Filed (PHiled). Greater than 1-2 years since publication

Pirfenidone ameliorates pulmonary arterial pressure and neointimal remodeling in experimental pulmonary arterial hypertension by suppressing NLRP3 inflammasome activation

Emmanouil Mavrogiannis, Quint A. J. Hagdorn, Venetia Bazioti, Johannes M. Douwes, Diederik E. Van Der Feen, Silke U. Oberdorf‐Maass, Marit Westerterp, Rolf M. F. BergerBeatrix Children’s Hospital, University Medical Center Groningen and University of GroningenNetherlands Pulmonary CirculationPulm Circ 2022; 12: DOI: 10.1002/pul2.12101 AbstractPulmonary arterial hypertension (PAH) is a fatal disease characterized by increased pulmonary arterial pressure, […]

Pirfenidone ameliorates pulmonary arterial pressure and neointimal remodeling in experimental pulmonary arterial hypertension by suppressing NLRP3 inflammasome activation Read More »

Pulmonary hypertension in extremely preterm infants: a call to standardize echocardiographic screening and follow-up policy

Sanne Arjaans, Elvira A. H. Zwart, Marc Roofthooft, Elisabeth M. W. Kooi, Arend F. Bos, Rolf M. F. BergerBeatrix Children’s Hospital, University Medical Center Groningen and University of GroningenNetherlands European Journal of PediatricsEur J Pediatr 2021; 180: 1855-1865DOI: 10.1007/s00431-021-03931-5 AbstractPulmonary hypertension (PH) is a frequent complication in extremely preterm born infants that seriously affects outcome. We

Pulmonary hypertension in extremely preterm infants: a call to standardize echocardiographic screening and follow-up policy Read More »

Risk stratification in adult and pediatric pulmonary arterial hypertension: A systematic review

Chantal Lokhorst, Sjoukje van der Werf, Rolf M. F. Berger, Johannes M. DouwesUniversity of Groningen, Beatrix Children’s Hospital and University Medical Center GroningenNetherlands Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2022; 9: 1035453DOI: 10.3389/fcvm.2022.1035453 AbstractIntroduction: Currently, risk stratification is the cornerstone of determining treatment strategy for patients with pulmonary arterial hypertension (PAH). Since the 2015 European Society of

Risk stratification in adult and pediatric pulmonary arterial hypertension: A systematic review Read More »

Paediatric pulmonary arterial hypertension: updates on definition, classification, diagnostics and management

Erika B. Rosenzweig, Steven H. Abman, Ian Adatia, Maurice Beghetti, Damien Bonnet, Sheila Haworth, D. Dunbar Ivy, Rolf M. F. BergerColumbia University and New York Presbyterian Hospital. University of Colorado and Children’s Hospital Colorado. Glenwood Children’s Heart Clinic. University Hospitals of Geneva and Lausanne. Hôpital Necker Enfants Malades, AP-HP, Université Paris Descartes. University College London.

Paediatric pulmonary arterial hypertension: updates on definition, classification, diagnostics and management Read More »

Correlation between Pulmonary Artery Pressure and Vortex Duration Determined by 4D Flow MRI in Main Pulmonary Artery in Patients with Suspicion of Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

Jean-Francois Deux, Lindsey A. Crowe, Leon Genecand, Anne-Lise Hachulla, Carl G. Glessgen, Stephane Noble, Maurice Beghetti, Jin Ning, Daniel Giese, Frederic Lador, Jean-Paul ValleeGeneva University Hospital. University of Geneva. Centre Universitaire Romand de Cardiologie et Chirurgie Cardiaque Pédiatrique. Siemens Medical Solutions. Siemens Healthcare GmbHSwitzerland, United States and Germany Journal of Clinical MedicineJ Clin Med 2022;

Correlation between Pulmonary Artery Pressure and Vortex Duration Determined by 4D Flow MRI in Main Pulmonary Artery in Patients with Suspicion of Chronic Thromboembolic Pulmonary Hypertension (CTEPH) Read More »

Pediatric Population Pharmacokinetic Modeling and Exposure-Response Analysis of Ambrisentan in Pulmonary Arterial Hypertension and Comparison With Adult Data

Malek Okour, Mita M. Thapar, Colm Farrell, Mary Ann Lukas, Maurice Beghetti, Misba BeeraheeGlaxo Smith Kline. ICON Clinical Research. University of Geneva and Centre Universitaire Romand de Cardiologie et Chirurgie Cardiaque Pédiatrique.United States, United Kingdom and Switzerland Journal of Clinical PharmacologyJ Clin Pharmacol 2022; DOI: 10.1002/jcph.2199 AbstractThis study aimed to develop a population pharmacokinetic (PK) model

Pediatric Population Pharmacokinetic Modeling and Exposure-Response Analysis of Ambrisentan in Pulmonary Arterial Hypertension and Comparison With Adult Data Read More »

International practice heterogeneity in pre-transplant management of pulmonary hypertension related to pediatric left heart disease

Rachel K. Hopper, Oscar van der Have, Seth A. Hollander, Anne I. Dipchand, Valeria Perez de Sa, Jeffery A. Feinstein, Karin Tran-LundmarkStanford University and Lucille Packard Children’s Hospital. Lund University. Skane University Hospital. University of Toronto and the Hospital for Sick ChildrenUnited States, Sweden and Canada Pediatric TransplantationPediatr Transplant 2023; DOI: 10.1111/petr.14461 AbstractBackground: Elevated pulmonary vascular resistance

International practice heterogeneity in pre-transplant management of pulmonary hypertension related to pediatric left heart disease Read More »

Synchrotron-based phase-contrast micro-CT as a tool for understanding pulmonary vascular pathobiology and the 3-D microanatomy of alveolar capillary dysplasia

Christian Norvik, Christian Karl Westöö, Niccolò Peruzzi, Goran Lovric, Oscar van der Have, Rajmund Mokso, Ida Jeremiasen, Hans Brunnström, Csaba Galambos, Martin Bech, Karin Tran-LundmarkLund University. École Polytechnique Fédérale de Lausanne. Swiss Light Source. University of Colorado.Sweden, Switzerland and United States American Journal of Physiology Lung cellular and Molecular PhysiologyAm J Physiol Lung Cell Mol

Synchrotron-based phase-contrast micro-CT as a tool for understanding pulmonary vascular pathobiology and the 3-D microanatomy of alveolar capillary dysplasia Read More »

Monitoring and evaluation of the surgical Potts shunt physiology using 4-dimensional flow magnetic resonance imaging

Michael Schafer, Benjamin S. Frank, R. Mark Grady, Pirooz Eghtesady, Max B. Mitchell, James Jaggers, D. Dunbar IvyWashington University and St. Louis Children’s Hospital. University of Colorado and Children’s Hospital Colorado.United States Journal of Thoracic and Cardiovascular SurgeryJ Thorac Cardiovasc Surg 2022; 164: 331-341DOI: 10.1016/j.jtcvs.2021.11.025 AbstractObjective: The reversed Potts shunt is an increasingly applied mode of surgical

Monitoring and evaluation of the surgical Potts shunt physiology using 4-dimensional flow magnetic resonance imaging Read More »

Biomarkers of Pulmonary Hypertension Are Altered in Children with Down Syndrome and Pulmonary Hypertension

Megan Griffiths, Jun Yang, Dhananjay Vaidya, Melanie Nies, Stephanie Brandal, D. Dunbar Ivy, Francis Hickey, Kristine Wolter-Warmerdam, Eric D. Austin, Mary Mullen, Michael W. Pauciulo, Katie A. Lutz, Erika B. Rosenzweig, Russel Hirsch, Delphine Yung, William C. Nichols, Allen D. EverettJohns Hopkins University. University of Colorado and Children’s Hospital Colorado. Vanderbilt University. Harvard University and

Biomarkers of Pulmonary Hypertension Are Altered in Children with Down Syndrome and Pulmonary Hypertension Read More »

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