Pediatric Lung Transplantation for Pulmonary Vascular Diseases: Recent Advances and Challenges

Levent Midyat, Eleanor D. Muise, Gary A. Visner
University of Pittsburgh School of Medicine and Children’s Hospital of Pittsburgh. NYU Grossman School of Medicine and Hassenfeld Children’s Hospital. Harvard Medical School and Boston Children’s Hospital.
United states

Clinics in Chest Medicine
Clin Chest Med 2024; 45: 761-769
DOI: 10.1016/j.ccm.2024.02.023

Abstract
Pediatric lung transplantation for pulmonary vascular diseases has seen notable advancements and trends. Medical therapies, surgical options, and bridging techniques like extracorporeal membrane oxygenation and different forms of transplants have expanded treatment possibilities. Current challenges include ensuring patient adherence to post-transplant therapies, addressing complications like primary graft dysfunction and rejection, and conducting further research in less common conditions like pulmonary veno-occlusive disease and pulmonary vein stenosis. In this review article, the authors will explore the advancements, emerging trends, and persistent challenges in pediatric lung transplantation for pulmonary vascular diseases.

Category
Lung Transplantation for Pulmonary Vascular Disease
Class I. Idiopathic Pulmonary Hypertension
Class I. Heritable Pulmonary Hypertension
Class I. Pulmonary Hypertension Associated with Congenital Cardiovascular Disease
Class I. Pulmonary Veno-occlusive Disease and Pulmonary Capillary Hemangiomatosis
Class II. Pulmonary Hypertension Associated with Pulmonary Vein Stenosis
Review Articles Concerning Pulmonary Vascular Disease

Age Focus: Pediatric Pulmonary Vascular Disease

Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication

Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: No

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