Pulmonary Arteriovenous Malformations

MiR-25-3p regulates pulmonary arteriovenous malformation after Glenn procedure in patients with univentricular heart via the PHLPP2-HIF-1α axis

Junpei Kawamura, Munekazu Yamakuchi, Kentaro Ueno, Teruto Hashiguchi, Yasuhiro OkamotoKagoshima University. Japan Scientific ReportsSci Rep 2025; 15: DOI: 10.1038/s41598-025-88840-5 AbstractThe detailed mechanism of pulmonary arteriovenous malformations after Glenn surgery (G-PAVMs) in cyanotic congenital heart disease (CHD) remains unclear. Microarray in situ hybridization was performed to assess the miRNA (miRNA) profiles of serum from pediatric patients (0-6 […]

MiR-25-3p regulates pulmonary arteriovenous malformation after Glenn procedure in patients with univentricular heart via the PHLPP2-HIF-1α axis Read More »

Embolotherapy for pulmonary arteriovenous malformations in the pediatric population with hereditary hemorrhagic telangiectasias – a retrospective case series

Haseeb Mukhtar, Vivek Iyer, Nadir Demirel, Emily C. Bendel, Haraldur Bjarnason, Sanjay MisraMayo Clinic.United States Journal of Vascular and Interventional RadiologyJ Vasc Interv Radiol 2025; DOI: 10.1016/j.jvir.2025.01.047 AbstractPurpose: To document the outcomes of embolotherapy for pulmonary arteriovenous malformation (pAVM) management, and investigate factors associated with pAVM persistence after embolotherapy in pediatric patients with hereditary hemorrhagic telangiectasia (HHT).Materials

Embolotherapy for pulmonary arteriovenous malformations in the pediatric population with hereditary hemorrhagic telangiectasias – a retrospective case series Read More »

Pulmonary vascular complications of cirrhosis: hepatopulmonary syndrome and portopulmonary hypertension

Maïté Verstraeten, Sander Lefere, Sarah RaevensGhent University Hospital and Ghent University.Belgium Acta Clinica BelgicaActa Clin Belg 2025; DOI: 10.1080/17843286.2025.2456697 AbstractHepatopulmonary syndrome (HPS) and portopulmonary hypertension (POPH) are two distinct pulmonary vascular complications seen in patients with liver disease and/or portal hypertension. HPS is characterized by disturbed gas exchange and hypoxemia because of intrapulmonary vascular dilatations. POPH

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Conservative Pulmonary Arteriovenous Malformation Screening in Children: Re-Evaluation of Safety

Fleur ten Berg, Josefien Hessels, Anna Hosman, Sanne Boerman, Marco C. Post, Walter A. F. Balemans, Hans-Jurgen MagerSt. Antonius Hospital. University Medical Centre Utrecht. Netherlands Pediatric PulmonologyPediatr Pulmonol 2025; 60: DOI: 10.1002/ppul.27476 AbstractIntroduction: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disease and screening to detect pulmonary arteriovenous malformations (PAVMs) is important to prevent complications. In

Conservative Pulmonary Arteriovenous Malformation Screening in Children: Re-Evaluation of Safety Read More »

Immersive 3-Dimensional Visualization Aids Transcatheter Management of a Patient With Multiple Pulmonary Arteriovenous Malformations

Aishwarya Gurav, Sarin Xavier, Harikrishnan Anil Maya, Rajiv Chandrasekharan, Raman Krishna Kumar, Mahesh KappanayilAmrita Institute of Medical Sciences.Kerala, India Journal of the American College of Cardiology Case ReportsJACC Case Rep 2024; 29: DOI: 10.1016/j.jaccas.2024.102480 AbstractCutting-edge 3-dimensional technologies like 3-dimensional printing and extended reality visualization provide novel, immersive ways to understand and interact with volumetric medical imaging

Immersive 3-Dimensional Visualization Aids Transcatheter Management of a Patient With Multiple Pulmonary Arteriovenous Malformations Read More »

Pulmonary arteriovenous malformation in children

Audrey Y. L. Lim, Felix RatjenHospital for Sick Children and University of Toronto.Canada Pediatric PulmonologyPediatr Pulmonol 2024; DOI: 10.1002/ppul.27354 AbstractPulmonary arteriovenous malformations (PAVMs) are rare abnormalities observed mainly in children with hereditary haemorrhagic telangiectasia (HHT). A majority of patients are asymptomatic at the time of detection. However, complications such as hypoxemia, stroke, cerebral abscess and massive

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CDK6-mediated endothelial cell cycle acceleration drives arteriovenous malformations in hereditary hemorrhagic telangiectasia

Sajeth Dinakaran, Sima Qutaina, Haitian Zhao, Yuefeng Tang, Zhimin Wang, Santiago Ruiz, Aya Nomura-Kitabayashi, Christine N. Metz, Helen M. Arthur, Stryder M. Meadows, Lionel Blanc, Marie E. Faughnan, Philippe MarambaudFeinstein Institutes for Medical Research and Northwell Health. Donald and Barbara Zucker School of Medicine at Hofstra/Northwell. Institut Pasteur de Montevideo. Newcastle University. Tulane University. Cohen

CDK6-mediated endothelial cell cycle acceleration drives arteriovenous malformations in hereditary hemorrhagic telangiectasia Read More »

Brain and lung arteriovenous malformation rescreening practices for children and adults with hereditary hemorrhagic telangiectasia

Lauren A. Beslow, Helen Kim, Steven W. Hetts, Felix Ratjen, Marianne S. Clancy, James R. Gossage, Marie E. FaughnanChildren’s Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania. University of California San Francisco. Hospital for Sick Children and University of Toronto. Cure HHT Foundation. Augusta University. St. Michael’s Hospital.United States and

Brain and lung arteriovenous malformation rescreening practices for children and adults with hereditary hemorrhagic telangiectasia Read More »

Glenn circulation causes early and progressive shunting in a surgical model of pulmonary arteriovenous malformations

Tina C. Wan, Henry Rousseau, Carol Mattern, Madeline Tabor, Matthew R. Hodges, Ramani Ramchandran, Andrew D. SpearmanMedical College of Wisconsin and Children’s Wisconsin.United States Physiological ReportsPhysiol Rep 2024; 12: DOI: 10.14814/phy2.70123 AbstractPulmonary arteriovenous malformations (PAVMs) universally develop in patients with single ventricle congenital heart disease. Single ventricle PAVMs have been recognized for over 50 years but

Glenn circulation causes early and progressive shunting in a surgical model of pulmonary arteriovenous malformations Read More »

Correction of Hemitruncus in an Adult Patient Alleviated Pulmonary Arteriovenous Fistula in the Affected Lung

Tomohiro Nakata, Maiko Tachi, Kenji Yasuda, Junya Tanabe, Yuka Kawanami, Kazuhiro YamazakiShimane University Faculty of Medicine. Japan World Journal of Pediatric and Congenital Heart SurgeryWorld J Pediatr Congenit Heart Surg 2024;  DOI: 10.1177/21501351241285452 AbstractWe present a case of a 36 year old adult with anomalous origin of the right pulmonary artery from the aorta (hemitruncus), pulmonary

Correction of Hemitruncus in an Adult Patient Alleviated Pulmonary Arteriovenous Fistula in the Affected Lung Read More »

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