John T. Wren, Jr., Rhucha Joshi, Patrick J. McNamara
University of Iowa Healthcare. Children’s Hospital of Orange County.
United States
Echocardiography
Echocardiography 2026; 43:
DOI: 10.1111/echo.70396
Abstract
Pulmonary hypertension (PH) in congenital diaphragmatic hernia (CDH) is nearly universal yet incredibly complex. A patent ductus arteriosus (PDA) is increasingly utilized to both monitor echocardiographically and manage CDH-PH. However, as pulmonary pressures are driven by both vascular resistance and blood flow, there is a risk that as the former improves, PH may in fact worsen from pathologic left-to-right (LtR) PDA shunting. Herein, we describe two cases of neonatal CDH whose PH was complicated by pathologic LtR PDA shunting and pulmonary overcirculation and improved following resolution of the transductal shunt, highlighting the underrecognized risk of pathologic PDA shunts in CDH.
Category
Class III. Pulmonary Hypertension Associated with Lung Hypoplasia
Class I. Pulmonary Hypertension Associated with Congenital Cardiovascular Disease
Diagnostic Testing for Pulmonary Vascular Disease. Non-invasive Testing
Age Focus: Pediatric Pulmonary Vascular Disease
Fresh or Filed Publication: Fresh (PHresh). Less than 1-2 years since publication
Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: No