Diagnostic Testing for Pulmonary Vascular Disease. Risk Stratification

Predicting Outcomes in Pediatric Intraluminal Pulmonary Vein Stenosis Using a Comprehensive Standardized Catheterization Assessment: A Prospective Study

Ryan Callahan, Kimberlee Gauvreau, Mirjam Keochakian, Jesse J. Esch, Diego Porras, Lisa Bergersen, Rebecca Beroukhim, Michael Farias, David M. Harrild, Christina M. Ireland, Neha Kwatra, Kathy J. JenkinsChildren’s Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine. Boston Children’s Hospital and Harvard Medical School. United States Circulation Cardiovascular InterventionsCirc Cardiovasc Interv 2025; DOI: 10.1161/CIRCINTERVENTIONS.124.015002 […]

Predicting Outcomes in Pediatric Intraluminal Pulmonary Vein Stenosis Using a Comprehensive Standardized Catheterization Assessment: A Prospective Study Read More »

Echocardiographic Prediction of Hemodynamics During Acute Vasoreactivity Testing in Pediatric Pulmonary Arterial Hypertension

Charles T. Simpkin, Benjamin S. Frank, Yuanqing Liu, Zhaozing Pan, D. Dunbar Ivy, Dale A. BurkettChildren’s Hospital Colorado and University of Colorado-Anschutz Medical Campus.United States EchocardiographyEchocardiography 2025; DOI: 10.1111/echo.70232 AbstractPurpose: In pediatric pulmonary arterial hypertension (PAH), echocardiography is frequently used to assess response to acute vasodilator therapy. We sought to evaluate whether echocardiography is sensitive enough to

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Congenital diaphragmatic hernia with congenital heart disease including ventricular septal defect: Risk factors

Yuichi Hirano, Keita Terui, Wataru Kudo, Ayako Takenouchi, Shugo Komatsu, Saroru Oita, Hiroko Yoshizawa, Takashi Fumita, Yusaku Yoshino, Tomoro HishikiChiba University Graduate School of Medicine.Japan Pediatric InternationalPediatr Int 2025; DOI: 10.1111/ped.70126 AbstractBackground: Congenital diaphragmatic hernia (CDH) with congenital heart disease (CHD) has a poor prognosis. This study aimed to establish the prognostic factors of CDH associated with

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Performance of oral Bosentan-loaded SNEDDS and S-SNEDDS tablets: Biodistribution in mice, echocardiography and histology studies in pulmonary arterial hypertension rat model

Duygu Yilmaz Usta, Seval Olgac, Murside Ayse Demirel, Serdar Kula, Cigdem Elmas, Perihan Sezginer, Akif Kavgaci, Zeynep Safak TeksinGazi University. Alanya Alaadin Keykubat University. Turkey European Journal of Pharmaceutics and BiopharmaceuticsEur J Pharma Biopharma 2025; DOI: 10.1016/j.ejpb.2025.114725 AbstractBosentan monohydrate (BOS) is the most preferred molecule for treating the rare pulmonary arterial hypertension (PAH) disease. BOS shows

Performance of oral Bosentan-loaded SNEDDS and S-SNEDDS tablets: Biodistribution in mice, echocardiography and histology studies in pulmonary arterial hypertension rat model Read More »

Risk stratification in Eisenmenger syndrome

Estibaliz Valdeolmillos, Athenaïs Boucly, Marc Humbert, Olivier Sitbon, Laurent Savale, David Montani, Jérôme Le Pavec, Elie Fadel, Magalie Ladouceur, Emmanuelle Fournier, Gregoire Albenque, Bastien Provost, Clément Batteux, Alain Fraisse, Michael A. Gatzoulis, Aleksander Kempny, Sebastien HascoëtHôpital Marie Lannelongue, les hôpitaux Paris Saint-Joseph et Marie Lannelongue and Université Paris-Saclay. Hôpitaux Universitaires de Genève. Royal Brompton Hospital.

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Characteristics and sex differences in bronchopulmonary dysplasia-related pulmonary hypertension

Dansha Zhou, Ting Wang, Yuqin Chen, Yulin Zheng, Yingzhen Zhou, Mingxiang Zhang, Aofeng Liu, Biao Hu, Shuang Fu, Ruixian Wu, Wei Chen, Xiaoli Jiang, Zehui Ye, Yuan Shi, Zhou Fu, Jian WangFirst Affiliated Hospital of Guangzhou Medical University and Guangzhou Medical University. Children’s Hospital of Chongqing Medical University. China BioMedical Central Pulmonary MedicineBMC Pulm Med

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Differences in Pulmonary Artery Stiffness Measured by CMR in Preterm-Born Young Adults With and Without Bronchopulmonary Dysplasia

Wouter J. van Genuchten, Jarno J. Steenhorst, Gabrielle M. J. W. van Tussenbroek, Nikki van der Velde, Lieke S. Kamphuis, Irwin K. M. Reiss, Daphne Merkus, Willem A. Helbing, Alexander HirschErasmus MC. University Hospital Munich.Netherlands and Germany Circulation Cardiovascular ImagingCirc Cardiovasc Imaging 2025; DOI: 10.1161/CIRCIMAGING.124.017791 AbstractBackground: Very preterm-born infants are at risk for developing bronchopulmonary dysplasia (BPD), a chronic lung disease. Nowadays, the majority of these infants reach adulthood.

Differences in Pulmonary Artery Stiffness Measured by CMR in Preterm-Born Young Adults With and Without Bronchopulmonary Dysplasia Read More »

A machine learning approach to predict mortality and neonatal persistent pulmonary hypertension in newborns with congenital diaphragmatic hernia. A retrospective observational cohort study

Luana Conte, Ilaria Amodeo, Giorgio De Nunzio, Genny Rafaeli, Irene Borzani, Nicola Persico, Alice Griggio, Giuseppe Como, Mariarosa Colnaghi, Monica Fumagalli, Donato Cascio, Giacomo CavallaroUniversità Degli Studi Di Palermo. Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico. Laboratory of Interdisciplinary Research Applied to Medicine (DReAM). “E. De Giorgi”, University of Salento. Università Degli Studi Di Milano.

A machine learning approach to predict mortality and neonatal persistent pulmonary hypertension in newborns with congenital diaphragmatic hernia. A retrospective observational cohort study Read More »

Web server-based deep learning-driven predictive models for respiratory toxicity of environmental chemicals: Mechanistic insights and interpretability

Na Li, Zhaoyang Chen, Wenhui Zhang, Yan Li, Xin Huang, Xiao LiFirst Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital. China Journal of Hazardous MaterialsJ Hazard Mater 2025; 489: DOI: 10.1016/j.jhazmat.2025.137575 AbstractRespiratory toxicity of chemicals is a common clinical and environmental health concern. Currently, most in silico prediction models for chemical respiratory

Web server-based deep learning-driven predictive models for respiratory toxicity of environmental chemicals: Mechanistic insights and interpretability Read More »

Pertussis infection in critically ill infants: meta-analysis and validation of a mortality score

Vladimir L. Cousin, Caroline Caula, Jason Vignot, Raphael Joye, Matthieu Blanc, Clémence Marais, Pierre TissièresAP-HP Paris Saclay University, Bicêtre Hospital. Evelina London Children’s Hospital. Geneva University Hospital. Hospital for Sick Children and University of Toronto. France, United Kingdom, Switzerland and Canada Critical CareCrit Care 2025; 29: DOI: 10.1186/s13054-025-05300-2 AbstractBackground: Despite widespread vaccination programs, pertussis continues circulating within

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