Symptoms and Findings Associated with Pulmonary Vascular Disease

Brain Abscess and Stroke in Children and Adults With Hereditary Hemorrhagic Telangiectasia: Analysis of a Large National Claims Database

Andrew J. White, Itay Marmor, Kate M. Peacock, Katelin B. Nickel, Jessica Zavadil, Margaret A. OlsenSaint Louis University School of Medicine. Washington University School of Medicine.United States NeurologyNeurology 2023; DOI: 10.1212/WNL.0000000000207269 AbstractObjective: Hereditary hemorrhagic telangiectasia (HHT) is an inherited disease associated with pathogenic variants in TGF-β signaling pathway-related genes, resulting in abnormal vascular development in various organs. […]

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Effects of a Long-Term Wearable Activity Tracker-Based Exercise Intervention on Cardiac Morphology and Function of Patients with Cystic Fibrosis

Maria Anifanti, Stavros Giannakoulakos, Elpis Hatziagorou, Asterios Kampouras, John Tsanakas, Asterios Deligiannis, Evangelia KouidiAristotle University of Thessaloniki and Hippokration Hospital. Greece SensorsSensors 2022; 22: DOI: 10.3390/s22134884 AbstractSeveral studies have shown that patients with cystic fibrosis (CF), even at a young age, have pulmonary and cardiac abnormalities. The main complications are cardiac right ventricular (RV) systolic and/or

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Long-Term Study on Therapeutic Strategy for Treatment of Eisenmenger Syndrome Patients: A Case Series Study

Yi-Ching Liu, Yu-Wen Chen, I-Chen Chen, Yen-Hsien Wu, Shih-Hsing Lo, Jui-Sheng Hsu, Jong-Hau Hsu, Bin-Nan Wu, Yi-Fang Cheng, Zen-Kong DaiKaohsiung Medical University Hospital. Taiwan ChildrenChildren 2022; 9: DOI: 10.3390/children9081217 AbstractEisenmenger syndrome (ES) refers to congenital heart diseases (CHD) with reversal flow associated with increased pulmonary pressure and irreversible pulmonary vascular remodeling. Previous reports showed limited therapeutic

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Case Report: A Rare Syncope Case Caused by Abernethy II and a Review of the Literature

Xue-qin Lin, Jing-yi Rao, Yi-fei Xiang, Li-wei Zhang, Xiao-ling Cai, Yan-song Guo, Kai-yang LinShengli Clinical Medical College of Fujian Medical University and Fujian Provincial Hospital. Fujian Clinical Medical Research Center for Cardiovascular Diseases.China Frontiers in Cardiovascular DiseaseFront Cardiovasc Dis 2022; 8: DOI: 10.3389/fcvm.2021.784739 AbstractBackground: Abernethy malformation is an extremely rare anomaly of the splanchnic venous system, and

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Pregnancy outcomes of women with Eisenmenger syndrome: A single-center study

Yang Liu, Hong Gu, Yanna Li, Jun Zhang, Xiangming Fan, Yichen Zhao, Jiangang WangBeijing Anzhen Hospital affiliated to Capital Medical University. Hebei General Hospital. Zhejiang Children’s Hospital. China International Journal of CardiologyInt J Cardiol 2023; 374: 35-41DOI: 10.1016/j.ijcard.2022.12.014 AbstractBackground: To explore the outcomes of mothers with Eisenmenger syndrome (ES) and their offspring.Methods: Pregnant women with ES admitted to

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Exercise and hypoxia unmask pulmonary vascular disease and right ventricular dysfunction in a 10- to 12-week-old swine model of neonatal oxidative injury

Jarno J. Steenhorst, Alexander Hirsch, Annemarie Verzijl, Piotr Wielopolski, Daphne de Wijs-Meijler, Dirk J. Duncker, Irwin K. M. Reiss, Daphne MerkusUniversity Medical Center Rotterdam. University Clinic Munich. Munich Heart Alliance.Netherlands and Germany Journal of PhysiologyJ Physiol 2022; DOI: 10.1113/JP282906 AbstractPrematurely born young adults who experienced neonatal oxidative injury (NOI) of the lungs have increased incidence of

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Correlation Between Right Ventricular Echocardiography Measurements and Functional Capacity in Patients With Pulmonary Arterial Hypertension

Joyce L. Woo, Michael P. DiLorenzo, Eliana Rosenzweig, Nikhil Pasumarti, Gerson Valencia Villeda, Erika Berman-Rosenzweig, Usha KrishnanAnn and Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg School of Medicine. Columbia University Medical Center. Arnold Palmer Hospital for Children.United States Texas Heart Institute JournalTex Heart Inst J 2022; 49: DOI: 10.14503/THIJ-21-7719 AbstractBackground: Accelerometry is an

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Clinical differences between children and adults with idiopathic and heritable pulmonary arterial hypertension

Shinichi Takatsuki, Hiroto Shimokawahara, Yukira Shimizu, Reiko Kawai, Hiroyuki Matsuura, Hiromi MatsubaraToho University Omori Medical Center. National Hospital Organization Okayama Medical Center.Japan Cardiology in the YoungCardiol Young 2022; DOI: 10.1017/S1047951122003432 AbstractBackground: Although previous studies have demonstrated that paediatric pulmonary arterial hypertension remains distinct from that in adults, there are limited studies evaluating a direct comparison between children

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Vasoreactive phenotype in children with pulmonary arterial hypertension and syncope

Alexandra N. Linder, Jill Hsia, Sheila V. Krishnan, Erika B. Rosenzweig, Usha S. KrishnanColumbia University Irving Medical Center and New York Presbyterian Hospital. Children’s Hospital of Philadelphia, Philadelphia. Stonybrook University School of Medicine.United States European Respiratory Journal Open ResearchERJ Open Res 2022; 8: DOI: 10.1183/23120541.00223-2022 AbstractBackground: Syncope in Group 1 pulmonary arterial hypertension (PAH) is an independent

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Abnormal platelet aggregation in pediatric pulmonary hypertension

Stephanie S. Handler, Jing Jin, Michelle T. Ogawa, Jeffrey A. Feinstein, Clara LoMedical College of Wisconsin. Stanford University.United States Pulmonary CirculationPulm Circ 2022; 12: DOI: 10.1002/pul2.12104 AbstractEndogenous prostacyclin stimulates pulmonary vasodilation and inhibits platelet aggregation. For the synthetic analog treprostinil, used in the treatment of pulmonary hypertension (PH), conflicting, anecdotal evidence exists regarding its effects on

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