Genetic Factors Associated With Pulmonary Vascular Disease

Effect of Estrogen Receptor Alpha on Cardiopulmonary Adaptation to Chronic Developmental Hypoxia in a Rat Model

Nicholas T. Severyn, Patricia Esparza, Huanling Gao, Elizabeth A. Mickler, Marjorie E. Albrecht, Amanda Fisher, Bakhtiyor Yakubov, Todd G. Cook, James E. Slaven, Avram D. Walts, Robert S. Tepper, Tim LahmUniversity of Kentucky. Indiana University – Purdue University Indianapolis. University of Colorado. National Jewish Health.United States American Journal of Physiology Lung Cellular and Respiratory PhysiologyAm […]

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Dynamically stiffening biomaterials reveal age- and sex-specific differences in pulmonary arterial adventitial fibroblast activation

Mikala C. Mueller, Yanmei Du, Lori A. Walker, Chelsea M. MaginUniversity of Colorado, Anschutz Medical Campus.United States Matrix Biology PlusMatrix Biol Plus 2024; DOI: 10.1016/j.mbplus.2024.100145 AbstractRespiratory diseases like pulmonary arterial hypertension (PAH) frequently exhibit sexual dimorphism. Female PAH patients are more susceptible to the disease but have increased survival rates. This phenomenon is known as the

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Deficiency of the Deubiquitinase UCHL1 Attenuates Pulmonary Arterial Hypertension

Haiyang Tang, Akash Gupta, Seth A. Morrisroe, Changlei Bao, Tae-Hwi Schwantes-An, Geetanjali Gupta, Shuxin Liang, Yanan Sun, Aiai Chu, Ang Luo, Venkateswaran Ramamoorthi Elangovan, Shreya Sangam, Yinan Shi, Samisubbu R. Naidu, Jia-Rong Jheng, Sultan Ciftci-Yilmaz, Noel A. Warfel, Louise Hecker, Sumegha Mitra, Anna W. Coleman, Katie A. Lutz, Michael W. Pauciulo, Yen-Chun Lai, Ali Javaheri,

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Early identification of SOX17 deficiency in infants to guide management of heritable pulmonary arterial hypertension using PDA stent to create reverse Potts shunt physiology

Heidi Ostler, Carolyn Fall, Howaida El‐Said, Henri Justino, Shylah Haldeman, Jeanne Carroll, Rohit RaoRady Children’s Hospital and University of California San Diego California.United States Pulmonary CirculationPulm Circ 2024; 14:DOI: 10.1002/pul2.12366 AbstractHeritable pulmonary arterial hypertension (HPAH) is a rare progressive condition that includes patients with an identified genetic cause of pulmonary arterial hypertension (PAH). HPAH and idiopathic

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The Outcome of Congenital Cardiac Surgery in Patients with Down Syndrome: Single-Center Experience

Abdulhameed A. Alnajjar, Sherif S. Salem, Luna S. Baangood, Mansour B. Al-Mutairi, Mohamed F. Morsy, Mustafa Al-Muhaya, Alassal A. Alkodami, Merhamer L. Sabtirul, Mohamed S. Hussein, Eman W. Altommeihi, Ahmed M. Shaban, Mohamed Alashwal, Ayman R. AbdelrehimMadinah Cardiac Center. Menoufia University. Sohag University. Suez Canal University. Saudi Arabia and Egypt Heart Surgery ForumHeart Surg Forum

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Case report: Blotchy skin in a puffy neonate: is there a new association?

Chacko J. Joseph, Arijit Lodha, Soumya R. Thomas, Essa Al Awad, Nicola A. M. Wright, Cora Constantinescu, Doan Le, Majeeda KamaluddeenUniversity of Calgary Cumming School of Medicine. University of Alberta. Canada Frontiers in PediatricsFront Pediatr 2023; 11:DOI: 10.3389/fped.2023.1247343 AbstractIntroduction: Purpura fulminans in the neonatal population is a rare but potentially life-threatening condition complicated by thrombosis, resultant vital

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Chylothorax related to acute SARS-CoV-2 infection in a patient with Noonan syndrome with prior uncomplicated cardiac surgeries

Lubaina Ehsan, Jessica A. Thoe, John J. Parent, Joseph D. FakhouryWestern Michigan University Homer Stryker M.D, School of Medicine and Bronson Children’s Hospital. Indiana University School of Medicine.United States Cardiology in the YoungCardiol Young 2024; 34: 448-451DOI: 10.1017/S1047951123004171 AbstractSARS-CoV-2 is a novel coronavirus that has rarely been associated with chylothorax. Patients with Noonan syndrome are at

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PKD1L1 Is Involved in Congenital Chylothorax

Jonathan B. Whitchurch, Sophia Schneider, Alina C. Hilger, Ricarda Köllges, Jil D. Stegmann, Lea Waffenschmidt, Laura Dyer, Holger Thiele, Bhanupriya Dhabhai, Tikam Chand Dakal, Andreas Müller, Dominic P. Norris, Heiko M. ReutterHarwell Campus. University Hospital Bonn. University Hospital Erlangen. University of Cologne. Mohanlal Sukhadia University.United Kingdom, Germany and India CellsCells 2024; 13:DOI: 10.3390/cells13020149 AbstractBesides visceral heterotaxia, Pkd1l1 null

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Causal association of depression, anxiety, cognitive performance, the brain cortical structure with pulmonary arterial hypertension: A Mendelian randomization study

Zeying Zhang, Shelby Kutty, Wei Peng, Gaoming Zeng, Haiyan Luo, Zhenghui Xiao, Qiming Liu, Yunbin XiaoSecond Xiangya Hospital of Central South University. Johns Hopkins School of Medicine. Hunan Children’s Hospital. China Journal of Affective DisordersJ Affect Dis 2024;DOI: 10.1016/j.jad.2024.01.276 AbstractBackground: Patients with pulmonary arterial hypertension (PAH) often present with anxiety, depression and cognitive deterioration. Structural changes in

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The First Korean Case with Cardiac, Facial, and Digital Anomalies with Developmental Delay Caused by De Novo TRAF7 p.Arg655Gln Variant

Kyung Hee Kim, Ji Yoon Han, Joonhong Park, Jung Sun ChoThe Catholic University of Korea. Jeonbuk National University Medical School and Hospital. Republic of Korea International Journal of Molecular SciencesInt J Mol Sci 2024; 25:DOI: 10.3390/ijms25073701 AbstractTRAF7-related disorders represent some of the rarest inherited disorders, exhibiting clinical features that overlap with cardiac, facial, and digital anomalies

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