Zhuoyuan Xu, Yiwei Chen, Xiafeng, Yanjun Sun, Jie Bai, Zhuoming Xu, Lijun Fu, Hao Zhang
National Children’s Medical Center, Shanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Shanghai Institute of Pediatric Congenital Heart Disease.
China
Pulmonary Circulation
Pulm Circ 2026; 16:
DOI: 10.1002/pul2.70422
Abstract
We report the case of an 18-year-old female with progressive, end-stage pulmonary arterial hypertension (PAH) despite receiving maximal triple combination therapy. The patient had a history of patent ductus arteriosus (PDA) closure at 15 months of age. Due to a pulmonary hypertensive crisis during anesthesia induction, a transcatheter Potts procedure was successfully performed under extracorporeal membrane oxygenation (ECMO) support, involving covered stent implantation just below the previous PDA occluder. At the 3-month follow-up, the patient demonstrated significant clinical improvement, shifting to WHO class II-III, with a dramatic decrease in NT-proBNP (5406-512 pg/ml) and an increased 6-min walk distance (< 300 to 390 m). This case achieved short-term recovery of cardiac function and long-term maintenance of pulmonary vascular stability and demonstrates that the transcatheter Potts shunt is a feasible and effective life-prolonging treatment option for severe PAH, even in patients with a history of prior PDA closure.
Category
Class I. Pulmonary Hypertension Associated with Congenital Cardiovascular Disease
Surgical and Catheter-mediated Interventions for Pulmonary Vascular Disease
Age Focus: Pediatric Pulmonary Vascular Disease
Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication
Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: Yes