Environmental Factors Associated with Pulmonary Vascular Disease

Severe Pertussis During Early Infancy from a High-Altitude Region: Two Clinical Cases and Literature Review

Hongju Chen, Sezhen Baima, Xiaoming Xu, Tao Wang, Jing ShiWest China Second University Hospital, Xizang Hospital, Sichuan, Xizang Autonomous Region Women’s and Children’s Hospital and Sichuan University.China Journal of Clinical MedicineJ Clin Med 2026; 15: DOI: 10.3390/jcm15062211 AbstractObjective: To investigate how the high-altitude environment modifies severe pertussis in young infants and analyze its pathophysiological mechanisms and […]

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The First 1000 Days: Maternal Nutrient Intake-A Window of Opportunity for Pulmonary Hypertension-A Narrative Review

Alina-Costina Luca, Solange Tamara Rosu, Cosmin Diaconescu, Dana Elena Mîndru, Cristina Gavrilovici, Adriana Vizireanu, Viorel Tarcă, Eduard Vasile Rosu, Elena TarcăGrigore T. Popa University of Medicine and Pharmacy. Apollonia University. Romania NutrientsNutrients 2026; 18: DOI: 10.3390/nu18030424 AbstractThe first 1000 days of life, starting from conception to a child’s second birthday, constitute a pivotal period for fetal

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Microbiome-Metabolome Axis in BALF Reveals Novel Diagnostic Biomarkers for Congenital Heart Disease-Associated Pulmonary Arterial Hypertension

Xiaoyu Zhang, Liming Cheng, Yuan Zhou, Jiahui Xie, Wenting Gui, Jiaxiang Chen, Zidan Zhang, Kai Liu, Runwei MaFuwai Yunnan Hospital, Chinese Academy of Medical Sciences, Affiliated Cardiovascular Hospital of Kunming Medical University. Kunming Children’s Hospital.China Journal of Cardiovascular Development and DiseaseJ Cardiovasc Dev Dis 2026; 13: DOI: 10.3390/jcdd13010032 AbstractBackground: Early identification of irreversible pulmonary vascular remodeling in

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Cardiovascular Manifestations and Interventions in Children Living in a Histoplasmosis Endemic Region

Cassandra Campbell, Sandra Arnold, Mario Briceno-Medina, Michael Perez, Shyam SathanandamUniversity of Pittsburgh Medical Center. Le Bonheur Children’s Hospital and University of Tennessee Health Science Center. Dell Children’s Medical Center. Nicklaus Children’s Hospital. United States Pediatric CardiologyPediatr Cardiol 2025; DOI: 10.1007/s00246-025-04123-w AbstractHistoplasmosis in children remains understudied, drawing most clinical understanding from adult populations. Located in a histoplasmosis-hyperendemic

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Cytochrome P450 1A1 influences obesity-induced pulmonary hypertension

Joshua P. Dignam, Smriti Sharma, Gregor Aitchison, Ayman Gebril, Ioannis Stasinopoulos, Sofia Laforest, Chelbi Coyle, Ruth Andrew, Natalie Z. M. Homer, Sébastien Bonnet, Sandra Breuils-Bonnet, Martin Wabitsch, Margaret R. MacLeanUniversity of Strathclyde. Queen Mary University of London. Medical University of Vienna. University of Edinburgh. Laval University. Ulm University Medical Center.United Kingdom, Austria, Canada and Germany

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Comparative assessment of nutritional status in unoperated children with Congenital Heart Defects: Insights from a tertiary pediatric cardiac center in India

Radha Joshi, Manasi Bhoite, Poonam Mandhare, Shaoni Nath, Sudhir Kapoor1, Rishikesh Wadke, Ragini PandeySri Sathya Sai Sanjeevani Research Foundation and Centre for Child Heart Care and Training in Paediatric Cardiac Skills. India Public Library of Science Global Public HealthPLOS Glob Publi Health 2025; 5: DOI: 10.1371/journal.pgph.0005260 AbstractCongenital Heart Defects (CHD) are structural cardiac malformations ranging from

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Scurvy, a not obsolete disorder: Clinical report in eight young children and literature review

Alessandra Di Nora, Maria Carla Finocchiaro, Francesco Pizzo, Trobia Gian Luca, Maria Elena Cucuzza, Antonella Di Stefano, Serena Spampinato, Silvia Marino, Martino Ruggieri, Piero PavoneUniversity of Catania. Cannizzaro Emergency Hospital. ARNAS Garibaldi Hospital.Italy Open MedicineOpen Med 2025; DOI: 10.1515/med-2024-1086 AbstractBackground: Vitamin C is a key to many important functions. It stimulates the immune system by protecting humans

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Inpatient outcomes among children with Down syndrome: a Kids’ Inpatient Database study

Po-Yang Tsou, Yu-Hsun Wang, Ignacio E. TapiaBoston Children’s Hospital and Harvard Medical School. Tufts Medical Center. University of Miami Health System.United States BioMedical Central PediatricsBMC Pediatr 2025; 25: DOI: 10.1186/s12887-025-05899-9 AbstractBackground: Children with Down Syndrome (DS) are more likely to have multi-system comorbidities leading to more frequent hospitalizations than the general population. We aim to evaluate whether

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Neighborhood Child Opportunity Index and Outcomes in Pediatric Pulmonary Hypertension

Jai Krishan Khurana, Stuart Lipsitz, Diana L. Geisser, Katie M. Moynihan, Mary P. MullenBoston Children’s Hospital, Brigham and Women’s Hospital and Harvard Medical School.United States Pediatric CardiologyPediatr Cardiol 2025; DOI: 10.1007/s00246-025-03981-8 AbstractThe role of social determinants of health (SDoH) in pediatric pulmonary hypertension (PH) outcomes are inadequately characterized. We hypothesized outcomes differ according to SDoH with

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Reassessment of the Current Iron Deficiency Definition in Pulmonary Hypertension

Aurelia E. Reiser, Markus Thiersch, Max Gassmann, Martina U. Muckenthaler, Thomas Geiser, Mona Lichtblau, Silvia UlrichUniversity of Zürich. University of Heidelberg. University of Berne.Switzerland and Germany Pulmonary CirculationPulm Circ 2025; 15: DOI: 10.1002/pul2.70142 AbstractIron deficiency (ID) is prevalent in pulmonary hypertension(PH), but there is no consensus on ID definition and its possible correlation to prognostic markers.

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