Failure to Normalize Biventricular Function is Associated with Extracorporeal Membrane Oxygenation Use in Neonates with Congenital Diaphragmatic Hernia

Lisa S. Le, John P. Kinsella, Jason Gien, Benjamin Frank
Children’s Hospital Colorado and University of Colorado. 
United States

Journal of Pediatrics
J Pediatr 2023;
DOI: 10.1016/j.jpeds.2023.113490

Abstract
We examined post-natal echocardiograms for 62 congenital diaphragmatic hernia (CDH) infants born from 2014 through 2020. Left and right ventricular dysfunction on D0 were sensitive while persistent dysfunction on D2 was specific for extracorporeal membrane oxygenation (ECMO) requirement. Biventricular dysfunction had the strongest association with ECMO. Serial echocardiography may inform prognosis in CDH.

Category
Class III. Pulmonary Hypertension Associated with Lung Hypoplasia
Right Heart Dysfunction Associated with Pulmonary Vascular Disease
Diagnostic Testing for Pulmonary Vascular Disease. Non-invasive Testing

Age Focus: Pediatric Pulmonary Vascular Disease

Fresh or Filed Publication: Filed (PHiled). Greater than 1-2 years since publication

Article Access
Free PDF File or Full Text Article Available Through PubMed or DOI: No

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