Filed (PHiled). Greater than 1-2 years since publication

Morbidity in giant omphaloceles: Predictive factors and management strategies

Laura Martou, Amulya K. SaxenaChelsea Children’s Hospital and Imperial College London.United Kingdom Acta PaediatricaActa Pediatr 2024; DOI: 10.1111/apa.17387 AbstractAim: To identify predictors of morbidity in GO through an analysis of associated anomalies, defect characteristics and management strategies.Methods: PubMed and Ovid EMBASE databases were searched from 2013 to 2023. Primary end points assessed correlation of morbidity with gestational age

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Cord blood transfusions in extremely low gestational age neonates to reduce severe retinopathy of prematurity: results of a prespecified interim analysis of the randomized BORN trial

Luciana Teofili, Patrizia Papacci, Carlo Dani, Francesco Cresi, Giulia Remaschi, Claudio Pellegrino, Maria Bianchi, Giulia Ansaldi, Maria Francesca Campagnoli, Barbara Vania, Domenico Lepore, Fabrizio Gaetano Saverio Franco, Marco Fabbri, Roberta Penta de Vera d’ Aragona, Anna Molisso, Enrico Beccastrini, Antonella Dragonetti, Lorenzo Orazi, Tina Pasciuto, Iolanda Mozzetta, Antonio Baldascino, Emanuela Locatelli, Caterina Giovanna Valentini, Carmen

Cord blood transfusions in extremely low gestational age neonates to reduce severe retinopathy of prematurity: results of a prespecified interim analysis of the randomized BORN trial Read More »

Animal models of pulmonary arterial hypertension associated with atrial septal defect

Li Wang, Ting Tang, Xiaochun Tian, Chang Peng, Shuqi WuGuizhou Children’s Hospital and Affiliated Hospital of Zunyi Medical University. China Scientific ReportsSci Rep 2024; 14: DOI: 10.1038/s41598-024-69002-5 AbstractPulmonary arterial hypertension (PAH) is a well-known complication of congenital heart disease (CHD). The lack of a satisfactory animal model for PAH associated with CHD (PAH-CHD) has limited progress

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Echocardiographic estimation of pulmonary arterial and right atrial pressures in children with congenital heart disease: a comprehensive prospective study and introduction of novel equations

Elaheh Malakan Rad, Reza Elhamian, Keyhan Sayadpour Zanjani, Reza Shabanian, Ehsan Aghaei Moghadam, Mohamad Taghi Majnoon, Aliakbar ZeinalooChildren’s Medical Center and Tehran University of Medical Sciences.Iran Journal of Cardiovascular ImagingJ Cardiovasc Imag 2024; 32: DOI: 10.1186/s44348-024-00023-4 AbstractBackground: Pediatric pulmonary hypertension (PH) is characterized by a mean pulmonary arterial pressure exceeding 20 mmHg. There is limited research on

Echocardiographic estimation of pulmonary arterial and right atrial pressures in children with congenital heart disease: a comprehensive prospective study and introduction of novel equations Read More »

Adenylyl Cyclase Isoform 6 in the Pulmonary Artery Is Inhibited by Hypoxia via Cysteine Nitrosylation

Saeid Maghsoudi, Vikram Bhatia, Martha Hinton, Nisha Singh, Modh Wasif Khan, Prashen Chelikani, Shyamala, DakshinamurtiUniversity of Manitoba Faculty of Health Sciences. University of Manitoba Children’s Hospital Research Institute of Manitoba. University of Manitoba College of Dentistry. Canada American Journal of Respiratory Cell and Molecular BiologyAm J Respir Cell Mol Biol 2024; DOI: 10.1165/rcmb.2023-0447OC AbstractPersistent pulmonary hypertension

Adenylyl Cyclase Isoform 6 in the Pulmonary Artery Is Inhibited by Hypoxia via Cysteine Nitrosylation Read More »

Hybrid treat-and-repair strategy for large patent ductus arteriosus: a proof-of-concept case report

Naoki Tsuboya, Yoshihide Mitani, Hiroyuki Ohashi, Hirofumi Sawada, Masahiro HirayamaMie University Graduate School of Medicine.Japan European Heart Journal Case ReportsEur Heart J Case Rep 2024; DOI: 10.1093/ehjcr/ytae354 AbstractBackground: In cases of atrial septal defect with pulmonary arterial hypertension (PAH), a treat-and-repair strategy that adopts pulmonary vasodilator therapy and subsequent defect closure is postulated to be effective. However,

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Prenatal Prognosis of Omphalocele Using Magnetic Resonance Imaging Measurement of Fetal Lung Volumes

Simon E. Dadoun, Matthew A. Shanahan, Christian M. Parobek, Brian A. Burnett, Alice King, Pamela Ketwaroo, Roopali V. Donepudi, April D. AdamsTexas Children’s Hospital and Baylor College of Medicine. United States American Journal of Obstetrics and Gynecology Maternal Fetal MedicineAm J Obstet Gynecol MFM 2024; DOI: 10.1016/j.ajogmf.2024.101457 AbstractBackground: Omphalocele is a congenital midline abdominal wall defect resulting

Prenatal Prognosis of Omphalocele Using Magnetic Resonance Imaging Measurement of Fetal Lung Volumes Read More »

Safety and Effectiveness of Selexipag in Pediatric Pulmonary Hypertension: A Retrospective Multi-Center Cohort Study

Benjamin S. Frank, Eliza R. Gentzler, Catherine M. Avitabile, Kathleen Miller-Reed, Zhaoxing Pan, Erika B. Rosenzweig, D. Dunbar Ivy, Usha S. KrishnanUniversity of Colorado School of Medicine and Children’s Hospital Colorado. Columbia University Irving Medical Center and Morgan Stanley Childrens Hospital of New York Presbyterian Hospital. University of Pennsylvania School of Medicine and Children’s Hospital

Safety and Effectiveness of Selexipag in Pediatric Pulmonary Hypertension: A Retrospective Multi-Center Cohort Study Read More »

Circulating High Mobility Group Box-1 Does Not Predict Pulmonary Arterial Hypertension in Children with Congenital Heart Disease: A Prospective Cohort Study

Bruno Caracci, Carolyne Pehora, Lee Benson, Benjamin E. Steinberg, Neil M. Goldenberg, Katherine TaylorHospital for Sick Children and University of Toronto. Canada Journal of Cardiothoracic and Vascular AnesthesiologyJ Cardiothorac Vasc Anesthesiol 2024; DOI: 10.1053/j.jvca.2024.07.020 AbstractObjectives: Pulmonary arterial hypertension (PAH) is a devastating complication of pediatric congenital heart disease (CHD). A recent study has identified the protein high

Circulating High Mobility Group Box-1 Does Not Predict Pulmonary Arterial Hypertension in Children with Congenital Heart Disease: A Prospective Cohort Study Read More »

Clinical presentation and surgical outcomes in patients with Shone’s complex: a systematic review

H. Shafeeq Ahmed, Purva Reddy Jayaram, Deeksha GuptaBangalore Medical College and Research Institute.India General Thoracic and Cardiovascular SurgeryGen Thorac Cardiovasc Surg 2024; DOI: 10.1007/s11748-024-02067-1 AbstractObjective: Shone’s complex comprises of a combination of congenital cardiac anomalies causing obstructions in the left ventricle’s inflow and outflow tracts. This systematic review aims to evaluate the clinical features and surgical outcomes

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