Fresh (PHresh). Less than 1-2 years since publication

Case Report: Tracheobronchomalacia after a two-stage surgical approach to treat congenital diaphragmatic hernia with hepatopulmonary fusion

Juri Kanda, Takeo Mukai, Chiharu Irisa, Kyosuke Ibi, Rina Matsuda, Kaori Morita, Akio Ishiguro, Masako Ikemura, Yosuke Yamada, Hisaya Hasegawa, Jun Fujishiro, Naoto TakahashiUniversity of Tokyo Hospital. Tokyo Women’s Medical University Adachi Medical Center.Japan Frontiers in PediatricsFront Pediatr 2025; 13: DOI: 10.3389/fped.2025.1573827 AbstractHepatopulmonary fusion (HPF) is a rare comorbidity of right-sided congenital diaphragmatic hernia (CDH). The

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Targeted Therapy for Complex Lymphatic Anomalies in Patients with Noonan Syndrome and Related Disorders

Erika K. S. M. Leenders, Vera C. van den Brink, Lotte E. R. Kleimeier, Danielle T. J. Woutersen, Catelijne H. Coppens, Jeroen den Hertog, Willemijn M. Klein, Tuula Rinne, Sabine L. Vrancken, Saskia N. de Wildt, Jos M. T. Draaisma, Joris FuijkschotRadboud University Medical Center and Amalia Children’s Hospital. University Medical Center Utrecht. Leiden University.

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Targeted Proteomic Analysis of Sickle Cell Disease Patients With Elevated Tricuspid Regurgitation Velocity

Varshini Babu, Jane A. Little, Claudia R. Morris, Roberto Machado, Simon Gibbs, Gregory A. Kato, Victor R. Gordeuk, MArk T. Gladwin, Yingze Zhang, Seyed Mehdi NouraieUniversity of Pittsburgh. University of North Carolina at Chapel Hill.  Emory University School of Medicine and Children’s Healthcare of Atlanta. Indiana University. Imperial College London. CSL Behring. University of Illinois

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Cardiovascular disease in Sickle cell: mechanisms, diagnostics and therapeutic advances

Elio Haroun, Ankit Agrawal, Aro Daniela Arockiam, Joseph El Dahdah, Joseph Kassab, Michael Nakhla, Michel Chedid El Helou, Harsha Sanaka, Ziad Zalaquett, Simrat Kaur, Tiffany Dong, Rabi Hanna, Brian Griffin, Tom Kai Ming WangCleveland Clinic. United States HeartHeart 2025; DOI: 10.1136/heartjnl-2025-325837 AbstractCardiovascular complications are increasingly recognised as a major driver of morbidity and early mortality in patients

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Echocardiographic assessment of pediatric lupus nephritis and its correlation with disease activity in a tertiary care hospital

Afroza Begum, Amina Akter, Nadira Sultana, Abdullah Al Mamun, Tahmina Jesmin, Syed Saimul Huque, Shanjida Sharmim, Sharmim Akter Luna, Shamsunnahar Shanta, Samina Masud Santa, Sabina Sultana, Ranjit RoyBangabandhu Sheikh Mujib Medical University. Gonoshasthaya Samaj Vittik Medical College. Evercare Hospital.Bangladesh LupusLupus 2025; DOI: 10.1177/09612033251367175 AbstractSystemic lupus erythematosus (SLE) is a complex autoimmune disease with multisystem involvement. Lupus

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Pharmacological Treatment Practices for Patients with Congenital Heart Disease and Pulmonary Hypertension in Japan: Insights from the Japanese Association of Congenital Heart Disease Registry (JACPHR)

Taku Ishii, Keiko Uchida, Susumu Hosokawa, Reina Ishizaki, Naofumi F. Sumitomo, Yoshiyuki Furutani, Hidekazu Ishida, Shinichi Takatsuki, Kei Inai, Kunihiko Takahashi, Shigetoyo Kogaki, Hiroyuki Fukushima, Yuichi Tamura, Hiroyuki Yamagishi, Shozaburo Doi, Japanese Association of Congenital Heart Disease Registry (JACHDR) membersInstitute of Science Tokyo. Keio University School of Medicine, Tokyo Medical University. Japanese Red Cross Mushashino

Pharmacological Treatment Practices for Patients with Congenital Heart Disease and Pulmonary Hypertension in Japan: Insights from the Japanese Association of Congenital Heart Disease Registry (JACPHR) Read More »

Shone’s Syndrome and Transplant: A Road Less Traveled

Lyana Labrada, Tripti Gupta, Christiane Haeffele, Adam D. DeVore, Jonathan MenachemTemple University Hospital. University of San Diego. Stanford University. Duke University School of Medicine. Vanderbilt University Medical Center.United States Journal of the American College of Cardiology Case ReportsJACC Case Rep 2025; DOI: 10.1016/j.jaccas.2025.105000 Abstract“Shone’s syndrome” was identified in 1963 as a constellation of 4 coexisting lesions

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Inpatient outcomes among children with Down syndrome: a Kids’ Inpatient Database study

Po-Yang Tsou, Yu-Hsun Wang, Ignacio E. TapiaBoston Children’s Hospital and Harvard Medical School. Tufts Medical Center. University of Miami Health System.United States BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-05899-9 AbstractBackground: Children with Down Syndrome (DS) are more likely to have multi-system comorbidities leading to more frequent hospitalizations than the general population. We aim to evaluate whether

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p53 maintains lineage fidelity during lung capillary injury-repair in neonatal hyperoxia

Lisandra Vila Ellis, Jonathan D. Bywaters, Amanda Ceas, Yun Liu, Jennifer M. S. Sucre, Jichao ChenNorthwestern University.  Vanderbilt University Medical Center. Cincinnati Children’s Hospital Medical Center.United States Journal of Clinical Investigation InsightsJCI Insights 2025;DOI: 10.1172/jci.insight.182880 AbstractBronchopulmonary dysplasia (BPD), a prevalent and chronic lung disease affecting premature newborns, results in vascular rarefaction and alveolar simplification. Although the

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Hereditary hemorrhagic telangiectasia in pediatrics: descriptive study in a specialized unit

Magalí Squitín Tasende, Nicolás Guerrero Serravalle, Lucía G. Pérez, Ana Braslavsky, Marcelo SerraHospital Italiano de Buenos Aires and Universidad Hospital Italiano.Argentina Archivos Argentinos de PediatríaArch Argent Pediatr 2025; DOI: 10.5546/aap.2025-10661.eng AbstractIntroduction. Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular dysplasia characterized by bleeding telangiectasias and arteriovenous malformations (AVMs) in the brain, lungs, liver, and gastrointestinal

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