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Single-Cell and Spatial Transcriptomics Identified Fatty Acid-Binding Proteins Controlling Endothelial Glycolytic and Arterial Programming in Pulmonary Hypertension

Bin Liu, Dan Yi, Shuai Li, Karina Ramirez, Xiaomei Xia, Yanhong Cao, Hanqiu Zhao, Ankit Tripathi, Shenfeng Qiu, Mrinalini Kala, Ruslan Rafikov, Haiwei Gu, Vinicio de jesus Perez, Sarah-Eve Lemay, Christopher C. Glembotski, Kenneth S. Knox, Sebastien Bonnet, Vladimir V. Kalinichenko, You-Yang Zhao, Michael B. Fallon, Olivier Boucherat, Zhiyu DaiCollege of Medicine-Phoenix and University of Arizona. Washington University School of Medicine in St. Louis. Guangzhou Medical University. Indiana University College of Medicine. Arizona State University. Stanford University. Laval University. Phoenix Children’s Hospital. Ann & Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg School of Medicine.United […]

Single-Cell and Spatial Transcriptomics Identified Fatty Acid-Binding Proteins Controlling Endothelial Glycolytic and Arterial Programming in Pulmonary Hypertension Read More »

Reverse Potts shunt as rescue from venoarterial extracorporeal membrane oxygenation in pulmonary veno-occlusive disease

Emily Davis, Can Yerebakan, John T. BergerUMC Children’s Hospital and University Medical Center of Southern Nevada. Nationwide Children’s Hospital. Children’s National Hospital.United States Cardiology in the YoungCardiol Young 2025; DOI: 10.1017/S1047951125001957 AbstractPulmonary veno-occlusive disease has no definitive cure apart from lung transplant. The reverse Potts shunt can be a palliative bridge to transplant. A post-arrest 14-year-old

Reverse Potts shunt as rescue from venoarterial extracorporeal membrane oxygenation in pulmonary veno-occlusive disease Read More »

Evaluating the relevance of the 2024 BSR systemic sclerosis guideline to juvenile systemic sclerosis

Clare E. Pain, Hanna Lythgoe, Emily Willins, Sunil Sampath, Samundeeswari Deepak, Kathryn S. Torok, Phuoc H. Duong, Shahin Moledina, Juliana Silva, Clarissa Pilkington, Eslam Al-Abadi, Christopher P. DentonAlder Hey Children’s Hospital. Royal Manchester Children’s Hospital. Great North Children’s Hospital. Nottingham Children’s Hospital. UPMC Children’s Hospital of Pittsburgh. Birmingham Women’s and Children’s Hospital. University College London.

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Group D of pulmonary arterial hypertension and its relationship to congenital heart disease: Is there a non-invasive way to predict the unpredictable?

Antoine Fakhry AbdelMassih, Alyaa AlAli, Emad Nasr, Eman Hanafy, Musaab RamsiCairo University. heikh Khalifa Medical City and Pure Health Group. Aswan Heart Centre. Helwan University. Egypt and United Arab Emirates Global Cardiology Science and PracticeGlob Cardiol Sci Pract 2025; DOI: 10.21542/gcsp.2025.5 AbstractPulmonary arterial hypertension related to congenital heart disease (PAH-CHD), can pose a few challenging therapeutic

Group D of pulmonary arterial hypertension and its relationship to congenital heart disease: Is there a non-invasive way to predict the unpredictable? Read More »

Evaluation of Exome and Genome Sequencing for Critically Ill Pediatric Cardiac Patients

Angela C. Onorato, Rachel Gosselin, Bimal P. Chaudhari, Chance Alvarado, Peter White, Vidu Garg, Amee M. BigelowNationwide Children’s Hospital.United States Research SquareRes Sq 2025; DOI: 10.21203/rs.3.rs-6314694/v1 AbstractGenetic testing guidelines for children in cardiac intensive care units (CICUs) are lacking despite a high prevalence of genetic diseases among this population. Advances in next-generation sequencing (NGS) technologies, especially

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Postrepair Pulmonary Vein Stenosis: Addressing Anatomic and Patient Risk Factors to Improve Outcomes

Alessia Di Nardo, Elizabeth D. Persaud, Rachel D. VanderlaanUniversity of Toronto and Hospital for Sick Children.Canada Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery AnnualSemin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2025; 28: 107-116DOI: 10.1053/j.pcsu.2025.02.008 AbstractSurgical results for correction of total anomalous pulmonary venous connection (TAPVC) have improved in the current era. Postrepair pulmonary

Postrepair Pulmonary Vein Stenosis: Addressing Anatomic and Patient Risk Factors to Improve Outcomes Read More »

USP11 Promotes Endothelial Apoptosis-Resistance in Pulmonary Arterial Hypertension by Deubiquitinating HINT3

Bum-Yong Kang, Jiwoong Choi, Victor Tseng, Yutong Zhao, Jing Zhao, Robert S. Stearman, Wilbur A. Lam, Viranuj Sueblinvong, Benjamin T. Kopp, Michael J. Passineau, Changwon Park, John Lister, Raymond J. Benza, Andrew J. JangEmory University School of Medicine. Atlanta Veterans Healthcare System. University of Kansas School of Medicine and University of Kansas. Ansible Health. Ohio

USP11 Promotes Endothelial Apoptosis-Resistance in Pulmonary Arterial Hypertension by Deubiquitinating HINT3 Read More »

Burden of pulmonary arterial hypertension in Asia from 1990 to 2021: Findings from Global Burden of Disease Study 2021

Shenshen Huang, Jiayong Qiu, Anyi Wang, Yuejiao Ma, Peiwen Wang, Dong Ding, Luhong Qiu, Shuangping Li, Mengyi Liu, Jiexin Zhang, Yimin Mao, Yi Yan, Xiqi Xu, Zhicheng JingFirst Affiliated Hospital and College of Clinical Medicine of Henan University of Science and Technology. Second Hospital of Hebei Medical University. Peking Union Medical College Hospital, Chinese Academy

Burden of pulmonary arterial hypertension in Asia from 1990 to 2021: Findings from Global Burden of Disease Study 2021 Read More »

Pulmonary artery-targeted low-dose metformin-loaded nanocapsules safely improve pulmonary arterial hypertension in rats

Ayako Chida-Nagai, Naoki Masaki, Hiroki Sato, Tatsuya Kato, Emi Takakuwa, Yoshihiro Matsuno, Atsushi Manabe, Atsuhito TakedaHokkaido University Hospital. Tokyo Women’s Medical University. Tohoku University Graduate School of Medicine. Oita University and Oita University Hospital.Japan Frontiers in PediatricsFront Pediatr 2025; 16: DOI: 10.3389/fphar.2025.1577570 AbstractIntroduction: Pulmonary arterial hypertension (PAH) remains a challenge to tackle despite various available medications. Metformin,

Pulmonary artery-targeted low-dose metformin-loaded nanocapsules safely improve pulmonary arterial hypertension in rats Read More »

Risk factors for severe pertussis in children and the application of exchange transfusion

Qihong Chen, Lihua Lin, Shuping Xiong, DandanGe, Yungang YangFirst Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University. Pediatric Key Laboratory of Xiamen. Pediatric Quality Control Center of Xiamen. China Pediatric ResearchPediatr Res 2025; DOI: 10.1038/s41390-025-04118-6 AbstractObjective: To identify risk factors for severe pertussis and assess the efficacy of exchange transfusion in children.Methods: We analyzed pediatric pertussis

Risk factors for severe pertussis in children and the application of exchange transfusion Read More »

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