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Combined haptoglobin and hemopexin therapy for the treatment of cardiopulmonary dysfunction in sickle cell disease

Melissa J. Lucero, Christina Lisk, Delaney Swindle, Francesca Cendali, Saini Setua, Kiruphagaran Thangaraju, Alamzeb Khan, David I. Pak, Quintin O’Boyle, Shuwei Lu, Robert Tolson, Seth Zaeske, Saqib Khan, Nishant Rana, Natalie Westover, Pavel Davizon-Castillio, Gemlyn George, Kathryn Hassell, Rachelle Nuss, Nathan Brinkman, Thomas Gentinetta, Christy Niemeyer, Pedro Cabrales, Andre Palmer, Angelo D’Alessandro, Paul W. Buehler, […]

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Pediatric Pulmonary Hypertension Associated With Treatment of Myeloproliferative Disorders and Malignant Tumors

Ayako Chida‐Nagai, Yukayo Terashita, Shinsuke Hirabayashi, Hirokuni Yamazawa, Yuko Cho, Atsushi ManabeHokkaido University.Japan Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70165 AbstractPulmonary hypertension (PH) is a severe complication observed in pediatric patients after hematopoietic cell transplantation or chemotherapy. A review of records at Hokkaido University Hospital (2014-2024) identified four cases of PH, each with different etiologies, including

Pediatric Pulmonary Hypertension Associated With Treatment of Myeloproliferative Disorders and Malignant Tumors Read More »

Juvenile systemic sclerosis with rapid progression and multisystem involvement in an adolescent

Swati Khapekar/Majarikar, Revat Meshram, Dinesh Hinge, Amar Taksande, Mangesh Deshmukh, Abhijit Kumar AgrawalDMIHER University. Fiona Stanley Hospital.India and Australia British Medical Journal Case ReportsBMJ Case Rep 2025; 18: DOI: 10.1136/bcr-2025-264899 AbstractJuvenile systemic sclerosis (JSSc) is a rare, progressive autoimmune disorder that can affect the skin, musculoskeletal system, gastrointestinal tract, lungs, heart, kidney and endocrine glands. Clinical presentation varies

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Technical Challenges in Studying Infectious Disease-Associated Pulmonary Hypertension in Low- and Middle-Income Countries with Limited Resources

Jennifer van Heerden, Irina Mbanze, Elizabeth Louw, Olukayode Aremu, Anastase Dzudie, Ana Mocumbi, Threnesan Naidoo, Brian Allwood, Friedrich ThienemannUniversity of Oxford. Maputo Central Hospital. University of Cape Town. University of Stellenbosch. Douala General Hospital. Universidade Eduardo Mondlane. Walter Sisulu University. University of Zurich.United Kingdom, Mozambique, South Africa, Cameroon and Switzerland Infectious Disease ReportsInfect Dis Rep

Technical Challenges in Studying Infectious Disease-Associated Pulmonary Hypertension in Low- and Middle-Income Countries with Limited Resources Read More »

Pre-existing pulmonary arterial hypertension decompensation associated with e-cigarettes in an adolescent

James Andrew Bishara, Patrick EversOregon Health and Science University and Doernbecher Children’s Hospital.United States Cardiology in the YoungCardiol Young 2025; DOI: 10.1017/S1047951125100577 AbstractAn adolescent girl with a long-standing history of pulmonary arterial hypertension experienced severe clinical decompensation after starting to use e-cigarettes. A combination of e-cigarette cessation, atrial septostomy, increasing treprostinil, and initiation of sotatercept led

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Right atrial function is impaired in pediatric pulmonary arterial hypertension: a multi-center cardiac MRI study

Kimberley G. Miles, Hieu T. Ta, Kurt R. Bjorkman, Zhiqian Gao, Nicholas J. Ollberding, Russel Hirsch, D. Dunbar Ivy, Sean M. Lang, Michelle Cash, Melissa Magness, Meredith O’Neil, Kimberly Luebbe, Benjamin S. Frank, Paul J. CritserCincinnati Children’s Hospital Medical Center and University of Cincinnati College of Medicine. Helen DeVos Children’s Hospital. University of Colorado School

Right atrial function is impaired in pediatric pulmonary arterial hypertension: a multi-center cardiac MRI study Read More »

Global, Regional, and National Burden of Pulmonary Arterial Hypertension from 1990 to 2021 and Projections to 2040: A Systematic Analysis of Incidence, Mortality, and Disability-Adjusted Life Years

Lin-Ling Yu, Ding-Sheng Jiang, Xiong Wang, Ze-Min Fang, Wei-Hong Chen, JinZhu Zhao, Xin Yi, Wei LuTongji Hospital, Tongji Medical College and Huazhong University of Science and Technology. Chinese Academy of Medical Sciences. Renmin Hospital of Wuhan University. China Current Medical ScienceCurr Med Sci 2025; DOI: 10.1007/s11596-025-00108-1 AbstractObjective: Pulmonary arterial hypertension (PAH) poses a growing global health challenge,

Global, Regional, and National Burden of Pulmonary Arterial Hypertension from 1990 to 2021 and Projections to 2040: A Systematic Analysis of Incidence, Mortality, and Disability-Adjusted Life Years Read More »

Clinical Profile and Morbidity Patterns in Neonates Born Through Meconium-Stained Amniotic Fluid Based on a Prospective Observational Study From a Rural Tertiary Care Center in India

Gaurav Dutta, Suresh Kumar Yadav, Ekansh Rathoria, Rohitash Lahari, Akash Srivastava, Richa RathoriaHind Institute of Medical Sciences.India CureusCureus 2025; 17: DOI: 10.7759/cureus.90332 AbstractBackground: Meconium observed in the amniotic fluid during delivery may warrant clinical monitoring due to potential neonatal complications. This study aimed to assess the incidence, risk factors, and outcomes associated with meconium aspiration syndrome

Clinical Profile and Morbidity Patterns in Neonates Born Through Meconium-Stained Amniotic Fluid Based on a Prospective Observational Study From a Rural Tertiary Care Center in India Read More »

Efficacy and Safety of Pulmonary Vasodilator and Inodilator Drugs in Congenital Heart Disease Surgery: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

Martina Ollosu, Vincenzo Francesco Tripodiy, Carlotta Aresu, Giammarco Ledda, Francesca Manai, Chiara Marini, Mario Musu, Mariachiara Ippolitoz, Andrea Cortegianiz, Gabriele Finco, Salvatore SardoUniversity of Cagliari. “Gaetano Martino” University Hospital. University Hospital Policlinico Paolo Giaccone. Italy Journal of Cardiothoracic and Vascular AnesthesiaJ Cardiothorac Vasc Anesth 2025; DOI: 10.1053/j.jvca.2025.08.053 AbstractBackground: Perioperative management of congenital heart disease (CHD) surgery presents

Efficacy and Safety of Pulmonary Vasodilator and Inodilator Drugs in Congenital Heart Disease Surgery: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials Read More »

Turner syndrome with pulmonary arteriovenous malformation: a case report

Huibin Guo, Hongqiao Chen, Sihao Chen, Shilong TangUniversity-Town Hospital of Chongqing Medical University. Children’s Hospital of Chongqing Medical University.China Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2025; 12: DOI: 10.3389/fcvm.2025.1603250 AbstractTurner syndrome (TS) is the most common sex chromosome abnormality disorder, caused by complete or partial absence of the X chromosome, its clinical manifestations primarily include short

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