Filed (PHiled). Greater than 1-2 years since publication

Physical Activity Measured by Hip-Anchored Accelerometry in Pediatric Pulmonary Hypertension: Association with Disease Severity & Estimation of Minimal Important Differences

Mark-Jan Ploegstra, Rosaria J. Ferreira, Chantal Lokhorst, Eva Gouwy, Suzanne S. J. Schwartz, Marlies G. Haarman, Matthieu Villeneuve, Dimitri Stamatiadis, Johannes M. Douwes, Rolf M. F. BergerBeatrix Children’s Hospital, University Medical Center Groningen andUniversity of Groningen. Actelion Pharmaceuticals.Netherlands and Switzerland ChestChest 2025; DOI: 10.1016/j.chest.2025.01.038 AbstractBackground: Pediatric pulmonary hypertension (PH) is a severe incurable disease with poor prognosis.

Physical Activity Measured by Hip-Anchored Accelerometry in Pediatric Pulmonary Hypertension: Association with Disease Severity & Estimation of Minimal Important Differences Read More »

A Cross-Species and Sex-Specific Meta-Analysis of Transcriptomic Studies of Pulmonary Hypertension

Lan Zhao, Christine M. Cunningham, Jason Hong, Stuti Agarwal, Ke Yuan, Vinicio A. de Jesus Perez, Mark R. NicollsStanford University. University of California, Los Angeles. Boston Children’s Hospital.United States American Journal of Respiratory Cell and Molecular BiologyAm J Respir Cell Mol Biol 2025; DOI: 10.1165/rcmb.2024-0410OC AbstractPulmonary hypertension (PH) is a life-threatening disease characterized by pulmonary vascular

A Cross-Species and Sex-Specific Meta-Analysis of Transcriptomic Studies of Pulmonary Hypertension Read More »

Response to Inhaled Nitric Oxide and Mortality Among Very Preterm Neonates With Pulmonary Hypertension

Michelle Baczynski, Dany Weisz, Laura Thomas, Stephanie Fevrier, Michael Castaldo, Amuchou Soraisham, Abbas Hyderi, Rula Agarushi, Soume Bhattacharya, Renjini Lalitha, Amneet Sidhu, Muzafar Gani Abdul Wahab, Gabriel Altit, Audrey Hébert, Deepak Louis, Yasser Elsayed, Souvik Mitra, Poorva Deshpande, Ashraf Kharrat, Faith Zhu, Joseph Ting, Eugene Yoon, Prakesh S. Shah, Amish Jain for the Canadian Neonatal

Response to Inhaled Nitric Oxide and Mortality Among Very Preterm Neonates With Pulmonary Hypertension Read More »

Refractory Chylothorax and Ventricular Hypertrophy Treated with Trametinib in a Patient with Noonan Syndrome: 18-Month Follow-Up

Antonia Pascarella, Giuseppe Limongelli, Alessandro De Falco, Elia Marco Paolo Minale, Giangiacomo Di Nardo, Giovanni Maria Di Marco, Geremia Zito Marinosci, Giorgia Olimpico, Paolo Siani, Daniele De BrasiSantobono-Pausilipon Children’s Hospital. University of Campania “Luigi Vanvitelli” and Monaldi Hospital. University “Federico II”. Italy ChildrenChildren 2024; 11: DOI: 10.3390/children11111342 AbstractRASopathies are a group of genetic syndromes caused by

Refractory Chylothorax and Ventricular Hypertrophy Treated with Trametinib in a Patient with Noonan Syndrome: 18-Month Follow-Up Read More »

Anti-fibroblast and anti-endothelial cell autoantibodies in pulmonary arterial hypertension (PAH) in patients with connective tissue diseases (CTD)

Benjamin Thoreau, Arthur Ranaud, Philippe Chafey, Guilhem Clary, Morgane La Gall, Cédric Broussard, Odile Launay, David Launay, Eric Hachulla, Christophe Deligny, Alban-Elouen Baruteau, Anaïs Vallet-Pichard, Benjamin Chaigne, Azzeddine Yaici, Oliver Sitbon, David Montani, Marc Humbert, Luc MouthonUniversité Paris Cité. Hôpital Cochin and Assistance Publique-Hôpitaux de Pari. de l’Est et de l’Ouest. Hôpital Pierre Zobda-Quitman. Nantes

Anti-fibroblast and anti-endothelial cell autoantibodies in pulmonary arterial hypertension (PAH) in patients with connective tissue diseases (CTD) Read More »

Detection of pulmonary hypertension in preterm infants with bronchopulmonary dysplasia using oxygen saturation data

Pravitha Ramanand, Premananda Indic, Samuel J. Gentle, Namasivayam AmbalavananUniversity of Texas at Tyler. University of Alabama at Birmingham.United States Pediatric ResearchPediatr Res 2025; DOI: 10.1038/s41390-025-03891-8 AbstractBackground: Pulmonary hypertension (PH) complicates the clinical course of bronchopulmonary dysplasia (BPD) in preterm infants, increasing risk of mortality and other morbidities. Early detection of PH may provide the clinical opportunity for

Detection of pulmonary hypertension in preterm infants with bronchopulmonary dysplasia using oxygen saturation data Read More »

Continuous positive airway pressure versus conventional oxygen therapy in meconium aspiration syndrome: a randomized controlled trial

Arifa Mustaqeem, Anita Yadav, Jogender Kumar, Pradeep DebataVardhman Mahavir Medical College and Safdarjung Hospital. Post Graduate Institute of Medical Education and Research. India Journal of Tropical PediatricsJ Trop Pediatr 2025; 71: DOI: 10.1093/tropej/fmaf002 AbstractNeonates with meconium aspiration syndrome (MAS) frequently require respiratory support. However, the initial mode of respiratory support in these patients remains unclear. We

Continuous positive airway pressure versus conventional oxygen therapy in meconium aspiration syndrome: a randomized controlled trial Read More »

MiR-25-3p regulates pulmonary arteriovenous malformation after Glenn procedure in patients with univentricular heart via the PHLPP2-HIF-1α axis

Junpei Kawamura, Munekazu Yamakuchi, Kentaro Ueno, Teruto Hashiguchi, Yasuhiro OkamotoKagoshima University. Japan Scientific ReportsSci Rep 2025; 15: DOI: 10.1038/s41598-025-88840-5 AbstractThe detailed mechanism of pulmonary arteriovenous malformations after Glenn surgery (G-PAVMs) in cyanotic congenital heart disease (CHD) remains unclear. Microarray in situ hybridization was performed to assess the miRNA (miRNA) profiles of serum from pediatric patients (0-6

MiR-25-3p regulates pulmonary arteriovenous malformation after Glenn procedure in patients with univentricular heart via the PHLPP2-HIF-1α axis Read More »

Embolotherapy for pulmonary arteriovenous malformations in the pediatric population with hereditary hemorrhagic telangiectasias – a retrospective case series

Haseeb Mukhtar, Vivek Iyer, Nadir Demirel, Emily C. Bendel, Haraldur Bjarnason, Sanjay MisraMayo Clinic.United States Journal of Vascular and Interventional RadiologyJ Vasc Interv Radiol 2025; DOI: 10.1016/j.jvir.2025.01.047 AbstractPurpose: To document the outcomes of embolotherapy for pulmonary arteriovenous malformation (pAVM) management, and investigate factors associated with pAVM persistence after embolotherapy in pediatric patients with hereditary hemorrhagic telangiectasia (HHT).Materials

Embolotherapy for pulmonary arteriovenous malformations in the pediatric population with hereditary hemorrhagic telangiectasias – a retrospective case series Read More »

Inhalation of the Novel Tryptophan Hydroxylase 1 Inhibitor TPT-004 Alleviates Pulmonary Arterial Hypertension in Rats

Ekaterina Legchenko, Philippe Chouvarine, Klea Hysko, Fatimunnisa Qadri, Radoslw Wesolowski, Edgar Specker, Silke Glage, Martin Meier, Katharina Schwarz, Joerg Heineke, Gerhard Pohlmann, Mehmet Ramazanoglu, Michael Bader, Georg HansmannHannover Medical School. Heidelberg University Medical Faculty Mannheim. Max-Delbrück-Center for Molecular Medicine. Leibniz-Forschungsinstitut für Molekulare Pharmakologie. Fraunhofer Institute for Toxicology and Experimental Medicine. Max Delbrück Center for Molecular

Inhalation of the Novel Tryptophan Hydroxylase 1 Inhibitor TPT-004 Alleviates Pulmonary Arterial Hypertension in Rats Read More »

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