Medical Therapy. Efficacy or Lack of Efficacy

Case Report: Selexipag in pediatric pulmonary hypertension: Initiation, transition, and titration

Jenna M. Faircloth, Neelam D. Bhatt, Corey A. Chartan, Ryan D. Coleman, Natalie Villafranco, Fadel E. Ruiz, Raysa Morales-Demori, Elise Whalen, Erin Ely, Rozmeen Fombin, Nidhy P. VargheseTexas Children’s Hospital and Baylor College of Medicine.United States Frontiers in PediatricsFront Pediatr 2023; 11: DOI: 10.3389/fped.2023.1050508 AbstractSelexipag, a selective prostacyclin receptor agonist, is approved for treating pulmonary arterial […]

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Paediatric acute respiratory distress syndrome: consider the role of lymphatics

Mimi Lu, Elena Cavazzoni, Hiran Selvadurai, Juerg Martin BurrenChildren’s Hospital at Westmead. University of Sydney Discipline of Child and Adolescent Health. Australia British Medical Journal Case ReportsBMJ Case Rep 2022; 15: DOI: 10.1136/bcr-2021-245543 AbstractWe present a case of a 7-day-old male infant with severe respiratory disease requiring venoarterial extracorporeal membrane oxygenation therapy with evidence of lymphangiectasia

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Sirolimus efficacy in the treatment of critically ill infants with congenital primary chylous effusions

Shreva Agarwal, Berkley Kingman Anderson, Priya Mahajan, Caraciolo J. Fernandes, Judith F. Margolin, Ionela IacobasTexas Children’s Hospital and Baylor College of Medicine.United States Pediatric Blood and CancerPediatr Blood Cancer 2022; 69: DOI: 10.1002/pbc.29510 AbstractBackground: Chylothorax can be a presenting symptom of complex lymphatic anomaly in children and is associated with significant respiratory morbidity. Historically, the traditional pharmacological

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Propranolol treatment for chylothorax after congenital cardiac surgery

Rozelle Corda, Sophia Chrisomalis-Dring, Sarah Crook, Carrie J. Shawber, June K. Wu, Paul J. ChaiNew York Presbyterian/Morgan Stanley Children’s Hospital, Columbia University Irving Medical Center and Vagelos College of Physicians & SurgeonsUnited States Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2022; 163: 1630-1641DOI: 10.1016/j.jtcvs.2021.09.007 AbstractObjective: Postoperative chylothorax causes significant morbidities in pediatric patients with cardiac

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Neonatal lymphatic flow disorders: central lymphatic flow disorder and isolated chylothorax, diagnosis and treatment using novel lymphatic imaging and interventions technique

Deborah Rabinowitz, Kevin Dysart, Maxim ItkinNemours Children’s Hospital. Sidney Kimmel Medical College at Thomas Jefferson University. Perelman School of Medicine at the University of Pennsylvania. United States Current Opinion in PediatricsCurr Opin Pediatr 2022; 34: 191-196DOI: 10.1097/MOP.0000000000001109 AbstractPurpose of review: Neonatal lymphatic disorders (NLDs) are conditions that are relatively rare and difficult to treat. The recent development

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Treatment and outcomes of chylothorax in children: 20-year experience of a single institute

Kanokpan Ruangnapa, Wanaporn Anuntaseree, Kantara Saelim, Pharsai Prasertsan, Maneerat Puwanant, Supaporn DissanevatePrince of Songkla UniversityThailand Journal of Thoracic DiseaseJ Thorac Dis 2022; 14: 3719-3726DOI: 10.21037/jtd-22-474 AbstractBackground: Chylothorax is an uncommon cause of pleural effusion in children. This study aimed to determine the characteristics, treatment strategies, and outcomes of chylothorax in children from a single institute.Methods: The 65 episodes

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Assessing growth of infants with chylothorax receiving fortified skimmed human breast milk

Brittani Clark, Melissa Froh, Catherine Karls, Mary Beth Feuling, Praveen Goday, Michael Uhing, Stephanie S. Handler, T. Hang Nghiem-Rao, Elizabeth PolzinChildren’s Wisconsin and Medical College of Wisconsin.United States Nutrition in Clinical PracticeNutr Clin Pract 2023; 38: 199-203DOI: 10.1002/ncp.10887 AbstractLearning outcome: To learn how skimmed human milk (SHM) can be used in infants with chylothorax to support adequate

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Propranolol Therapy for Congenital Chylothorax

Roxane Handel-Orefice, Bevin Midura, June K. Wu, Elvira Parravicini, Russell S. Miller, Carrie J. ShawberColumbia University Vagelos College of Physicians and Surgeons and New York-Presbyterian Morgan Stanley Children’s HospitalUnited States PediatricsPediatrics 2023; 151: DOI: 10.1542/peds.2022-058555 AbstractCongenital chylothorax is a rare and often severe anomaly without well-established medical therapies. Previously, propranolol use in patients with lymphatic malformations

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Diagnosis and treatment of diffuse pulmonary lymphangioma in children: A case report

Xiaopu Sun, Chengyu Lu, Zhanhang Huang, Jiaxing Xu, Huiyi Zhu, Sen Yang, Deihui ChenThe First Affiliated Hospital of Guangzhou Medical University.China Experimental and Therapeutic MedicineExp Ther Med 2023; 25: DOI: 10.3892/etm.2023.11874 AbstractThe present study aimed to investigate the clinical characteristics of diffuse pulmonary lymphangioma (DPL) in children to improve the diagnosis and treatment of this disease.

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Effects of a Long-Term Wearable Activity Tracker-Based Exercise Intervention on Cardiac Morphology and Function of Patients with Cystic Fibrosis

Maria Anifanti, Stavros Giannakoulakos, Elpis Hatziagorou, Asterios Kampouras, John Tsanakas, Asterios Deligiannis, Evangelia KouidiAristotle University of Thessaloniki and Hippokration Hospital. Greece SensorsSensors 2022; 22: DOI: 10.3390/s22134884 AbstractSeveral studies have shown that patients with cystic fibrosis (CF), even at a young age, have pulmonary and cardiac abnormalities. The main complications are cardiac right ventricular (RV) systolic and/or

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