Genetic Factors Associated With Pulmonary Vascular Disease

Adrenomedullin Overexpression Protects Mice from Experimental Bronchopulmonary Dysplasia and Associated Pulmonary Hypertension

Shyam Thapa, Poonam Sarkar, M. Waleed Gaber, Roberto Barrios, Madhulata Chauhan, Chandrasekhar Yallampalli, Binoy ShivannaTexas Children’s Hospital and Baylor College of Medicine. Houston Methodist HospitalUnited States American Journal of Physiology Lung Cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol Physiol 2025; DOI: 10.1152/ajplung.00234.2025 AbstractBronchopulmonary dysplasia (BPD) associated pulmonary hypertension (PH) or BPD-PH is a lung […]

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Molecular targeted treatment in infants with central conducting lymphatic anomalies

Vera C. van den Brink, Lotte E. R. Kleimeier, Erika K. S. M. Leenders, Willemijn M. Klein, Willem P. de Boode, Joris Fuijkschot, Sabine L. A. G. VranckenAmalia Children’s Hospital, Radboud University Medical Center. Netherlands European Journal of PediatricsEur J Pediatr 2025; 184: DOI: 10.1007/s00431-025-06376-2 AbstractCentral conducting lymphatic anomaly (CCLA) is a rare and potentially life-threatening

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SOX17-silenced HPAECs upregulate NF-κB-induced CXCL10 and CXCL11: implications for lymphocyte chemotaxis in SOX17-PAH

Abdul S. Mahomed, Anne Burke-Gaffney, Shahin Moledina, Quezia K.Toe, Dongmin Shao, Gregory J. Quinlan, Christopher J. Rhodes, James E. Pease, Stephen JohnWortImperial College London. Great Ormond Street Hospital for Children NHS Foundation Trust. Royal Brompton Hospital.United Kingdom Scientific ReportsSci Rep 2025; 15: DOI: 10.1038/s41598-025-16418-2 AbstractPulmonary arterial hypertension (PAH) is a progressive pulmonary vasculopathy characterized by extensive

SOX17-silenced HPAECs upregulate NF-κB-induced CXCL10 and CXCL11: implications for lymphocyte chemotaxis in SOX17-PAH Read More »

Clinico-epidemiological Characteristics of Children with Cystic Fibrosis: a Tertiary Care Experience

Probir K. Sarker, N. Akand, S. Tahura. M. Kamruzzaman, J. Akter, K. A. Zaman, T. Farhana, M. M. Hossain, M. J. Alam, M. A. S. Khan, M. J. HasanBangladesh Shishu Hospital & Institute. Bangladesh Mymensingh Medical Journal Mymensingh Med J 2025; 34: 1070-1080DOI Not Available AbstractTo describe the clinico-epidemiological characteristics of pediatric cystic fibrosis (CF)

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Turner syndrome with pulmonary arteriovenous malformation: a case report

Huibin Guo, Hongqiao Chen, Sihao Chen, Shilong TangUniversity-Town Hospital of Chongqing Medical University. Children’s Hospital of Chongqing Medical University.China Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2025; 12: DOI: 10.3389/fcvm.2025.1603250 AbstractTurner syndrome (TS) is the most common sex chromosome abnormality disorder, caused by complete or partial absence of the X chromosome, its clinical manifestations primarily include short

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The Effect of Microvascular Remodeling on Fluid Dynamics in the Pressure Overloaded Right Ventricle

Ilham Essafri, Kenzo Ichimura, Dunbar Ivy, Kurt R. Stenmark, Helena A. Turton, Laura L. Pyle, Edda Spiekerkoetter, Vitaly O. KheyfetsUniversity of Colorado Anschutz Medical Campus and Children’s Hospital Colorado. Stanford University, Stanford. United States American Journal of Physiology Heart and Circulatory PhysiologyAm J Physiol Heart Circ Physiol 2025; DOI: 10.1152/ajpheart.00147.2025 AbstractRight ventricular (RV) failure, a major

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How Is Pulmonary Hypertension Characterised and Treated in Children With Trisomy 21? Observations From the TOPP Registry (Tracking Outcomes and Practice in Pediatric Pulmonary Hypertension)

Tilman Humpl, Rolf M. F. Berger, Damien Bonnet, Maurice Beghetti, Dunbar Ivy, for the TOPP InvestigatorsDistrict Hospital of Loerrach Germany. Beatrix Children’s Hospital. Hôpital Necker Enfants Malades. Children’s University Hospital. Childrens Hospital Colorado and University of Colorado School of Medicine.Germany, Netherlands, France, Switzterland and United States Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70146 AbstractPulmonary hypertension is

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Surviving trisomy 18: A case report of a 5-year-old girl

Mohamad A. Banat, Ramzi Mujahed, Sama S. Yaseen, Nada A. Makhalfeh, Shahed O. Rajabi, Baraa Abu Aisheh, Rama N. BasheerPalestine Polytechnic University. Princess Alia Governmental Hospital.Palestine MedicineMedicine 2025; 104: DOI: 10.1097/MD.0000000000044225 AbstractRationale: Trisomy 18, often known as Edwards syndrome. It is a common chromosomal disorder characterized by the presence of an extra chromosome 18. Unfortunately, survival past

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Successful Treatment of Severe Hepatopulmonary Syndrome as a Rare Complication of Zellweger Spectrum Disorder

Riya Mary Tharakan, Sanjay Rajwal, Bernd C. SchwahnSt Mary’s Hospital Manchester University NHS Foundation Trust. Leeds Children’s Hospital. Medicine and Health University of Manchester. United Kingdom Journal of Inherited Metabolic Disorders ReportsJIMD Rep 2025; DOI: 10.1002/jmd2.70026 AbstractWe report the case of an 11-year-old girl who developed hepatopulmonary syndrome (HPS) as a rare complication of Zellweger spectrum

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Supravalvular aortic stenosis – Novel pathogenic ELN variant in siblings with a wide spectrum of clinical cardiovascular features and a long follow-up from infancy to adulthood

Sini Keskinen, Jussi Niemelä, Hannele Koillinen, Talvikki Boldt, Anita ArolaTurku University Hospital and University of Turku. New Children’s HospitalFinland Cardiovascular Revascularization MedicineCardiovasc Revasc Med 2025; DOI: 10.1016/j.carrev.2025.04.027 AbstractBackground: Supravalvular aortic stenosis (SVAS) is an autosomal dominantly inherited congenital cardiovascular disease caused by disruption of elastin gene (ELN), encoding elastin, an essential component of elastic arteries. It usually

Supravalvular aortic stenosis – Novel pathogenic ELN variant in siblings with a wide spectrum of clinical cardiovascular features and a long follow-up from infancy to adulthood Read More »

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