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Giant Omphalocele: Systematic Review of Pulmonary Complications and Implications for Neonatal Care

Joana Peixoto, Joana Neto, Susana Pissarra, Inês Azevedo, Henrique Soares, Gustavo RochaUniversidade do Porto. Centro Hospitalar Universitário de São João. Portugal European Journal of Pediatric SurgeryEur J Pediatr Surg 2025; DOI: 10.1055/a-2649-0781 AbstractThe primary objectives were to know the prevalences of pulmonary hypoplasia (PH), persistent pulmonary hypertension of the newborn (PPHN), and mortality in newborn infants […]

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Enhancing Drug Development for Paediatric Pulmonary Hypertension-An Integrative Perspective

Steven H. Abman, Sylvia M. Nikkho, Rolf M. F. Berger, Maria Jesus del Cerro, Eric D. Austin, Maurice Beghetti, Dunbar Ivy, Megan Griffiths, Anne Hilgendorff, Steven H. Kawut, Usha S. Krishnan, Mary P. Mullen, Shahin Moledina, Bernard Thébaud, Norman StockbridgeUniversity of Colorado School of Medicine and Children’s Hospital Colorado. Bayer AG. Beatrix Children’s Hospital, University

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Long noncoding RNA FGD5-AS1-encoded micropeptides improve right heart functions of pulmonary arterial hypertension through restricting the synthesis of hyaluronic acid

Yijun Chen, Qianhui Zhang, Xi Chen, Yahe Xu, Jing Guo, Jiajia Meng, Mingjie Zhang, Bo Wang, Zhuoming XuShanghai Children’s Medical Center and Shanghai Jiao Tong University School of Medicine.China International Journal of Biological MacromoleculesInt J Biol Macromol 2025; DOI: 10.1016/j.ijbiomac.2025.146018 AbstractPulmonary arterial hypertension (PAH) is marked by elevated vascular resistance, right ventricular (RV) failure, and poor

Long noncoding RNA FGD5-AS1-encoded micropeptides improve right heart functions of pulmonary arterial hypertension through restricting the synthesis of hyaluronic acid Read More »

Utility of patient-reported outcomes for pulmonary symptoms and sleep disturbance and impairment in children with systemic juvenile idiopathic arthritis

Kim Nguyen, Shima Yasin, Ndate Fall, Alexei A. Grom, Hermine I. Brunner, Christopher Towe, Grant S. SchulertTriHealth Hospital System. University of Cincinnati College of Medicine and Cincinnati Children’s Hospital Medical Center.United States Pediatric Rheumatology Online JournalPediatr Rheumatol Online J 2025; 23: DOI: 10.1186/s12969-025-01126-y AbstractBackground: Patient-reported outcomes (PROs) are critical assessment tools for clinical practice, observational studies, and

Utility of patient-reported outcomes for pulmonary symptoms and sleep disturbance and impairment in children with systemic juvenile idiopathic arthritis Read More »

QT dispersion and T wave peak-to-end in pediatric patients with sickle cell disease

Hanaa H. Eldash, Rana Mostafa, Heba A. BorayekFayoum University.Egypt Journal of ElectrocardiologyJ Electrocardiol 2025; DOI: 10.1016/j.jelectrocard.2025.154059 AbstractAim: The aim of the study was to detect cardiac repolarization changes and the risk of arrhythmias in children with sickle cell disease (SCD) and sickle thalassemia using echocardiography and electrocardiography (ECG).Methods: This is an observational case-control study that compared 20 patients

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Genetic features of alveolar capillary dysplasia with misalignment of pulmonary veins in Japanese infants

Masahiko Ikeda, Kazutoshi Cho, Yuta Furuse, Tetsuo Onda, Akiko Ando, Yuichi Nakamura, Yosuke Kaneshi, Atsushi ManabeHokkaido University Hospital. Japan Community Healthcare Organization Hokkaido Hospital. Hokkaido University.Japan Early Human DevelopmentEarly Hum Dev 2025; DOI: 10.1016/j.earlhumdev.2025.106287 AbstractBackground: The genetic features of alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV) among infants in Japan have not been extensively evaluated.Methods: This

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Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990-2021): results from the global burden of disease study

Lili Deng, Jingxuan Xiong, Jiaoli Xu, Qinhong Li, Zugen ChengKunming Children’s Hospital. First Affiliated Hospital of Kunming Medical University. China Frontiers in PediatricsFront Pediatr 2025; DOI: 10.3389/fped.2025.1527281 AbstractIntroduction: Pediatric pulmonary arterial hypertension (PAH) is a rare and severe disorder characterized by obstructive vascular changes that can lead to right heart failure. The clinical presentation and underlying causes

Burden of pulmonary arterial hypertension in children globally, regionally, and nationally (1990-2021): results from the global burden of disease study Read More »

Adaptation of ACMG/AMP Guidelines for Clinical Classification of BMPR2 Variants in Pulmonary Arterial Hypertension Resolves Variants of Unclear Pathogenicity in ClinVar

Christina A. Eichstaedt, Gabriel Maldonado-Velez, Rajiv D. Machado, Stefan Gräf, Dennis Dooijes, Srimmitha Balachandar, Florence Coulet,Kristina Day, Melanie Eyries, Daniela Macaya, Memoona Shaukat, Laura Southgate, Jair Tenorio-Castano, Wendy K. Chung, Carrie L. Welch, Micheala A. AldredThoraxklinik-Heidelberg gGmbH, Heidelberg University Hospital and Translational Lung Research Center (TLRC), German Center for Lung Research (DZL).  Indiana University School

Adaptation of ACMG/AMP Guidelines for Clinical Classification of BMPR2 Variants in Pulmonary Arterial Hypertension Resolves Variants of Unclear Pathogenicity in ClinVar Read More »

Initial Survival and Short-term Pulmonary Comorbidities in Infants with Congenital Diaphragmatic Hernia of Differing Indices of Social Determinants of Health

Yeu Sanz Wu, Alysala Malik, Chunhui Wang, Christian Welch, Caitlin J. Cain-Trivette, Christopher Nemeh, Nicholas Schmoke, Paul Kurlansky, Usha S. Krishnan, Avila De, Vincent Duron Columbia University Irving Medical Center/NewYork Presbyterian Morgan Stanley Children’s Hospital and Columbia University Vagelos College of Physicians & Surgeons. United States Journal of Pediatric SurgeryJ Pediatr Surg 2025; DOI: 10.1016/j.jpedsurg.2025.162460 AbstractPurpose: To

Initial Survival and Short-term Pulmonary Comorbidities in Infants with Congenital Diaphragmatic Hernia of Differing Indices of Social Determinants of Health Read More »

Variability in Home Oxygen Therapy Practices for Bronchopulmonary Dysplasia in Japan: A Questionnaire Survey

Ryo Ogawa, Masaki Hasebe, Tomohiko Nakamura, Fumihiko NambaNagano Children’s Hospital. Saitama Medical Center and Saitama Medical University.Japan Journal of Paediatrics and Child HealthJ Paediatr Child Health 2025; DOI: 10.1111/jpc.70150 AbstractAim: To examine variations in home oxygen therapy (HOT) initiation and management practices for bronchopulmonary dysplasia (BPD) among perinatal medical centres in Japan.Methods: A questionnaire survey was distributed to

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