Medical Therapy. Efficacy or Lack of Efficacy

High Altitude Pulmonary Edema in a Healthy Pediatric Patient Traveling from Denver to Breckenridge

Matthew Adamo, Kayla E. Prokopakis, Todd BolotinMercy Health St. Elizabeth Boardman Hospital. Centura Health St. Anthony Breckenridge Mountain Clinic.United States Open Accaess Emergency MedicineOpen Access Emerg Med 2022; 14:DOI: 10.2147/OAEM.S334485 AbstractA healthy 11-year-old boy presented with headache, nausea, and cough to a clinic at 2926 meters of altitude one day after ascending from his home altitude […]

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Occurrence of hyperoxia during iNO treatment for persistent pulmonary hypertension of the newborn: a cohort study

Justine de Jager, Fleur Brouwer, Jeroen Reijman, Roel L. F. van der Palen, Sylke J. Steggerda, Remco Visser, Arjan B. te Pas, Janneke DekkerLeiden University Medical Center.Netherlands European Journal of PediatricsEur J Pediatr 2024;DOI: 10.1007/s00431-024-05506-6 AbstractHigh concentrations of oxygen are often needed to optimize oxygenation in infants with persistent pulmonary hypertension (PPHN), but this can also

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A Comprehensive Review of Inhaled Nitric Oxide Therapy: Current Trends, Challenges, and Future Directions

Divyanshi Kaplish, Jayant D. Vagha, Revat J. Meshram, Sham LohiyaJawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & ResearchIndia CureusCureus 2024; 16:DOI: 10.7759/cureus.53558 AbstractThis comprehensive review explores the multifaceted landscape of inhaled nitric oxide (iNO) therapy, tracing its historical evolution, mechanisms of action, clinical applications, challenges, and future directions. The nitric oxide signaling pathway,

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Administering Nitric Oxide (NO) with High Flow Nasal Cannulas: A Simple Method

Vladimir L. Cousin, Raphael Joye, Angelo PolitoUniversity of Geneva. Switzerland Advances in Respiratory MedicineAdv Respir Med 2024; 92(1):92-95DOI: 10.3390/arm92010012 AbstractInhaled nitric oxide (iNO) is a pulmonary vasodilator that plays an important clinical ICU role. The administration of iNO is usually performed through an endotracheal tube, but spontaneously breathing patients might also benefit from iNO administration. The

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Continuous Positive Airway Pressure in the Treatment of Pediatric High Altitude Pulmonary Edema: A Case Study

Ryan Hodnick, Michael L. Cohen, Joseph B. Loehner, Jennifer MazzantiTrans Aero Medevac. TriState CareFlight.United States Wilderness and Environmental MedicineWilderness Environ Med 2024; DOI: 10.1177/10806032231222003 AbstractTreatment of high altitude pulmonary edema (HAPE) can be challenging and is further complicated in the pediatric patient in the prehospital environment. The following case presents a decompensating pediatric patient with HAPE in the prehospital

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Therapy in pediatric pulmonary hypertension: memoire of an unfinished journey

Martin Hosking, Angela BatesUniversity of British Columbia. University of Alberta.Canada Canadian Journal of CardiologyCan J Cardiol 2024;DOI: 10.1016/j.cjca.2024.02.009 AbstractAbstract Not Available CategoryMedical Therapy. Efficacy or Lack of Efficacy Age Focus: Pediatric Pulmonary Vascular Disease Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since publication Article AccessFree PDF File or Full Text Article Available Through

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Long-term safety and tolerability of ambrisentan treatment for pediatric patients with pulmonary arterial hypertension: An open-label extension study

Dunbar Ivy, Maurice Beghetti, Ernesto Juaneda‑Simian, Ramiya Ravindranath, Mary Ann Lukas, Sandra Machlitt‑Northen, Nicola Scott, Jun Narita, Rolf M. F. BergerChildren’s Hospital Colorado. University Children’s Hospital HUG and University of Geneva. Hospital de Niños de la Santísma Trinidad. Glaxo-Smith-Kline. Osaka University Graduate School of Medicine. Beatrix Children’s Hospital, University Medical Center Groningen and University of

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[Risks of magistral preparations in pediatrics]

Charlotte Rosen, Caroline Jacqmart, Corinne Charlier, Maurice Beghetti, Marie-Christine SeghayeCentre Hospitalier Universitaire de Liège. Hôpitaux universitaires de Genève.Belgium and Switzerland Revue Medicale de LiegeRev Med Liege 2024; 79: 104-109DOI: Not Available AbstractVasoreactive pulmonary arterial hypertension (PAH) in children is a form of idiopathic PAH that responds to vasoreactive testing with nitric oxide (NO) by a

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Intra-Amniotic Sildenafil and Rosiglitazone Late in Gestation Ameliorate the Pulmonary Hypertension Phenotype in Congenital Diaphragmatic Hernia

Shino Yoshida, Olivia Eichelberger, Michael Ulis, Alexander M. Kreger, George K. Gittes, Joseph T. ChurchUniversity of Pittsburgh School of Medicine and UPMC Children’s Hospital of Pittsburgh. University of Michigan Medical School.United States Pediatric SurgeryPediatr Surg 2024;DOI: 10.1016/j.jpedsurg.2024.01.010 AbstractBackground: Pulmonary hypertension remains difficult to manage in congenital diaphragmatic hernia (CDH). Prenatal therapy may ameliorate postnatal pulmonary hypertension. We

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Younger age at initiation of subcutaneous treprostinil is associated with better response in pediatric Group 1 pulmonary arterial hypertension

Justin J. Kochanski, Jeffrey A. Feinstein, Michelle Ogawa, Victor Ritter, Rachel K. Hopper, Gregory T. AdamsonStanford University School of Medicine.United States Pulmonary CirculationPulm Circ 2024; DOI: 10.1002/pul2.12328 AbstractChildren with severe Group 1 pulmonary arterial hypertension (PAH) have an unpredictable response to subcutaneous treprostinil (TRE) therapy, which may be influenced by age, disease severity, or other unknown

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