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Management strategy for congenital hyperinsulinism with atrial septal defect and diazoxide-induced pulmonary hypertension

Sayuri Koizumi, Ikuma Musha, Koichi Toda, Hiroshi Kawana, Chikahiko Numakura, Katsuhiko Tabata, Takamasa Mizumoto, Taisuke Nabeshima, Takuro Kojima, Toshiki Kobayashi, Takaya Hoashi, Toru KikuchiSaitama Medical University Hospital. Japan Clinical Pediatric EndocrinologyClin Pediatr Endocrinol 2025; 34: 188-192DOI: 10.1297/cpe.2024-0096 AbstractCongenital hyperinsulinism (CHI) is characterized by hypoglycemia caused by excessive insulin secretion. CHI is classified into two types: transient […]

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Stereotactic body radiotherapy: a new non-invasive way to conduct pulmonary artery denervation

Manzhen Liao, Taoyue Yao, Yonghui Xie, Shelby Kutty, Jinqiao Liu, Wei Peng, Ting Huang, Huaiyang Chen, Haoqin Fan, Zhenghui Xiao, Qiming Liu, Yunbin XiaoAffiliated Nanhua Hospital and University of South China. Affiliated Children’s Hospital of Xiangya School of Medicine and Central South University (Hunan Children’s Hospital). Johns Hopkins School of Medicine. China and Uhited States

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Comparison of the oxygenation index and the oxygen saturation index as clinical indicators for neonatal ECMO

John Slaughter, Jeremy Sites, Hubert Ballard, John Bauer, Aric Schadler, Nicholas SeverynUniversity of Kentucky College of Medicine. United States Frontiers in PediatricsFront Pediatr 2025; 13: DOI: 10.3389/fped.2025.1586985 AbstractIntroduction: Neonatal hypoxic respiratory failure is commonly assessed with the oxygenation index (OI) to determine severity and guide ECMO initiation. Calculation of the OI requires arterial blood sampling which can

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Cardiovascular protective properties of the natural product eugenol

Xin-yu Liu, Yun-ke Nie, Yang Liu, Mei ChenClinical College of Qilu Medical University. China European Journal of PharmacologyEur J Pharmacol 2025;DOI: 10.1016/j.ejphar.2025.177929 AbstractMedicinal herbs have long been used in traditional medicine and their multi-featured bioactivities against the pathophysiology of chronic diseases are currently being extensively investigated in both experimental and clinical settings. Eugenol, a versatile small

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Prostacyclin Therapy as Adjunctive Treatment for Pulmonary Hypertension in Pediatric Heart Transplantation: A Case Report

Anusha Konduri, Aly J. Sonnen, Heang M. Lim, Kurt R. Schumacher, David M. Peng, Vikram Sood, Mary K. Olive, Amanda D. McCormickUniversity of Michigan.United States Pediatric TransplantationPediatr Transplant 2025; 29: DOI: 10.1111/petr.70129 AbstractBackground: Elevated pulmonary vascular resistance is a significant risk factor for right-ventricle failure and poor outcomes following pediatric heart transplantation. Pulmonary vasodilator therapy can help

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Macitentan in Children with Pulmonary Arterial Hypertension: A Multicenter Experience

A. Rodriguez Ogando, A. Sabaté-Rotés, A. Moya Bonora, L. Albert de la Torre, J. M. Espín López, C. Labrandero de Lera, Maria Jesus Del Cerro MarinGregorio Marañon General University Hospital. Hospital Materno Infantil Gregorio Marañon. Vall d’Hebron University Hospital. La Fe University Hospital. 12 de Octubre University Hospital. Virgen dee la Arrixaca University Hospital. La

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Cardiorespiratory transition in CDH

Deepika Sankaran. Satyan Lakshminrusimha, Michelle J. LimUniversity of California, Davis.United States Seminars in Fetan and Neonatal MedicineSemin Fetal Neonatal Med 2025; DOI: 10.1016/j.siny.2025.101649 AbstractCongenital diaphragmatic hernia (CDH) is a rare congenital anomaly that occurs due to incomplete closure of the diaphragm followed by herniation of abdominal contents into the chest. Fetal hemodynamics are altered in CDH

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Side Cell Dilation of Jailed Pulmonary Veins After Stenting Improves Vessel Preservation in Pediatric Pulmonary Vein Stenosis

Conor P. O’Halloran, Amanda Hauck, Jeremy Fox, Christina Laternser, Emily Hoyt, Alan W. Nugent, Paul TannousAnn & Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg School of Medicine. United States Catheterization and Cardiovascular InterventionsCatheter Cardiovasc Interv2025; DOI: 10.1002/ccd.31737 AbstractIntroduction: Endovascular stent placement for pulmonary vein stenosis (PVS) provides effective obstruction relief. Due to small

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Critical Care Dilemma: Complex Congenital Pulmonary Airway Malformation With Pulmonary Hypertension in a Neonate

Sajjad M. AlKadhem, Ali T. Alattas, Hadeel AlJubab, Abdulwahhab S. AlJubabKing Fahad Medical City.Saudi Arabia CureusCureus 2025; 17: DOI: 10.7759/cureus.85279 AbstractCongenital pulmonary airway malformations (CPAMs) are the most prevalent congenital lung lesions, yet their postnatal trajectory remains heterogeneous. Although many antenatally detected macrocystic lesions remain clinically silent, rapid postnatal enlargement can precipitate tension physiology, air-leak syndromes,

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Proteomic characterization of type I collagen N-terminal crosslinked peptides

Zsuzsanna Darula, Maxwell C. McCabe, Alex Barrett, Lauren R. Schmitt, Mark D. Maslanka, Anthony J Saviola, Joseph Orgel, Alma Burlingame, Claudia A. Staab-Weijnitz, Kurt Stenmark, Valerie Weaver, Robert J. Chalkley, Kirk C. HansenHungarian Centre of Excellence for Molecular Medicine. HUN-REN Biological Research Centre. University of Colorado Denver, Anschutz Medical Campus. Illinois Institute of Technology. University

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