Mechanical and Computer Models of Pulmonary Vascular Disease

The Pediatric Pulmonary Hypertension International Risk Score: A Prediction Model for Outcomes Using Machine Learning

Megan Griffiths, Bhargava K. Chinni, Chantel Lokhorst, Johannes M. Douwes, Lynn A. Sleeper, Jennifer Tingo, Steven H. Abman, Erika B. Rosenzweig, Jennifer E. Schramm, Eric D. Austin, Mary P. Mullen, Alba Torrent-Vernetta, Carlos Labrandero, Raymond Benza, Maria Jesus del Cerro, Rolf M. F. Berger, Cedric Manlhiot, Allen D. EverettUT Southwestern Medical Center. Johns Hopkins University. […]

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Development and validation of a nomogram prediction model for mild pulmonary arterial hypertension risk in children with left-to-right shunt congenital heart disease

Suyuan Qin, Lifeng Shang, Danyan Su, Bingbing Ye, Yuqin Huang, Yanyun Huang, Yusheng PangFirst Affiliated Hospital of Guangxi Medical University, Difficult and Critical Illness Center and the Pediatric Clinical Medical Research Center of Guangxi.China MedicineMedicine 2026; 105:DOI: 10.1097/MD.0000000000050136 AbstractMild pulmonary arterial hypertension (PAH) represents an early and potentially reversible complication stage in children with congenital structural

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Developing a Digital Twin of the Cardiopulmonary System in a Mouse: Inferring Hemodynamics from Sparse Measurements

Vitaly O. Kheyfets, Kenzo Ichimura, Paul M. Heerdt, Mengqian Zhang, Ella Lyon, Kurt R. Stenmark, Edda SpiekerkoetterUniversity of Colorado School of Medicine and University of Colorado Anschutz Medical Campus. Stanford University. Yale School of Medicine.United States Annals of Biomedical EngineeringAnn Biomed Eng 2026; DOI: 10.1007/s10439-026-04107-8 AbstractPurpose: The use of rodent models in the study of cardiopulmonary disease

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The Role of Machine Learning and Artificial Intelligence in Drug Discovery and Clinical Care of Pulmonary Hypertension

Evelyne Bischof, Chaim Haber, Niklas LidströmerShanghai University of Medicine and Health Sciences. Sheba Medical Center, Grey School of Medicine and Tel Aviv University. University of Copenhagen. Karolinska Institutet. China, Israel, Denmark and Sweden Heart Failure ClinicsHeart Fail Clin 2026; 22: 361-370DOI: 10.1016/j.hfc.2026.02.009 AbstractPulmonary hypertension (PH) is a severe and oftentimes fatal disease with a high degree

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A Biomimetic Miniaturized In Vitro Model to Target Early Markers of Neonatal Pulmonary Vascular Injury

Motaharehsadat Heydarian, Ali Doryab, Juan Henao, Benjamin Schubert, Otmar Schmid, Anne HilgendorffHelmholtz Zentrum München and German Lung Research Center. University of Cambridge. University Hospital Ludwig-Maximilian University. Carl von Ossietzky University.Germany and United Kingdom American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2026; DOI: 10.1152/ajplung.00002.2026 AbstractPulmonary vascular disease (PVD) is

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Adapting the REVEAL Lite 2 score to the pediatric population through machine learning: insights from the REHIPED registry for pediatric pulmonary hypertension

Julia Playán-Escribano, Carlos Labrandero de Lera, Leticia Albert de la Torre,  Alejandro Rodríguez-Ogando, Antonio Moreno-Galdó, Inmaculada Guillén Rodríguez, Anna Sabaté-Rotés, Amparo Moya-Bonora, Lina María Caicedo Cuenca, María Jesús del Cerro, on behalf of the REHIPED investigatorsHospital General Universitario Gregorio Marañón. Hospital Universitario del Sureste, Arganda del Rey. Universidad Complutense de Madrid. Hospital Universitario La Paz. Hospital Universitario 12 de Octubre. Hospital General Universitario Gregorio Marañón. Hospital Universitari Vall d’Hebron, Vall d’Hebron Barcelona Hospital Campus,

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Predicting pulmonary hypertension in infants with bronchopulmonary dysplasia

Henry P. Foote, Minghui Sun, Benjamin Alan Goldstein, Kevin D. Hill, Rachel G. Greenberg, Samuel J. Gentle, Kanecia O. Zimmerman, Rishikesan Kameleswaran, Veeral N. Tolia, Matthew M. Laughon, Wesley Jackson, Christoph P. HornikDuke University Medical Center and Duke University. Yale University School of Medicine. Baylor University Medical Center. University of North Carolina. United States Journal

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Jinlong Liu, Xiafeng Yu, Jiwen Xiong, Yi Yan, Yanjun Sun, Yumin Zhong, Hao ZhangShanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine.China Frontiers in Bioengineering and BiotechnologyFront Bioeng Biotechnol 2026; 13: DOI: 10.3389/fbioe.2025.1697468 AbstractObjectives: Reverse Potts shunt is a promising yet high-risk therapy for pediatric pulmonary arterial hypertension. Postoperative hemodynamics is critically influenced by

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Deep Learning-Based Prediction of Cardiopulmonary Disease in Retinal Images of Premature Infants

Praveer Singh, Sourav Kumar, Riya Tyagi, Benjamin K. Young, Brian K. Jordan, Brian Scottoline, Patrick D. Evers, Susan Ostmo, Aaron S. Coyner, Wei-Chun Lin, Aarushi Gupta, Deniz Erdogmus, Paul Chan, Emily A. McCourt, James S. Barry, Cindy T. McEvoy, Micheal F. Chiang, Peter Campbell, Jayashree Kalpathy-CramerUniversity of Colorado School of Medicine. Massachusetts General Hospital and

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Construction of an early diagnostic model for pulmonary hypertension based on aging-related signature genes and identification of potential therapeutic targets

MengzeWang, Jiafei Lu, Xinyu Li, Huating Xie, Junjie Liang, Jun Luo, Xishu Deng, Guoquan Pan, Bowen Ji, Xiaojie DingKunming Children’s Hospital. Southern Medical University. Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University. Taizhou Central Hospital (Taizhou University Hospital). Second Hospital of Jiaxing and Second Affiliated Hospital of Jiaxing University. Zhejiang Rongjun Hospital.

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