Filed (PHiled). Greater than 1-2 years since publication

Pediatric Population Pharmacokinetic Modeling and Exposure-Response Analysis of Ambrisentan in Pulmonary Arterial Hypertension and Comparison With Adult Data

Malek Okour, Mita M. Thapar, Colm Farrell, Mary Ann Lukas, Maurice Beghetti, Misba BeeraheeGlaxo Smith Kline. ICON Clinical Research. University of Geneva and Centre Universitaire Romand de Cardiologie et Chirurgie Cardiaque Pédiatrique.United States, United Kingdom and Switzerland Journal of Clinical PharmacologyJ Clin Pharmacol 2022; DOI: 10.1002/jcph.2199 AbstractThis study aimed to develop a population pharmacokinetic (PK) model […]

Pediatric Population Pharmacokinetic Modeling and Exposure-Response Analysis of Ambrisentan in Pulmonary Arterial Hypertension and Comparison With Adult Data Read More »

International practice heterogeneity in pre-transplant management of pulmonary hypertension related to pediatric left heart disease

Rachel K. Hopper, Oscar van der Have, Seth A. Hollander, Anne I. Dipchand, Valeria Perez de Sa, Jeffery A. Feinstein, Karin Tran-LundmarkStanford University and Lucille Packard Children’s Hospital. Lund University. Skane University Hospital. University of Toronto and the Hospital for Sick ChildrenUnited States, Sweden and Canada Pediatric TransplantationPediatr Transplant 2023; DOI: 10.1111/petr.14461 AbstractBackground: Elevated pulmonary vascular resistance

International practice heterogeneity in pre-transplant management of pulmonary hypertension related to pediatric left heart disease Read More »

Synchrotron-based phase-contrast micro-CT as a tool for understanding pulmonary vascular pathobiology and the 3-D microanatomy of alveolar capillary dysplasia

Christian Norvik, Christian Karl Westöö, Niccolò Peruzzi, Goran Lovric, Oscar van der Have, Rajmund Mokso, Ida Jeremiasen, Hans Brunnström, Csaba Galambos, Martin Bech, Karin Tran-LundmarkLund University. École Polytechnique Fédérale de Lausanne. Swiss Light Source. University of Colorado.Sweden, Switzerland and United States American Journal of Physiology Lung cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol

Synchrotron-based phase-contrast micro-CT as a tool for understanding pulmonary vascular pathobiology and the 3-D microanatomy of alveolar capillary dysplasia Read More »

Monitoring and evaluation of the surgical Potts shunt physiology using 4-dimensional flow magnetic resonance imaging

Michael Schafer, Benjamin S. Frank, R. Mark Grady, Pirooz Eghtesady, Max B. Mitchell, James Jaggers, D. Dunbar IvyWashington University and St. Louis Children’s Hospital. University of Colorado and Children’s Hospital Colorado.United States Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2022; 164: 331-341DOI: 10.1016/j.jtcvs.2021.11.025 AbstractObjective: The reversed Potts shunt is an increasingly applied mode of surgical

Monitoring and evaluation of the surgical Potts shunt physiology using 4-dimensional flow magnetic resonance imaging Read More »

Biomarkers of Pulmonary Hypertension Are Altered in Children with Down Syndrome and Pulmonary Hypertension

Megan Griffiths, Jun Yang, Dhananjay Vaidya, Melanie Nies, Stephanie Brandal, D. Dunbar Ivy, Francis Hickey, Kristine Wolter-Warmerdam, Eric D. Austin, Mary Mullen, Michael W. Pauciulo, Katie A. Lutz, Erika B. Rosenzweig, Russel Hirsch, Delphine Yung, William C. Nichols, Allen D. EverettJohns Hopkins University. University of Colorado and Children’s Hospital Colorado. Vanderbilt University. Harvard University and

Biomarkers of Pulmonary Hypertension Are Altered in Children with Down Syndrome and Pulmonary Hypertension Read More »

Cardiac Catheterization and Hemodynamics in a Multicenter Cohort of Children with Pulmonary Hypertension

Erika B. Rosenzweig, Angela Bates, Mary P. Mullen, Steven H. Abman, Eric D. Austin, Allen Everett, Jeffrey Fineman, Jeffrey Feinstein, Rachel K. Hopper, John P. Kinsella, Usha S. Krishnan, Minmin Lu, Kenneth D, Mandl, J. Usha Raj, Nidhy Varghese, Delphene Yung, Stephanie S. Handler, Lynn A. SleeperPediatric Pulmonary Hypertension NetworkUnited States and Canada Annals of

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Diagnosis and management of pulmonary hypertension in congenital diaphragmatic hernia

Shazia Bombal, Neil PatelStanford University and Lucille Packard Children’s Hospital. Royal Hospital for Children, Glasgow. United States and United Kingdom Seminars in Fetal and Neonatal MedicineSemin Fetal Neonatal Med 2022; 27: DOI: 10.1016/j.siny.2022.101383 AbstractCongenital diaphragmatic hernia (CDH) contributes to neonatal morbidity and mortality worldwide. Pulmonary hypertension (PH) is a key component of CDH pathophysiology and critical

Diagnosis and management of pulmonary hypertension in congenital diaphragmatic hernia Read More »

Diagnosis and management of pulmonary hypertension in infants with bronchopulmonary dysplasia

Philip T. Levy, Jonathan Levin, Kristen T. Leeman, Mary P. Mullen, Georg Hansmann, Stella KourembanasHarvard Medical School and Boston Children’s Hospital. Hannover Medical School.United States and Germany Seminars in Fetal and Neonatal MedicineSemin Fetal Neonatal Med 2022; 27: DOI: 10.1016/j.siny.2022.101351 AbstractChronic pulmonary hypertension of infancy (cPHi) is a heterogeneous disease process that contributes to morbidity and

Diagnosis and management of pulmonary hypertension in infants with bronchopulmonary dysplasia Read More »

Pulmonary Hypertension in Children with Down Syndrome: Results from the Pediatric Pulmonary Hypertension Network Registry

Rachel K. Hopper, Steven H. Abman, Eleni G. Elia, Catherine M. Avitabile, Delphine Yung, Mary P. Mullen, Eric D. Austin, Angela Bates, Stephaie S. Handler, Jeffery A Feinstein, D. Dunbar Ivy, John P. Kinsella, Kenneth D. Mandel, J. Usha Raj, Lynn A. SleeperPediatric Pulmonary Hypertension Network InvestigatorsUnited States and Canada Journal of PediatricsJ Pediatr 2023;

Pulmonary Hypertension in Children with Down Syndrome: Results from the Pediatric Pulmonary Hypertension Network Registry Read More »

High Altitude Pulmonary Edema in Children: A Single Referral Center Evaluation

Ann M. Giesenhagen, D. Dunbar Ivy, John T. Brinton, Maxene R. Meier, Jason P. Weinman, Deborah R. LiptzinUniversity of Colorado and Children’s Hospital Colorado Anschutz CampusUnited States Journal of PediatricsJ Pediatr 2019; 210: 106-111DOI: 10.1016/j.jpeds.2019.02.028 AbstractObjective: To describe the clinical features of children who presented to Children’s Hospital Colorado (CHCO) with High-Altitude Pulmonary Edema (HAPE). Study

High Altitude Pulmonary Edema in Children: A Single Referral Center Evaluation Read More »

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