Fresh (PHresh). Less than 1-2 years since publication

Hypoxanthine Promotes Pulmonary Vascular Remodeling and Adenosine Deaminase Is a Therapeutic Target for Pulmonary Hypertension

Jun-Zhuo Shi, Yong-Jian Zhu, Meng-Jie Zhang, Yi Yan, Lu-Ling Zhao, Hong-Da Zhang, Yan Liu, Wen-Hui Wu, Zhe Cheng, Chun-Guang Qiu, Jie-Jian Kou, Yun-Feng Zhou, Xiao-Bin Pang, Ji-Wang Chen, Xin-Mei Xie, Yang-Yang He, Zhi-Cheng JingHuaihe Hospital and Henan University. First Affiliated Hospital of Zhengzhou University. Shanghai Children’s Medical Center, National Children’s Medical Center and Shanghai Jiao […]

Hypoxanthine Promotes Pulmonary Vascular Remodeling and Adenosine Deaminase Is a Therapeutic Target for Pulmonary Hypertension Read More »

Echocardiographic Assessment of Pulmonary Hemodynamics and Right Ventricular Performance in Neonatal Murine Hypoxia

Kel Vin Woo, Philip T. Levy, Carla J. Weinheimer, Amanda L. Hauck, Aaron Hamvas, David M. Ornitz, Attila Kovacs, Gautam K. SinghWashington University School of Medicine. Boston Children’s Hospital, Department of Pediatrics and Harvard Medical School. Ann and Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg School of Medicine. Children’s Hospital Michigan

Echocardiographic Assessment of Pulmonary Hemodynamics and Right Ventricular Performance in Neonatal Murine Hypoxia Read More »

Risk Factors and Predictors of Mechanical Ventilation in Neonates With Meconium Aspiration Syndrome: A Retrospective Study at King Salman Armed Forces Hospital, Tabuk, Saudi Arabia

Abdulaziz A. Bedaiwi, Muhanned Amawi, Wegdan MawlanaKing Salman Armed Forces Hospital.Saudi Arabia CureusCureus 2025; 17: DOI: 10.7759/cureus.88486 AbstractBackground: Meconium aspiration syndrome (MAS) is a critical neonatal condition predominantly associated with term and post-term pregnancies, characterized by the aspiration of meconium-stained amniotic fluid (MSAF) leading to severe respiratory distress. Despite advances in obstetric and neonatal care, MAS

Risk Factors and Predictors of Mechanical Ventilation in Neonates With Meconium Aspiration Syndrome: A Retrospective Study at King Salman Armed Forces Hospital, Tabuk, Saudi Arabia Read More »

Four decades of heart-lung transplantation: Milestones and outcomes in advanced cardiorespiratory failure

L. Lily Rosenthal, Anna Maria Mühlbauer, Carola Grinninger, Nikolaus A. Haas, Heinrich Netz, Robert Dalla Pozza, Jürgen Hörer, Sebastian Michel, R. Schramm, D. Graetz, Christian HaglLMU University Hospital Munich. Clinic Bogen. Heart and Diabetes Centre North Rhine-Westphalia. Clinic Gauting.Germany European Society of Cardiology Heart FailureESC Heart Fail 2025; DOI: 10.1002/ehf2.15411 AbstractAims: Heart-lung transplantation (HLTx) remains a life-saving intervention

Four decades of heart-lung transplantation: Milestones and outcomes in advanced cardiorespiratory failure Read More »

Revived role of reverse Potts shunt in management of paediatric severe pulmonary hypertension

Zhangwei Wang, Honghao Fu, Shoujun LiChinese Academy of Medical Sciences and Peking Union Medical College, National Center for Cardiovascular Diseases and Fuwai Hospital.China Cardiology in the YoungCardiol Young 2025; DOI: 10.1017/S1047951125101352 AbstractPulmonary artery hypertension in children is a progressive, fatal disease secondary to a variety of causes leading to right ventricular dysfunction. Traditional treatments include lung

Revived role of reverse Potts shunt in management of paediatric severe pulmonary hypertension Read More »

Tracheostomy and Chronic Ventilator Dependence After Congenital Diaphragmatic Hernia Repair: Long-Term Outcomes

Sarah D. King, Keerthi Burgi, Erin E. Perrone, George B. Mychaliska, Amy G. Filbrun, Joseph T. ChurchUniversity of Michigan and University of Michigan Medical School. United States Journal of Surgical ResearchJ Surg Res 2025; 314: 567-573DOI: 10.1016/j.jss.2025.07.052 AbstractIntroduction: There are limited data regarding long-term outcomes in patients with congenital diaphragmatic hernia (CDH) who require tracheostomy with chronic

Tracheostomy and Chronic Ventilator Dependence After Congenital Diaphragmatic Hernia Repair: Long-Term Outcomes Read More »

Clinical Care for Cardiovascular Disease in Patients With Williams-Beuren Syndrome

R. Thomas Collins II, Verena Gravenhorst, Gilles Faury, Joanna Kwiatkowska, Christian E. H. Schmelzer, Heike Schneider, Anna Waldoch, Rainer PankauUniversity of Kentucky College of Medicine. University Medical Center and Georg-August-University Göttingen. Université Grenoble. Medical University of Gdańsk. Fraunhofer Institute for Microstructure of Materials and Systems. University Medical Center Schleswig-Holstein and Christian-Albrechts-University.United States, Germany, France and

Clinical Care for Cardiovascular Disease in Patients With Williams-Beuren Syndrome Read More »

Decreased smooth muscle cells and fibrous thickening of the tunica media in peripheral pulmonary artery stenosis in Alagille syndrome

Yosuke Ogawa, Amane Yamamoto, Sho Yamazawa, Masako Ikemura, Yasutaka Hirata, Ryo InuzukaUniversity of Tokyo Hospital.Japan Cardiovascular PathologyCardiovasc Pathol 2025; DOI: 10.1016/j.carpath.2024.107677 AbstractAlagille syndrome is caused by mutations in genes involved in NOTCH signaling, specifically JAG1 and NOTCH2, and is associated with a high rate of peripheral pulmonary artery stenosis. In this study, we report the case

Decreased smooth muscle cells and fibrous thickening of the tunica media in peripheral pulmonary artery stenosis in Alagille syndrome Read More »

Chronic cyanosis since infancy: Unveiling a giant right pulmonary arteriovenous malformation

Dian Komalaa, Harry Galuh Nugrahaa, Firman Ramadhana, Rais Khairuddina, Rahmat Budi Kuswiyantob, Putria Rayani ApandiUniversitas Padjadjaran.Indonesia Radiology Case ReportsRadiol Case Rep 2025; 20: 5353-5356DOI: 10.1016/j.radcr.2025.06.084 AbstractGiant pulmonary arteriovenous malformations (PAVMs) are rare vascular anomalies involving direct connections between pulmonary arteries and veins, leading to right-to-left shunting and systemic hypoxemia. While small PAVMs may be asymptomatic, larger

Chronic cyanosis since infancy: Unveiling a giant right pulmonary arteriovenous malformation Read More »

Early postnatal right-to-left patent ductus arteriosus shunting and severe outcomes in neonates with congenital diaphragmatic hernia: a retrospective cohort study

Jung Il Kwak, Juhee Park, Mi Jin Kim, Kyusang Yoo, Bo Kyeong Jin, Tae-Gyeong Kim, Joo Hyung Roh, Ha Na Lee, Keon Hee Seol, Chae Young Kim, Soo Hyun Kim, Jiyoon Jeong, Byong Sop Lee, Euiseok JungAsan Medical Center Children’s Hospital and University of Ulsan College of Medicine. BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-05986-x

Early postnatal right-to-left patent ductus arteriosus shunting and severe outcomes in neonates with congenital diaphragmatic hernia: a retrospective cohort study Read More »

Scroll to Top