Medical Therapy. Efficacy or Lack of Efficacy

Association between immediate oxygenation response and survival in preterm infants receiving rescue inhaled nitric oxide therapy for hypoxemia from pulmonary hypertension: A systematic review and meta-analysis

Michelle Baczynski, Bonny Jasani, Charmaine De Castro, Carlo Dani, Nimish V. Subhedar, Praveen Chandrasekharan, Satvan Lakshminrusimha, Patrick J. McNamara, Adrianne R. Bishchoff, Amish JainMount Sinai Hospital. Hospital for Sick Children. Careggi University Hospital of Florence and University of Florence. Liverpool Women’s Hospital. University at Buffalo. UC Davis Children’s Hospital. University of Iowa. Canada, Italy, United […]

Association between immediate oxygenation response and survival in preterm infants receiving rescue inhaled nitric oxide therapy for hypoxemia from pulmonary hypertension: A systematic review and meta-analysis Read More »

Intra-amniotic sildenafil treatment improves lung blood flow and pulmonary hypertension in congenital diaphragmatic hernia rats

Shiho Yoshida, Alexander M. Kreger, George K. Gittes UPMC Children’s Hospital of Pittsburgh and University of Pittsburgh School of Medicine.United States Frontiers in Bioengineering and BiotechnologyFront Bioeng Biotechnol 2023; DOI: 10.3389/fbioe.2023.1195623 AbstractPulmonary hypertension associated with congenital diaphragmatic hernia (CDH) is a critical factor in determining prognosis. We propose that intra-amniotic sildenafil administration is an effective prenatal therapy for

Intra-amniotic sildenafil treatment improves lung blood flow and pulmonary hypertension in congenital diaphragmatic hernia rats Read More »

Spontaneous neonatal pulmonary arterial thrombosis – cases, mechanisms, and literature review

Ali Abdelhafiz, Alexis L. Benscoter, Sarosh P. BatlivalaCincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine.United States Cardiology in the YoungCardiol Young 2023; DOI: 10.1017/S1047951123002639 AbstractSpontaneous pulmonary artery thrombosis in neonates is rare and can be life-threatening. Clinical presentation may mimic pulmonary hypertension or CHD. Further, not all children present with identifiable risk

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Vasopressin versus epinephrine during neonatal cardiopulmonary resuscitation of asphyxiated post-transitional piglets

Megan O’Reilly, Tze-Fun Lee, Po-Yin Cheung, Georg M. SchmolzerRoyal Alexandra Hospital and University of Alberta.Canada Resuscitation PlusResus Plus 2023; 15DOI: 10.1016/j.resplu.2023.100427 AbstractBackground: Epinephrine is currently the only recommended cardio-resuscitative medication for use in neonatal cardiopulmonary resuscitation (CPR), as per the consensus of science and treatment recommendations. An alternative medication, vasopressin, might be beneficial in neonatal CPR due

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Drug-eluting stents ameliorate pulmonary vein stenotic changes in pigs in vivo

Takeshi Furukawa, Masahiko Kishiro, Hideo Fukunaga, Masahiro Ohtsuki, Ken Takahashi, Katsumi Akimoto, Toshiaki Shimizu, Shiori Kawasaki, Toshio KumasakaJuntendo University School of Medicine.Japan Pediatric CardiologyPediatr Cardiol 2010; 31: 773-779DOI: 10.1007/s00246-010-9695-8 AbstractThe outcome of stent implantation for pulmonary vein stenosis (PVS) in children remains poor. Several reports describe placing drug-eluting stents to treat PVS, but their effectiveness remains

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First experience with a new drug-eluting balloon for the treatment of congenital pulmonary vein stenosis in a neonate

Goetz Christoph Mueller, Ali Dodge-Khatami, Jochen WeilUniversity Heart Center Hamburg.Germany Cardiology in the YoungCardiol Young 2010; 20: 455-458DOI: 10.1017/S1047951110000703 AbstractPaclitaxel-eluting balloons are a new and innovative method in the treatment of in-stent stenosis and small vessel disease in adult cardiac pathology. The treatment of congenital pulmonary vein stenosis is difficult to manage, and results in a

First experience with a new drug-eluting balloon for the treatment of congenital pulmonary vein stenosis in a neonate Read More »

Losartan ameliorates “upstream” pulmonary vein vasculopathy in a piglet model of pulmonary vein stenosis

Jiaquan Zhu, HarukiIde, Yaqin Yana Fu, Anouk-Martine Teichert, Hideyuki Kato, Richard D. Weisel, Jason T. Maynes, John G. Coles, Christopher A. CaldaroneThe Hospital for Sick Children and University of Toronto. Toronto General Hospital. Canada Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2014; 148: 2550-2557DOI: 10.1016/j.jtcvs.2014.07.050 AbstractObjectives: Pulmonary vein stenosis (PVS) is a relentless disease with

Losartan ameliorates “upstream” pulmonary vein vasculopathy in a piglet model of pulmonary vein stenosis Read More »

Pulmonary hypertension associated with acute or chronic lung diseases in the preterm and term neonate and infant. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK

Anne Hilgendorff, Christian Apitz, Damien Bonnet, Georg HansmannDr von Haunersche Children’s Hospital. Children’s Hospital, University of Ulm. Hôpital Necker Enfants Malades, APHP, Université Paris Descartes. Hannover Medical School. Germany and France HeartHeart 2016; 102 Suppl 2: ii49-56DOI: 10.1136/heartjnl-2015-308591 AbstractPersistent pulmonary hypertension of the newborn (PPHN) is the most common neonatal form and mostly reversible after a few days

Pulmonary hypertension associated with acute or chronic lung diseases in the preterm and term neonate and infant. The European Paediatric Pulmonary Vascular Disease Network, endorsed by ISHLT and DGPK Read More »

[Diffuse pulmonary lymphangiomatosis with pleural and pericardial involvement. Pediatric case report]

Rodolfo P. Moreno, Yanina Hernández, Patricia Garrido, Bethy Camargo Vargas, Alberto Hernández, Javier Faín, Cecilia Seligra, Patricia Topp, Alberto Maffey, Gustavo CardigniSanatorio de la Trinidad Palermo. Argintina Archives of Argentina PediatricsArch Argent Pediatr 2021; 119: e264-e268DOI: 10.5546/aap.2021.e264 AbstractDiffuse pulmonary lymphangiomatosis is a rare disease characterized by marked proliferation and dilation of lymphatic vessels in the lungs,

[Diffuse pulmonary lymphangiomatosis with pleural and pericardial involvement. Pediatric case report] Read More »

Midodrine, an Oral Alpha-1 Adrenoreceptor Agonist, Successfully Treated Refractory Congenital Chylous Pleural Effusion and Ascites in a Neonate

Satoshi Tamaoka, Asami Osada, Takane Kin, Takeshi Arimitsu, Mariko HidaKeio University School of Medicine.Japan ChestChest 2021; 159: e189-e191DOI: 10.1016/j.chest.2020.10.071 AbstractA trisomy 21 neonate presented with congenital chylous pleural effusion and ascites that was refractory to conventional pharmacotherapy. Midodrine, an oral alpha-1-adrenoreceptor agonist, achieved remission of chylous effusion without any adverse effects. To the best of our

Midodrine, an Oral Alpha-1 Adrenoreceptor Agonist, Successfully Treated Refractory Congenital Chylous Pleural Effusion and Ascites in a Neonate Read More »

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