Environmental Factors Associated with Pulmonary Vascular Disease

The High-Altitude Baby: Neonatal Development and Survival in Hypoxic Environments Neonatal Life in Hypobaric Hypoxia

Amed Soliz, Jorge SolizFlorida International University and Memorial Regional Hospital. Institute Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ) and Université Laval. Altitude Baby Association. United States and Canada Respiratory Physiology and NeurobiologyRespir Physiol Neurobiol 2026;DOI: 10.1016/j.resp.2026.104609 AbstractHigh altitude exposes the human fetus and newborn to chronic hypobaric hypoxia, markedly reducing oxygen availability during critical […]

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Child Opportunity Index Influences Pediatric Pulmonary Hypertension Outcomes: Analyses From the Pediatric Health Information System

Jai K. Khurana, Stuart Lipsitz, Diana L. Geisser, Katie M. Moynihan, Mary P. MullenBoston Children’s Hospital and Harvard Medical School.United States Journal of the American College of Cardiology AdvancesJACC Adv 2026; 5: DOI: 10.1016/j.jacadv.2026.102773 AbstractBackground: Social determinants of health (SDoH) in pediatric pulmonary hypertension (PH) outcomes are inadequately characterized.Objectives: The authors examined associations between SDoH and pediatric PH

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Pulmonary arterial hypertension in infancy: A case series

N. V. Shashikala, K. M. Arun, R. C. Ashwini, Muganagowda PatilBapuji Child Health Institute and Research Centre. India Tropical DoctorTrop Doct 2026;DOI: 10.1177/00494755261451113 AbstractThiamine deficiency is a reversible cause of severe pulmonary arterial hypertension (PAH) in early infancy, particularly among exclusively breastfed infants of mothers consuming polished rice-based diets. This retrospective case series (July 2023-July 2025)

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Lactobacillus Is Associated With Disease in Pulmonary Arterial Hypertension: A Prospective Cohort Study

Arun Jose, Senu Apewokin, Nicholas J. Ollberding, Qing Duan, Jennifer Trannguyen, Sasha Z. Prisco, Thenappan Thenappan, Anna R. Hemnes, Jean M. ElwinUniversity of Cincinnati and Cincinnati Children’s Hospital Medical Center. University of Minnesota. Vanderbilt University.United States Comprehensive PhysiologyComp Physiol 2026; 16: DOI: 10.1002/cph4.70161 AbstractBackground: Gut dysbiosis and gut-derived metabolites have been linked to pulmonary arterial hypertension. However,

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Severe Pertussis During Early Infancy from a High-Altitude Region: Two Clinical Cases and Literature Review

Hongju Chen, Sezhen Baima, Xiaoming Xu, Tao Wang, Jing ShiWest China Second University Hospital, Xizang Hospital, Sichuan, Xizang Autonomous Region Women’s and Children’s Hospital and Sichuan University.China Journal of Clinical MedicineJ Clin Med 2026; 15: DOI: 10.3390/jcm15062211 AbstractObjective: To investigate how the high-altitude environment modifies severe pertussis in young infants and analyze its pathophysiological mechanisms and

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The First 1000 Days: Maternal Nutrient Intake-A Window of Opportunity for Pulmonary Hypertension-A Narrative Review

Alina-Costina Luca, Solange Tamara Rosu, Cosmin Diaconescu, Dana Elena Mîndru, Cristina Gavrilovici, Adriana Vizireanu, Viorel Tarcă, Eduard Vasile Rosu, Elena TarcăGrigore T. Popa University of Medicine and Pharmacy. Apollonia University. Romania NutrientsNutrients 2026; 18: DOI: 10.3390/nu18030424 AbstractThe first 1000 days of life, starting from conception to a child’s second birthday, constitute a pivotal period for fetal

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Microbiome-Metabolome Axis in BALF Reveals Novel Diagnostic Biomarkers for Congenital Heart Disease-Associated Pulmonary Arterial Hypertension

Xiaoyu Zhang, Liming Cheng, Yuan Zhou, Jiahui Xie, Wenting Gui, Jiaxiang Chen, Zidan Zhang, Kai Liu, Runwei MaFuwai Yunnan Hospital, Chinese Academy of Medical Sciences, Affiliated Cardiovascular Hospital of Kunming Medical University. Kunming Children’s Hospital.China Journal of Cardiovascular Development and DiseaseJ Cardiovasc Dev Dis 2026; 13: DOI: 10.3390/jcdd13010032 AbstractBackground: Early identification of irreversible pulmonary vascular remodeling in

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Cardiovascular Manifestations and Interventions in Children Living in a Histoplasmosis Endemic Region

Cassandra Campbell, Sandra Arnold, Mario Briceno-Medina, Michael Perez, Shyam SathanandamUniversity of Pittsburgh Medical Center. Le Bonheur Children’s Hospital and University of Tennessee Health Science Center. Dell Children’s Medical Center. Nicklaus Children’s Hospital. United States Pediatric CardiologyPediatr Cardiol 2025; DOI: 10.1007/s00246-025-04123-w AbstractHistoplasmosis in children remains understudied, drawing most clinical understanding from adult populations. Located in a histoplasmosis-hyperendemic

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Cytochrome P450 1A1 influences obesity-induced pulmonary hypertension

Joshua P. Dignam, Smriti Sharma, Gregor Aitchison, Ayman Gebril, Ioannis Stasinopoulos, Sofia Laforest, Chelbi Coyle, Ruth Andrew, Natalie Z. M. Homer, Sébastien Bonnet, Sandra Breuils-Bonnet, Martin Wabitsch, Margaret R. MacLeanUniversity of Strathclyde. Queen Mary University of London. Medical University of Vienna. University of Edinburgh. Laval University. Ulm University Medical Center.United Kingdom, Austria, Canada and Germany

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Comparative assessment of nutritional status in unoperated children with Congenital Heart Defects: Insights from a tertiary pediatric cardiac center in India

Radha Joshi, Manasi Bhoite, Poonam Mandhare, Shaoni Nath, Sudhir Kapoor1, Rishikesh Wadke, Ragini PandeySri Sathya Sai Sanjeevani Research Foundation and Centre for Child Heart Care and Training in Paediatric Cardiac Skills. India Public Library of Science Global Public HealthPLOS Glob Publi Health 2025; 5: DOI: 10.1371/journal.pgph.0005260 AbstractCongenital Heart Defects (CHD) are structural cardiac malformations ranging from

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