Filed (PHiled). Greater than 1-2 years since publication

Full recovery of right ventricular systolic function in children undergoing bilateral lung transplantation for severe PAH

Georg Hansmann, Franziska Diekmann, Philippe Chouvarine, Fabio Ius, Julia Carlens, Nicolaus Schwerk, Gregor Warnecke, Jens Vogel-Claussen, Dagmar Hohmann, Tim Alten, Thomas JackEuropean Pediatric Pulmonary Vascular Disease Network. Hannover Medical School. University Hospital Heidelberg.Germany Journal of Heart and Lung TransplantationJ Heart Lung Transplant 2022; 41: 187-198DOI: 10.1016/j.healun.2021.10.014 AbstractBackground: We investigated whether RV function recovers in children with pulmonary […]

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Mesenchymal Stem Cell-derived Extracellular Vesicles Prevent Experimental Bronchopulmonary Dysplasia Complicated By Pulmonary Hypertension

Mayank Sharma, Michael A. Bellio, Merline Benny, Shathiyah Kulandavelu, Pingping Chen, Chawisa Janjindamai, Chenxu Han, Liming Chang, Shanique Sterling, Kevin Williams, Andreas Damianos, Sunil Batlahally, Kaitlyn Kelly, Daniela Aguilar-Caballero, Ronald Zambrano, Shaoyi Chen, Jian Huang, Shu Wu, Joshua M. Hare, Augusto Schmidt, Aisha Khan, Karen YoungUniversity of Miami Miller School of Medicine.United States Stem Cells Translational Medicine Stem Cells Transl Med 2022; 11: 828-840DOI: 10.1093/stcltm/szac041 AbstractMesenchymal stem cell (MSC) extracellular vesicles (EVs) have beneficial effects in preclinical bronchopulmonary

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Perinatal hypoxia aggravates occlusive pulmonary vasculopathy in SU5416/hypoxia-treated rats later in life

Hironori Oshita, Hirofumi Sawada, Yoshihide Mitani, Naoki Tsuboya, Jane C. Kabwe, Junko Maruyama, Ali yusuf, Hiromasa Ito, Ryuji Okamoto, Shoichiro Otsuki, Noriko Yodoya, Hiroyuki Ohashi, Kazunobu Oya, Yuhko Kobayashi, Issei Kobayashi, Kaoru Dohi, Yuhei Nishimura, Shinji Saitoh, Kazuo Maruyama, Masahiro HirayamaMie University Graduate School of Medicine. Nagoya City University Graduate School of Medical Sciences. Suzuka

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Effects of Inhaled Iloprost for the Management of Persistent Pulmonary Hypertension of the Newborn

Sourabh Verma, Rishi Lumba, Sadaf H. Kazmi, Michelle J. Vaz, Shrawani Soorneela Prakash, Sean M. Bailey, Pradeep V. Mally, Tara M. RandisNYU Grossman School of Medicine. University of South Florida. United States American Journal of PerinatologyAm J Perinatol 2022; 39: 1441-1448DOI: 10.1055/s-0040-1722653 AbstractObjective: The study aimed to evaluate the effects of inhaled iloprost on oxygenation indices in

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Milrinone Versus Sildenafil in Treatment of Neonatal Persistent Pulmonary Hypertension: A Randomized Control Trial

Safaa S. Iman, Rania A. El-Farrash, Amr S. Taha, Ghada A. SalehAin Shams University and Cairo Ministry of Health.Egypt Journal of Cardiovascular PharmacologyJ Cardiovasc Pharmacol 2022; 80: 746-752DOI: 10.1097/FJC.0000000000001332 AbstractPersistent pulmonary hypertension of the newborn (PPHN) is a condition caused by failure of pulmonary vascular adaptation at birth, resulting in severe hypoxia. Several therapeutic modalities are

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A case of acquired von Willebrand disease in severe pediatric pulmonary hypertension contributing to bleeding following reverse Potts shunt

Rachel T. Sullivan, Clara Lo, Elisabeth Martin, Rebecca J. Kameny, Rachel K. HopperStanford University School of Medicine and Lucile Packard Children’s Hospital.United States Pulmonary CirculationPulm Circ 2022; 12: DOI: 10.1002/pul2.12042 AbstractThe reverse Potts shunt is increasingly used as a palliative measure for end-stage pulmonary arterial hypertension (PAH) as a means to offload the right ventricle and

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A systematic review of clinical study evidence for pulmonary vasodilator therapy following surgery with cardiopulmonary bypass in children with CHD

Henry P. Foote, Christoph P. Hornik, Kevin D. Hill, Alexandre T. Rotta, Karan R. Kumar, Elizabeth J. ThompsonDuke University School of MedicineUnited States Cardiology in the YoungCardiol Young 2022; 20: DOI: 10.1017/S1047951122002293 AbstractObjectives: Complications from pulmonary hypertension are one of the leading contributors to morbidity and mortality post-cardiopulmonary bypass surgery in children with CHD. Pulmonary vasodilator therapies

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Factors associated with discontinuation of pulmonary vasodilator therapy in children with bronchopulmonary dysplasia-associated pulmonary hypertension

Catherine M. Avitabile, Xuemei Zhang, Steve B. Ampah, Yan Wang, Devon Ash, Kathleen Nilan, Laura Mercer-Rosa, Julie L. Fierro, David B. Frank, Kathleen A. GibbsUniversity of Pennsylvania and Children’s Hospital of Philadelphia.United States Journal of PerinatologyJ Perinatol 2022; 42: 1246-1254DOI: 10.1038/s41372-022-01421-6 AbstractObjective: To evaluate factors associated with discontinuation of pulmonary vasodilator therapy in bronchopulmonary dysplasia-related pulmonary hypertension

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Late onset of pulmonary hypertension in very low birth weight infants

Joseph Ginski, Dmitry Tumin, Devon Kuehn, Jason Higginson, Scott MacGilvrayEast Carolina UniversityUnited States Journal of Maternal Fetal and Neonatal MedicineJ Matern Fetal Neonatal Med 2022; 35: 3516-3518DOI: 10.1080/14767058.2020.1826924 AbstractIntroduction: Pulmonary hypertension (PH) is a recognized complication of bronchopulmonary dysplasia (BPD). Recent guidelines recommend evaluating all infants with BPD for PH via echocardiogram, but the specific timing of this screening

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Long-Term Outcomes in Adult Patients With Pulmonary Hypertension After Percutaneous Closure of Atrial Septal Defects

Selai Akseer, Lusine Abrahamyan, Douglas S. Lee, Ella Huszti, Lukas M. Meier, Mark Osten, Lee Benson, Eric HorlickUniversity of Toronto. University of Zurich. The Hospital for Sick Children.Canada and Switzerland Circulation Cardiovascular InterventionsCirc Cardiovasc Interv 2022; 15: DOI: 10.1161/CIRCINTERVENTIONS.121.011110 AbstractBackground: Pulmonary hypertension (PH), recently redefined as mean pulmonary arterial pressure >20 mm Hg (PH20), may be observed in patients with atrial septal defects (ASD). We aimed to determine the effect of preprocedural

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