Filed (PHiled). Greater than 1-2 years since publication

Extracellular vesicles derived from endothelial cells in hypoxia contribute to pulmonary artery smooth muscle cell proliferation in-vitro and pulmonary hypertension in mice

Tianji Chen, Miranda R. Sun, Qiyuan Zhou, Alyssa M. Guzman, Ramaswamy Ramchandran, Jiwang Chen, Balaji Ganesh, J. Usha RajUniversity of Illinois at Chicago. United States Pulmonary CirculationPulm Circ 2022; 12: DOI: 10.1002/pul2.12014 AbstractIn the lung, communication between pulmonary vascular endothelial cells (PVEC) and pulmonary artery smooth muscle cells (PASMC) is essential for the maintenance of vascular […]

Extracellular vesicles derived from endothelial cells in hypoxia contribute to pulmonary artery smooth muscle cell proliferation in-vitro and pulmonary hypertension in mice Read More »

High haemoglobin levels at the time of occlusion predict worse outcome for patients with patent ductus arteriosus and pulmonary hypertension

Kanta Kishi, Jirayut Jarutach, Yinn Khurn Wong, Marhisham Che Mood, Geetha Kandhavello, Mazeni Alwi, Ming Chern Leong Osaka Medical and Pharmaceutical University. Prince of Songkla University. Serdang Hospital. Sarawak General Hospital. Institut Jantung Negara.Japan, Thailand and Malaysia Cardiology in the YoungCardiol Young 2022; DOI: 10.1017/S104795112200244X AbstractIntroduction: Current guidelines discourage shunt closure in patients with pulmonary vascular resistance

High haemoglobin levels at the time of occlusion predict worse outcome for patients with patent ductus arteriosus and pulmonary hypertension Read More »

Normal Echocardiographic Reference Values of the Right Ventricular to Left Ventricular Endsystolic Diameter Ratio and the Left Ventricular Endsystolic Eccentricity Index in Healthy Children and in Children With Pulmonary Hypertension

Sabrina Schweintzger, Stefan Kurath-Koller, Ante Burmas, Gernot Grangl, Andrea Fandl, Nathalie Noessler, Alexander Avian, Andreas Gamillscheg, Philippe Chouvarine, Georg Hansmann, Martin KoesnbergerMedical University Graz. Hannover Medical School. European Pediatric Pulmonary Vascular Disease Network. Austria and Germany Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2022; DOI: 10.3389/fcvm.2022.950765 AbstractBackground: An accurate assessment of the right and left ventricle and their

Normal Echocardiographic Reference Values of the Right Ventricular to Left Ventricular Endsystolic Diameter Ratio and the Left Ventricular Endsystolic Eccentricity Index in Healthy Children and in Children With Pulmonary Hypertension Read More »

Large animal preclinical investigation into the optimal extracorporeal life support configuration for pulmonary hypertension and right ventricular failure

Rei Utika, John W. Stokes, W. Kelly Wu, Yatrik J. Patel, Jennifer R. Talackine, Nancy Cardwell, Clayne Benson, Ryan J. Lefevre, Susan Eagle, Caitlin Demarest, Elizabeth Simonds, Yuliya Tipograf, Michael Cortelli, David J. Skoog, Keith Cook, Erika B. Rosenzweig, Matthew BachettaVanderbilt University Medical Center. Advanced Respiratory Technologies LLC. Carnegie Mellon University. Columbia University Medical Center.United

Large animal preclinical investigation into the optimal extracorporeal life support configuration for pulmonary hypertension and right ventricular failure Read More »

Safety and tolerability of combination therapy with ambrisentan and tadalafil for the treatment of pulmonary arterial hypertension in children: Real-world experience

Azadeh Issapour, Benjamin Frank, Sarah Crook, Michelle D. Hite, Michelle L. Dorn, Erika B. Rosenzweig, D. Dunbar Ivy, Usha S. KrishnanColumbia University Irving Medical Center. University of Colorado and Children’s Hospital Colorado.United States Pediatric PulmonologyPediatr Pulmonol 2022; 57: 724-733DOI: 10.1002/ppul.25796 AbstractObjective: To describe the safety and tolerability of treatment with ambrisentan and tadalafil in pediatric pulmonary hypertension

Safety and tolerability of combination therapy with ambrisentan and tadalafil for the treatment of pulmonary arterial hypertension in children: Real-world experience Read More »

Distinguishing exercise intolerance in early-stage pulmonary hypertension with invasive exercise hemodynamics: Rest VE /VCO2 and ETCO2 identify pulmonary vascular disease

Farhan Raza, Naga Dharmavaram MD, Timothy Hess, Ravi Dhingra, James Runo, Amy Chybowski, Callyn Kozitza, Supria Batra, Evelyn M. Horn, Naomi Chesler, Marlowe EldridgeUniversity of Wisconsin-Madison. Weill Cornell Medicine. University of California-Irvine.United States Clinical CardiologyClin Cardiol 2022; 45: 742-751DOI: 10.1002/clc.23831 AbstractBackground: Among subjects with exercise intolerance and suspected early-stage pulmonary hypertension (PH), early identification of pulmonary vascular

Distinguishing exercise intolerance in early-stage pulmonary hypertension with invasive exercise hemodynamics: Rest VE /VCO2 and ETCO2 identify pulmonary vascular disease Read More »

Channelopathy Genes in Pulmonary Arterial Hypertension

Carrie L. Welch, Wendy K. ChungColumbia University Irving Medical Center.United States BiomoleculesBiomolecules 2022; 12: DOI: 10.3390/biom12020265 AbstractPulmonary arterial hypertension (PAH) is a rare, progressive vasculopathy with significant cardiopulmonary morbidity and mortality. The underlying pathogenetic mechanisms are heterogeneous and current therapies aim to decrease pulmonary vascular resistance but no curative treatments are available. Causal genetic variants can

Channelopathy Genes in Pulmonary Arterial Hypertension Read More »

Periostin-related progression of different types of experimental pulmonary hypertension: A role for M2 macrophage and FGF-2 signalling

Takashi Yoshida, Tetsutaro Nagaoka, Yuichi Nagata, Yoshifumi Suzuki, Takeo Tsutsumi, Sachiko Kuriyama, Junko Watanabe, Shinsaku Togo, Fumiyuki Takahashi, Masakazu Matsushita, Yusuke Joki, HakuohKonishi, Satoshi Nunomura, Kenji Izuhara, Simon J. Conway, Kazuhisa TakahashiJuntendo University Faculty of Medicine and Graduate School of Medicine. Saga Medical School. Indiana University School of Medicine.Japan and United States RespirologyRespirology 2022; 27:

Periostin-related progression of different types of experimental pulmonary hypertension: A role for M2 macrophage and FGF-2 signalling Read More »

Long-Term Follow-Up of Pediatric Patients with Severe Postoperative Pulmonary Hypertension After Correction of Congenital Heart Defects

Lars LindbergLund University and Skane University HospitalSweden Pediatric CardiologyPediatr Cardiol 2022; 43: 827-836DOI: 10.1007/s00246-021-02794-9 AbstractThe surgical repair of congenital heart defects in children with preoperative pulmonary hypertension (PH) is to varying degree associated with the occurrence of postoperative PH. The objective of this study was to follow up children with severe postoperative PH (pulmonary arterial/aortic pressure

Long-Term Follow-Up of Pediatric Patients with Severe Postoperative Pulmonary Hypertension After Correction of Congenital Heart Defects Read More »

Fetal endoscopic tracheal occlusion and pulmonary hypertension in moderate congenital diaphragmatic hernia

Roopali Donepudi, Michael A. Belfort, Alireza A. Shamshirsaz, Timothy C. Lee, Sundeep G. Keswani, Alice King, Nancy A. Ayres, Caraciolo J. Fernandes, Magdalena Sanz-Cortes, Ahmed A. Nassr, Andres F. Espinoza, Candace C. Style, Jimmy EspinozaBaylor College of Medicine.United States Journal of Maternal Fetal and Neonatal MedicineJ Mat Fetal Neonat Med 2022; 35: 6967-6972DOI: 10.1080/14767058.2021.1932806 AbstractObjective: To study

Fetal endoscopic tracheal occlusion and pulmonary hypertension in moderate congenital diaphragmatic hernia Read More »

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