Filed (PHiled). Greater than 1-2 years since publication

Clinical efficacy and safety of selexipag in children and young adults with idiopathic and heritable pulmonary arterial hypertension

Shinichi Takatsuki, Tomotaka Nakayama, Yurika Shimizu, Reiko Kawai, Hiroyuki MatsuuraToho University Omori Medical Center. Kochi Medical School Hospital.Japan Cardiology in the YoungCardiol Young 2023; 33: 196-200DOI: 10.1017/S1047951122000415 AbstractObjective: This study aimed to investigate the safety, tolerability, and efficacy of selexipag in children and young adults with idiopathic and heritable pulmonary arterial hypertension.Methods: This retrospective cohort study included clinical […]

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Misclassification of Pulmonary Hypertension in Partial Anomalous Pulmonary Venous Return

Clifford W. Chin, David P. BichellVanderbilt University and Monroe Carell Junior Children’s HospitalUnited States Annals of Thoracic SurgeryAnn Thorac Surg 2022; 114: e447-e449DOI: 10.1016/j.athoracsur.2022.02.021 AbstractPartial anomalous pulmonary venous return is a rare congenital heart defect that can escape detection until adulthood and can be misdiagnosed as pulmonary hypertension and managed with vasodilators before the anomaly is

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Prevalence of pulmonary hypertension on echocardiogram in children with severe obstructive sleep apnea

Melissa A. Maloney, Sally L. Davidson, Ramon A. Durazo-Arvizu, Jacqueline M. Breunig, Daniel U. Okpara, Emily S. GillettChildren’s Hospital Los Angeles and University of Southern California Keck School of Medicine.United States Journal of Clinical Sleep MedicineJ Clin Sleep Med 2022; 18: 1629-1637DOI: 10.5664/jcsm.9944 AbstractStudy objectives: Pulmonary hypertension (PH) is a rare yet serious complication of obstructive sleep

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Safety and Feasibility of Riociguat Therapy for the Treatment of Chronic Pulmonary Arterial Hypertension in Infancy

Regan E. Geisinger, Amy H. Stanford, Brady Thomas, Steven H. Abman, Patrick J. McNammaraUniversity of Iowa. University of Colorado.United States Journal of PediatricsJ Pediatr 2022; DOI: 10.1016/j.jpeds.2022.11.026 AbstractThe effects of riociguat, an oral-soluble guanylate-cyclase stimulator, were studied in 10 infants with chronic pulmonary arterial hypertension. Respiratory status (n = 8/10), right heart dilation (n = 7/10),

Safety and Feasibility of Riociguat Therapy for the Treatment of Chronic Pulmonary Arterial Hypertension in Infancy Read More »

Proteomics discovery of pulmonary hypertension biomarkers: Insulin-like growth factor binding proteins are associated with disease severity

Melanie K. Nies, Jun Yang, Megan Griffiths, Rachel Damico, Jie Zhu, Dhananjay Vaydia, Zongming Fu, Stephanie Brandal, Eric D. Austin, Dunbar D. Ivy, Paul M. Hassoun, Jennifer E. Van Eyk, Allen D. EverettJohns Hopkins University. Columbia University New York. Vanderbilt University. Children’s Hospital Colorado. Cedars-Sinai Medical Center.United States Pulmonary CirculationPulm Circ 2022; 12:DOI: 10.1002/pul2.12039 AbstractPulmonary arterial

Proteomics discovery of pulmonary hypertension biomarkers: Insulin-like growth factor binding proteins are associated with disease severity Read More »

Riociguat in children with pulmonary arterial hypertension: The PATENT-CHILD study

Humberto García Aguilar, Matthias Gorenflo, D. Dunbar Ivy, Shahin Moledina, Biagio Castaldi, Hidekazu Ishida, Paweł Cześniewicz, Jacek Kusa, Oliver Miera, Joseph Pattathu, Ken‐Pen Weng, Laszlo Ablonczy, Christian Apitz, Marta Katona, Kenichi Kurosaki, Tomas Pulido, Hiroyuki Yamagishi, Kazushi Yasuda, Galia Cisternas, Melanie Goth, Susanne Lippert, Anna Radomskyj, Soundos Saleh, Stefan Willmann, Gabriela Wirsching, Damien Bonnet, Maurice

Riociguat in children with pulmonary arterial hypertension: The PATENT-CHILD study Read More »

High-Altitude Pulmonary Edema in Colorado Children: A Cross-Sectional Survey and Retrospective Review

Timothy D. Kelly, Maxene Meier, Jason P. Weinman, Dunbar Ivy, John T. Brinton, Deborah R. LiptzinIndiana University. University of Colorado and Children’s Hospital Colorado. Colorado School of Public Health.United States High Altitude Medicine and BiologyHigh Alt Med Biol 2022; 23: 119-124DOI: 10.1089/ham.2021.0121 AbstractIntroduction: Few studies of high-altitude pulmonary edema (HAPE) are specific to the pediatric population. The

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Normalization of Four Different Types of Pulmonary Hypertension After Atrial Septal Defect Closure

Jana Rubáˇcková Popelová, Jakub Tomek, Markéta Tomková, Renata ŽivnáNa Homolce Hospital. Motol University Hospital. University of California, Davis.Czechia and United States Frontiers in Cardiovascular MedicineFront Cardiovasc Med 2022; 9: DOI: 10.3389/fcvm.2022.876755 AbstractPulmonary hypertension (PH) is an established risk factor in patients with atrial septal defect (ASD), and its persistence after ASD closure is associated with increased

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Echocardiographic Assessment of Pulmonary Hypertension in Neonates with Congenital Diaphragmatic Hernia Using Pulmonary Artery Flow Characteristics

Florian Kipfmueller, Lukas Schroeder, Ulrich Gembruch, Suemeyra Akkas, Flaminia Pugnaloni, Bartolomeo Bo, Lotte Lemloh, Annegret Geipel, Christoph Berg, Andreas Heydweiller, Andreas MuellerUniversity of Bonn. Ospidale Bambinu Gesu. University Hospital Cologne.Germany and Italy Journal of Clinical MedicineJ Clin Med 2022; 11: DOI: 10.3390/jcm11113038 AbstractBackground: Assessment of pulmonary hypertension (PH) is essential in neonates with congenital diaphragmatic hernia

Echocardiographic Assessment of Pulmonary Hypertension in Neonates with Congenital Diaphragmatic Hernia Using Pulmonary Artery Flow Characteristics Read More »

Clinical Significance of Early Pulmonary Hypertension in Preterm Infants

Sanne Arjaans, Marian W. F. Fries, Mirthe H. Schoots, Carine F. M. Schilte, Marc T. R. Roofthooft, Elianne J. L. E. Vrijlandt, Arie F. Bos, Elisabeth M. W. Kooi, Rolf M. F. BergerUniversity of Groningen, Beatrix Children’s Hospital and University Medical Center Groningen.Netherlands Journal of PediatricsJ Pediatr 2022; 251: 74-81DOI: 10.1016/j.jpeds.2022.07.039 AbstractObjective: To characterize different phenotypes of

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