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Longitudinal follow-up of mixed connective tissue disease and overlapping autoimmune diseases of childhood onset in the Afro-descendant population of the French West Indies

Arthur Felix, Lindsay Osei, Frederique Delion, Benoit Suzon, Aurore Abel, Moustapha Drame, Yves Hatchuel, Christophe Deligny, Fabienne Louis‑SidneyUniversity of the French West Indies and Martinique University Hospital. CHU de la Martinique La Meynard. Andrée Rosemon Hospital. Guadeloupe University Hospital. France Pediatric Rheumatology Online JournalPediatr Rheumatol Online J 2024; 22:DOI: 10.1186/s12969-023-00951-3 AbstractIntroduction: Overlap autoimmune syndromes (OAS) and mixed […]

Longitudinal follow-up of mixed connective tissue disease and overlapping autoimmune diseases of childhood onset in the Afro-descendant population of the French West Indies Read More »

Vasopressin in newborns with refractory acute pulmonary hypertension

Simon Ouellet, Christine Drolet, Genevéve Morissette, Annie Pellerin, Audrey HébertCHU de Québec, Université Laval. Canada Pediatric ResearchPediatr Res 2024;DOI: 10.1038/s41390-023-02995-3 AbstractBackground: Acute pulmonary hypertension (aPH) in newborns can be life threatening and challenging to manage. In newborns with refractory aPH, there is currently limited therapeutic agents.Methods: Retrospective single-center cohort study in newborns less than one month old who

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Fetal MRI-Based Mediastinal Shift Angle (MSA) and Percentage Area of Left Ventricle (pALV) as Prognostic Parameters for Congenital Diaphragmatic Hernia

Greta Thater, Lara Angermann, Silviu-Viorel Virlan, Christel Weiss, Neysan Rafat, Michael Boettcher, Julia Elrod, Tom Bayer, Oliver Nowak, Stefan O. Schönberg, Meike WeisUniversity Medical Center Mannheim. Hospital Stuttgart. Germany Journal of Clinical MedicineJ Clin Med 2024; 13:DOI: 10.3390/jcm13010268 AbstractObjective: Fetal magnetic resonance imaging (MRI) is broadly used as a method for assessing prognosis in congenital diaphragmatic hernia

Fetal MRI-Based Mediastinal Shift Angle (MSA) and Percentage Area of Left Ventricle (pALV) as Prognostic Parameters for Congenital Diaphragmatic Hernia Read More »

Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension

Yi- Yin Tai, Qiujun Yu, Ying Tang, Wei Sun, Neil J. Kelly, Satoshi Okawa, Jingsi Zhao, Tae- Hwi Schwantes-An, Caroline Lacoux, Stephanie Torrino, Yassmin Al Aaraj, Wadih El Khoury, Vinny Negi, Mingjun Liu, Catherine G. Corey, Frances Belmonte, Sara O. Vargas, Brian Schwartz, Bal Bhat, B. Nelson Chau, Jason H. Karnes, Taijyu Satoh, Robert J.

Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension Read More »

Prognostic and diagnostic utility of interleukin-6 in pediatric pulmonary arterial hypertension – a case-control study

Mohamed Abdallah Abd El Megied, Mohammed Ahmed Abouelhassan, Eman Saad Abd El Salam HadwaCairo University.Egypt European Journal of PediatricsEur J Pediatr 2024;DOI: 10.1007/s00431-023-05413-2 AbstractPulmonary arterial hypertension (PAH) in pediatrics is a progressive disease with significant vascular remodeling, right sided heart failure, and death if left untreated. Elevated interleukin-6 (IL-6) level in PAH patients is taken as

Prognostic and diagnostic utility of interleukin-6 in pediatric pulmonary arterial hypertension – a case-control study Read More »

Computed tomographic findings in TBX4 mutation: a common cause of severe pulmonary artery hypertension in children

Helio V. Neves da Silva, Jason P. Weinman, Erin K. Englund, Robin R. Deterding, D. Dunbar Ivy, Lorna P. BrowneChildren’s Hospital Colorado and University of Colorado School of Medicine, Anschutz Medical Campus. Highland Hospital. United States Pediatric RadiologyPediatr Radiol 2024;DOI: 10.1007/s00247-023-05848-7 AbstractBackground: Mutations in the T-Box 4 (TBX4) gene are a lesser-known cause of heritable pulmonary arterial

Computed tomographic findings in TBX4 mutation: a common cause of severe pulmonary artery hypertension in children Read More »

Blood DNA methylation profiling identifies cathepsin Z dysregulation in pulmonary arterial hypertension

Anna Ulrich, Yukyee Wu, Harmen Draisma, John Wharton, Emilia M. Swietlik, Inês Cebola, Eleni Vasilaki, Zhanna Balkhiyarova, Marjo-Riitta Jarvelin, Juha Auvinen, Karl-Heinz Herzig, J. Gerry Coghlan, James Lordan, Colin Church, Luke S. Howard, Joanna Pepke-Zaba, Mark Toshner, Stephen J. Wort, David G. Kiely, Robin Condliffe, Allan Lawrie, Stefan Gräf, Nicholas W. Morrell, Martin R. Wilkins,

Blood DNA methylation profiling identifies cathepsin Z dysregulation in pulmonary arterial hypertension Read More »

Pulmonary Artery Hypertension in Transfusion-Dependent Thalassemia

Vineeta Gupta, Vishnu Vijayakumar, Priyanka Aggarwal Ishan Kumar, Vikas AgrawalBanaras Hindu University. India Indian PediatricsIndian Pediatr 2024; 61: 49-52DOI: Not Available AbstractObjective: Patients with transfusion-dependent thalassemia (TDT) are at risk of developing pulmonary artery hypertension (PAH) due to chronic hemolysis, iron overload, hypercoagulability and splenectomy. The objective of the study was to assess the prevalence and

Pulmonary Artery Hypertension in Transfusion-Dependent Thalassemia Read More »

Utility of Balloon Occlusion Testing in Determining Fontan Suitability Among Patients with Elevated Pulmonary Artery Pressure and Additional Antegrade Pulmonary Blood Flow

Ibrahim Halil Demir, Ahmet Celebi, Dursun Muhammed Ozdemir, Emine Hekim Yilmaz, Mustafa Orhan Bulut, Murat Surucu, Oktay Korun, Numan Ali Aydemir, Ilker Kemal YucelUniversity of Health Sciences Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital. Istanbul University. Turkey Pediatric CardiologyPediatr Cardiol 2024;DOI: 10.1007/s00246-023-03380-x AbstractIn individuals with a single ventricle undergoing evaluation before Fontan

Utility of Balloon Occlusion Testing in Determining Fontan Suitability Among Patients with Elevated Pulmonary Artery Pressure and Additional Antegrade Pulmonary Blood Flow Read More »

Tumor Necrosis Factor-α-Induced Protein-8-like 2 Transfected Adipose-Derived Stem Cells Regulated the Dysfunction of Monocrotaline Pyrrole-Induced Pulmonary Arterial Smooth Muscle Cells and Pulmonary Arterial Endothelial Cells

Jing Li, Xin He, Feng Liu, Kinglong Zheng, Jing JiangFirst Affiliated Hospital of Xi’an Jiaotong University. Fourth Military Medical University.China Journal of Cardiovascular PharmacologyJ Cardiovasc Pharmacol 2024; 83:73-85DOI: 10.1097/FJC.0000000000001505 AbstractPulmonary arterial hypertension (PAH) is characterized by pulmonary arterial endothelial cell (PAEC) dysfunction and pulmonary arterial smooth muscle cell (PASMC) activation. For decades, the therapies for PAH

Tumor Necrosis Factor-α-Induced Protein-8-like 2 Transfected Adipose-Derived Stem Cells Regulated the Dysfunction of Monocrotaline Pyrrole-Induced Pulmonary Arterial Smooth Muscle Cells and Pulmonary Arterial Endothelial Cells Read More »

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