Filed (PHiled). Greater than 1-2 years since publication

A Comprehensive Review of Inhaled Nitric Oxide Therapy: Current Trends, Challenges, and Future Directions

Divyanshi Kaplish, Jayant D. Vagha, Revat J. Meshram, Sham LohiyaJawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & ResearchIndia CureusCureus 2024; 16:DOI: 10.7759/cureus.53558 AbstractThis comprehensive review explores the multifaceted landscape of inhaled nitric oxide (iNO) therapy, tracing its historical evolution, mechanisms of action, clinical applications, challenges, and future directions. The nitric oxide signaling pathway, […]

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Leukotriene B4 levels in CHD-associated paediatric pulmonary hypertension

Gamze Vuran, Murat Muhtar Yilmazer, Engin Gerceker, Cüneyt Zihni, Timur MeseUniversity of Health Sciences and İzmir Dr. Behçet Uz Pediatric Diseases and Surgery Training and Research Hospital.Turkey Cardiology in the YoungCardiol Young 2024;DOI: 10.1017/S1047951124000362 AbstractBackground: The aim of this study is to evaluate the role of leukotriene B4, an inflammatory mediator, in the development of pulmonary hypertension

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Neonatal persistent pulmonary hypertension related to a novel TBX4 mutation: case report and review of the literature

Chiara Maddaloni, Sara Ronci, Domenico Umberto De Rose, Iliana Bersani, Francesca Campi, Matteo Di Nardo, Francesca Stoppa, Rachele Adorisio, Antonio Amodeo, Alessandra Toscano, Maria Cristina Digilio, Antonio Novelli, Giovanni Chello, Annabella Braguglia, Andrea Dotta, Flaminia Calzolar“Bambino Gesù” Children’s Hospital IRCCS. Monaldi Hospital.Italy Italian Journal of PediatricsItal J Pediatr 2024; 50:DOI: 10.1186/s13052-024-01575-3 AbstractTBX4 gene, located on human

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Evaluation of Pre and Post-operative Pulmonary Artery Pressures in Children with Adenotonsillar Hypertrophy and Correlation with Chronicity: A Prospective Study on 50 Children

Khushboo Goel, Sanjeev Bhagat, Dinesh Kumar Sharma, Vishav Yadav, Peeyush Verma, Saivi RajdevGovernment Medical College. Employees State Insurance Model Hospital. India Indian Journal of Otolaryngology and Head and Neck SurgeryIndian J Otolaryngol Head Neck Surg 2024; 76: 639-644DOI: 10.1007/s12070-023-04235-w AbstractChildren with grade III or IV of adenotonsillar hypertrophy especially of a longer duration, may show cardiovascular

Evaluation of Pre and Post-operative Pulmonary Artery Pressures in Children with Adenotonsillar Hypertrophy and Correlation with Chronicity: A Prospective Study on 50 Children Read More »

Predictive Scoring System for Spontaneous Closure of Infant Ventricular Septal Defect: The P-VSD Score

Ah Young Kim, Nuri Tchah, Ching-Yu Lin, Jung Min Park, Wongi Woo, Chang Sin Kim, Se Yong Jung, Jae Young Choi, Jo Won JungSeverance Cardiovascular Hospital and Yonsei University College of Medicine. National Health Insurance Service Ilsan Hospital. Gangnam Severance Hospital.Republic of Korea Pediatric CardiologyPediatr Cardiol 2024; DOI: 10.1007/s00246-024-03434-8 AbstractVentricular septal defect (VSD) is a common

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RNA m6A methylation and regulatory proteins in pulmonary arterial hypertension

Zhe Wang, Yi-Xuan Zhang, Jun-Zhuo Shi, Yi Yan, Lu-Ling Zhao, Jie-Jian Kou, Yang-Yang He, Xin-Mei Xie, Si-Jin Zhang, Xiao-Bin PangHuaihe Hospital of Henan University. Shanghai Children’s Medical Center, National Children’s Medical Center and Shanghai Jiao Tong University School of Medicine. Guangdong Provincial People’s Hospital and Southern Medical University.China Hypertension ResearchHypertens Res 2024; DOI: 10.1038/s41440-024-01607-9 Abstractm6A (N6‑methyladenosine)

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Isolated atresia of the left pulmonary veins

Alberto Cabrera, Carlos Vazquez, Iñaki LekuonaHospital Infantil, Bilbao.Spain International Journal of CardiologyInt J Cardiol 1985; 7: 298-302DOI: 10.1016/0167-5273(85)90055-5 AbstractFour cases of congenital isolated atresia of the left pulmonary veins were observed over a 12-year period. The diagnosis was established through radionuclide pulmonary perfusion studies together with cardiac catheterization and pulmonary arteriography. Both procedures showed an elevated

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Surgical management of congenital and acquired pulmonary vein stenosis

Thomas L. Spray, Nancy D. BridgesThe Children’s Hospital of Philadelphia.United States Seminars in Thoracic and Cardiovascular Surgery Pediatric Cardiac Surgery AnnualSemin Thorac Cardiovasc Surg Pediatr Card Surg Ann 1999; 2: 177-188DOI: 10.1016/s1092-9126(99)70015-3 AbstractPulmonary vein stenosis describes a variety of entities with a variable clinical course. The basic pathologic process appears to be fibrous intimal thickening, which

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The evaluation of the SMAD1 rs1016792 polymorphism and gene expression on pulmonary hypertension due to congenital heart disease in children: a preliminary study

Adnan Selim Kimyon, Aysegul Cetinkaya, Oglu Hallioglu Kilinc, Nurcan ArasMersin University and Forum Yasam Hospital.Turkey Nucleosides Nucleotides and Nucleic AcidsNucleosides Nucleotides Nucleic Acids 2024; 26:DOI: 10.1080/15257770.2024.2322109 AbstractSmad Family Member (SMAD), a protein family responsible for transducing the signal induced by TGF-β into the nucleus, is thought to play a role in the pathology of many heart

The evaluation of the SMAD1 rs1016792 polymorphism and gene expression on pulmonary hypertension due to congenital heart disease in children: a preliminary study Read More »

Cardiac Implications of Adenotonsillar Hypertrophy and Obstructive Sleep Apnea in Pediatric Patients: A Comprehensive Systematic Review

Marco Zaffanello, Refika Hamutcu Ersu, Luana Nosetti, Giulio Beretta, Massimo Agosti, Giorgio PiacentiniUniversity of Verona. Children’s Hospital of Eastern Ontario and University of Ottawa. F. Del Ponte” Hospital and University of Insubria.Italy and Canada ChildrenChildren 2024; DOI: 10.3390/children11020208 AbstractThis review investigates the relationship between pediatric obstructive sleep apnea, often associated with adenotonsillar hypertrophy, and cardiovascular health,

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