Filed (PHiled). Greater than 1-2 years since publication Archives - Page 138 of 148

Safety and tolerability of combination therapy with ambrisentan and tadalafil for the treatment of pulmonary arterial hypertension in children: Real-world experience

Azadeh Issapour, Benjamin Frank, Sarah Crook, Michelle D. Hite, Michelle L. Dorn, Erika B. Rosenzweig, D. Dunbar Ivy, Usha S. KrishnanColumbia University Irving Medical Center. University of Colorado and Children’s Hospital Colorado.United States Pediatric PulmonologyPediatr Pulmonol 2022; 57: 724-733DOI: 10.1002/ppul.25796 AbstractObjective: To describe the safety and tolerability of treatment with ambrisentan and tadalafil in pediatric pulmonary hypertension

Safety and tolerability of combination therapy with ambrisentan and tadalafil for the treatment of pulmonary arterial hypertension in children: Real-world experience Read More »

Distinguishing exercise intolerance in early-stage pulmonary hypertension with invasive exercise hemodynamics: Rest V_E /VCO₂ and ETCO₂ identify pulmonary vascular disease

Farhan Raza, Naga Dharmavaram MD, Timothy Hess, Ravi Dhingra, James Runo, Amy Chybowski, Callyn Kozitza, Supria Batra, Evelyn M. Horn, Naomi Chesler, Marlowe EldridgeUniversity of Wisconsin-Madison. Weill Cornell Medicine. University of California-Irvine.United States Clinical CardiologyClin Cardiol 2022; 45: 742-751DOI: 10.1002/clc.23831 AbstractBackground: Among subjects with exercise intolerance and suspected early-stage pulmonary hypertension (PH), early identification of pulmonary vascular

Distinguishing exercise intolerance in early-stage pulmonary hypertension with invasive exercise hemodynamics: Rest V_E /VCO₂ and ETCO₂ identify pulmonary vascular disease Read More »

Channelopathy Genes in Pulmonary Arterial Hypertension

Carrie L. Welch, Wendy K. ChungColumbia University Irving Medical Center.United States BiomoleculesBiomolecules 2022; 12: DOI: 10.3390/biom12020265 AbstractPulmonary arterial hypertension (PAH) is a rare, progressive vasculopathy with significant cardiopulmonary morbidity and mortality. The underlying pathogenetic mechanisms are heterogeneous and current therapies aim to decrease pulmonary vascular resistance but no curative treatments are available. Causal genetic variants can

Channelopathy Genes in Pulmonary Arterial Hypertension Read More »

Long-Term Follow-Up of Pediatric Patients with Severe Postoperative Pulmonary Hypertension After Correction of Congenital Heart Defects

Lars LindbergLund University and Skane University HospitalSweden Pediatric CardiologyPediatr Cardiol 2022; 43: 827-836DOI: 10.1007/s00246-021-02794-9 AbstractThe surgical repair of congenital heart defects in children with preoperative pulmonary hypertension (PH) is to varying degree associated with the occurrence of postoperative PH. The objective of this study was to follow up children with severe postoperative PH (pulmonary arterial/aortic pressure

Long-Term Follow-Up of Pediatric Patients with Severe Postoperative Pulmonary Hypertension After Correction of Congenital Heart Defects Read More »

Fetal endoscopic tracheal occlusion and pulmonary hypertension in moderate congenital diaphragmatic hernia

Roopali Donepudi, Michael A. Belfort, Alireza A. Shamshirsaz, Timothy C. Lee, Sundeep G. Keswani, Alice King, Nancy A. Ayres, Caraciolo J. Fernandes, Magdalena Sanz-Cortes, Ahmed A. Nassr, Andres F. Espinoza, Candace C. Style, Jimmy EspinozaBaylor College of Medicine.United States Journal of Maternal Fetal and Neonatal MedicineJ Mat Fetal Neonat Med 2022; 35: 6967-6972DOI: 10.1080/14767058.2021.1932806 AbstractObjective: To study

Fetal endoscopic tracheal occlusion and pulmonary hypertension in moderate congenital diaphragmatic hernia Read More »

Endothelial progenitor cells stimulate neonatal lung angiogenesis through FOXF1-mediated activation of BMP9/ACVRL1 signaling

Guolun Wang, Bingqiang Wen, Zicheng Deng Arun Pradhan, Tanya V. Kalin, Yufang Zhang, Olena A. Kolesnichenko, Vladimir Ustiyan, Vladimir V. KalinichenkoCincinnati Children’s Hospital Medical Center and University of Cincinnati. United States Nature CommunicationsNat Commun 2022; DOI: 10.1038/s41467-022-29746-y AbstractPulmonary endothelial progenitor cells (EPCs) are critical for neonatal lung angiogenesis and represent a subset of general capillary cells

Endothelial progenitor cells stimulate neonatal lung angiogenesis through FOXF1-mediated activation of BMP9/ACVRL1 signaling Read More »

Non-Invasive Cardiac Output Determination Using Magnetic Resonance Imaging and Thermodilution in Pulmonary Hypertension

Lindsey A. Crowe, Léon Genecand, Anne-Lise Hachulla, Stéphane Noble, Maurice Beghetti, Jean-Paul Vallée, Frédéric LadorUniversity of Geneva and Geneva University Hospitals. Centre Universitaire Romand de Cardiologie et Chirurgie Cardiaque Pédiatrique and University of Geneva and Lausanne.Switzerland Journal of Clinical MedicineJ Clin Med 2022; 11: DOI: 10.3390/jcm11102717 AbstractMagnetic resonance imaging (MRI) can be used to measure cardiac

Non-Invasive Cardiac Output Determination Using Magnetic Resonance Imaging and Thermodilution in Pulmonary Hypertension Read More »

Anesthesia in Children With Pulmonary Hypertension: Clinically Significant Serious Adverse Events Associated With Cardiac Catheterization and Noncardiac Procedures

Mary Lyn Stein, Steven J. Staffa, Amy O’Brien Charles, Ryan Callahan, James A. DiNardo, Viviane G. Nasr, Morgan L. BrownHarvard Medical School and Boston Children’s Hospital.United States Journal of Cardiothoracic and Vascular AnesthesiaJ Cardiothorac Vasc Anesth 2022; 36: 1606-1616 DOI: 10.1053/j.jvca.2022.01.014 AbstractObjectives: To determine the incidence of clinically significant serious adverse events in a contemporary population of

Anesthesia in Children With Pulmonary Hypertension: Clinically Significant Serious Adverse Events Associated With Cardiac Catheterization and Noncardiac Procedures Read More »