyang, Shelby Kutty, Qiming Liu, Yunbin XiaoFirst People’s Hospital of Chenzhou and Hunan Children’s Hospital Affiliated to Jinan University. Xiamen Cardiovascular Hospital of Xiamen University. Johns Hopkins School of Medicine. Second Xiangya Hospital and Affiliated Children’s Hospital of Central South University. China Frontiers in MedicineFront Med 2025; 11: DOI: 10.3389/fmed.2024.1499677 AbstractBackground: The […]

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The clinical assessment of lung involvement in patients with Still’s disease, results from the multicentre international AIDA Network Still’s Disease Registry

Piero Ruscitti 1, Antonio Vitale 2 3, Ilenia Di Cola 1, Valeria Caggiano 2 3, Pierpaolo Palumbo 4, Ernesto Di Cesare 1, Andrea Hinojosa-Azaola 5, Jiram Torres-Ruiz 5, Guillermo Arturo Guaracha-Basañez 5, Eduardo Martín-Nares 5, Giuseppe Lopalco 6, Maria Morrone 6, Florenzo Iannone 6, Henrique A Mayrink Giardini 7, Rafael Alves Cordeiro 7, Isabele Parente de Brito Antonelli 7, Onorina Berardicurti 8 9, Luca Navarini 8 9, Francesco Ciccia 10, Maria Chiara Visconti 10, Daniela Iacono 10, Haner Direskeneli 11, Sukran Erten 12, Haihong Yao 13, Maissa Thabet 14, Samar Tharwat 15 16, Gaafar Ragab 17 18, Verónica Gómez-Caverzaschi 19, Petros P Sfikakis 20, Lampros Fotis 21, Francesco La Torre 22, Armin Maier 23, Anastasios Karamanakos 24, Ibrahim A Almaghlouth 25 26, Micol Frassi 27, Abdurrahman Tufan 28, Marcello Govoni 29, Jurgen Sota 2 3, Gabriele Simonini 30, Giacomo Emmi 31 32, Francesca Li

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Novel Therapies for Right Ventricular Failure

Bibhuti B. DasUniversity of Mississippi Medical Center.United States Current Cardiology ReportsCurr Cardiol Rep 2025; 27:DOI: 10.1007/s11886-024-02157-9 AbstractPurpose of review: Traditionally viewed as a passive player in circulation, the right ventricle (RV) has become a pivotal force in hemodynamics. RV failure (RVF) is a recognized complication of primary cardiac and pulmonary vascular disorders and is associated with a

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[Prognosis of bronchopulmonary dysplasia]

Ying-Zhen Zhou, Ting Wang, Xing-Meng Fu, Bing-Ming Peng, Zhou FuChildren’s Hospital of Chongqing Medical University and National Clinical Research Center for Child Health and Disorders.China Chinese Journal of Contemporary PediatricsZhongguo Dang Dai Er Ke Za Zhi 2025; 27: 115-120DOI: 10.7499/j.issn.1008-8830.2406004 AbstractChildren with bronchopulmonary dysplasia (BPD) often exhibit severe respiratory problems and significant pulmonary dysfunction during school

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Endogenous hydrogen sulfide persulfidates endothelin type A receptor to inhibit pulmonary arterial smooth muscle cell proliferation

Yanan Zhang, Xiaoyu Tiana, Liangyi Chenb, Shiqun Zhaob, Xinjing Tang, Xin Liu, Dan Zhou, Chaoshu Tang, Bin Geng, Junbao Dua, Hongfang Jina, Yaqian HuangPeking University First Hospital and Peking University. Wuhan Children’s Hospital. Fuwai Hospital and Peking Union Medical College. China Redox BiologyRedox Biol 2025; 80: DOI: 10.1016/j.redox.2025.103493 AbstractBackground: The binding of endothelin-1 (ET-1) to endothelin type

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Mortality Patterns in Pediatric Pulmonary Vein Stenosis: Insights Into Right Ventricular Systolic Pressure Associations

Daiji Takajo, Paul J. Critser, Michelle Cash, Melissa Magness, Russel HirschCincinnati Children’s Hospital Medical Center and University of Cincinnati.United States Journal of the American Heart AssociationJ Am Heart Assoc 2025; DOI: 10.1161/JAHA.124.037908 AbstractBackground: Pulmonary vein stenosis in children is associated with a poor prognosis. However, the cause and risk factors for mortality remain uncertain.Methods: This retrospective, single-center study

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Amniotic fluid stem cell extracellular vesicles as a novel fetal therapy for pulmonary hypoplasia: a review on mechanisms and translational potential

Fabian Doktor, Lina Antounians, Rebeca Lopes Figueira, Kasra Khalaj, Miriam Duci, Augusto ZaniHospital for Sick Children and University of Toronto. Leipzig University.Canada and Germany Stem Cells Translational MedicineStem Cells Transl Med 2025; 14: DOI: 10.1093/stcltm/szae095 AbstractDisruption of developmental processes affecting the fetal lung leads to pulmonary hypoplasia. Pulmonary hypoplasia results from several conditions including congenital diaphragmatic

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Postnatal management of preterm infants with congenital diaphragmatic hernia

Emma Williams, Stephanie Lau, Nimrah Abbasi, Eveline Lapidus-Krol, Priscilla P. L. Chiu, Brian T. KalishHospital for Sick Children and University of Toronto. Mount Sinai Hospital. Canada Pediatric Surgery InternationalPediatr Surg Int 2025; 41: DOI: 10.1007/s00383-025-05964-5 AbstractIntroduction: Congenital diaphragmatic hernia (CDH) in the preterm population is increasingly common in the current era of fetal endoluminal tracheal occlusion (FETO)

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Reversed valved Potts shunt for refractory primary pulmonary arterial hypertension

Sebastian Michel, Joseph Pattathu, Jürgen Hörer, Fabian A. KariLMU University Hospital. Gernany Multimedia Manual of Cardio-thoracic SurgeryMultimed Man Cardiothorac Surg 2025; DOI: 10.1510/mmcts.2024.120 AbstractThis procedure is carried out via a full sternotomy using standard aortic and bicaval cannulations. For the aortic and pulmonary anastomoses, selective antegrade unilateral cerebral perfusion is used after cooling the body temperature

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Systemic Sirolimus Therapy Is Associated With Reduced Intervention Frequency in Pulmonary Vein Stenosis

Alyssa B. Kalustian, Joseph L. Hagan, Paige E. Brlecic, Ionela Iacobas, Rachel D. Vanderlaan, Joseph Burns, Thao T. Wu, Ravi Birla, Sharada Gowda, Manish Bansal, Srinath T. Gowda, Lindsay F. Eilers, Asra Khan, Juan Pablo Sandoval-Jones, Michiaki Imamura, Yishay Orr, Christopher A. Caldarone, Athar M. QureshiTexas Children’s Hospital and Baylor College of Medicine. Hospital for

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